Results 41 to 50 of about 17,734 (244)

Keloids [PDF]

JAMA Dermatology, 2021
Jared, Jagdeo, Eva, Kerby, Donald Alexander, Glass   +2 more
openaire   +2 more sources

Comparison of rat hypertrophic scar models: Caudal tension model with superior pathological consistency

Animal Models and Experimental Medicine, EarlyView.
This study compared hypertrophic scar (HS) formation in SD rats at ear, back, and tail sites with or without mechanical tension. The ear model healed spontaneously by day 30. Dorsal full‐thickness excision (1 × 8 cm) produced moderate HS. In contrast, the tail tension model showed the greatest scar thickness, fibroblast density, collagen deposition ...
Lingyi Zhan, Hong Xiang, Yaohui Kong, Yunfeng Lei, Shuqi Xiao, Shiqi Chen, Jiaming Li, Ziwei Li, Rui Ni, Dan Peng, Yao Liu   +10 more
wiley   +1 more source

Keloid-like Pilomatricoma of the Auricle: A Case Report and Review of Literature

, 2022
Pilomatricoma is a rare benign skin adnexal tumor arising from hair matrix cells. It usually manifests as a firm-to-hard, well-circumscribed, nontender nodule often mistaken as a dermoid cyst. However, its clinical presentation has been reported to mimic
Etnawati, Kristiana, Dewi, Shinta Trilaksmi, Rinonce, Hanggoro Tri, Wirohadidjojo, Yohanes Widodo   +3 more
core   +1 more source

Ferrostatin-1 inhibits fibroblast fibrosis in keloid by inhibiting ferroptosis [PDF]

PeerJ
Background Keloid is a chronic proliferative fibrotic disease caused by abnormal fibroblasts proliferation and excessive extracellular matrix (ECM) production.
Liu Yang, Xiuli Li, Yanli Wang
doaj   +2 more sources

Single-cell RNA-seq reveals the communications between extracellular matrix-related components and Schwann cells contributing to the earlobe keloid formation

Frontiers in Medicine, 2022
Keloid is a major type of skin fibrotic disease, with one prominent feature of extensive accumulation of extracellular matrix (ECM) components, and another feature of pain/itching, which is closely related to the peripheral nervous system (PNS). However,
Taogen Gong, Taogen Gong, Yayu Wang, Shaowei Dong, Xiaoshi Ma, Danfeng Du, Chang Zou, Qijun Zheng, Zhong Wen   +8 more
doaj   +1 more source

Repeated intradermal lipopolysaccharide challenge responses in healthy volunteers: Implications for clinical pharmacology studies

British Journal of Clinical Pharmacology, EarlyView.
Aim Intradermal application of lipopolysaccharide (LPS), a Toll‐like receptor 4 agonist, induces a local inflammatory response and is used as a human challenge model to evaluate the pharmacodynamics of investigational medicinal products. While currently applied in a single, parallel‐group setting, alternative within‐subject designs involving repeated ...
Alexandra A. J. Sillé, Juliette A. van den Noort, Iva Lelios, Diana R. Pereira, Marzia A. Scelsi, Erica S. Klaassen, Philipp Schoenenberger, Naomi B. Klarenbeek, Pierre‐Eric Juif, Pascal Espie, Manon A. A. Jansen, Matthijs Moerland, Richard W. D. Welford   +12 more
wiley   +1 more source

A case with reconstructoin of the floor of the oral cavity and mandibular region with the D-P flap after resection of giant keloid and radiation scar of the mandibular [PDF]

, 1990
P(論文)The floor of the oral cavity and mandibular of a 27-year-old female was reconstructed with the D-P flap after resection of a giant keloid in the submandibular region and a radiation scar of the mandibular.
36280, 22639, 柴田, 敏之, 麻生, 智義, 36288, 36287, 36286, 北村, 完二, 36285, 36284, 36283, 36282, 36281, 深瀬, 秀郷, 富永, 恭弘, 36289, 田中, 真樹, 藤田, 浄秀, 富田, 喜内, 斉藤, 基明, 平, 博彦, 村瀬, 博文, 36279, 36278, 本橋, 雪子, 原田, 尚也   +25 more
core  

Reduced Hyaluronan in Keloid Tissue and Cultured Keloid Fibroblasts [PDF]

, 2000
Extracellular matrix hyaluronan is prominent during wound healing, appearing at elevated levels early in the repair process. It is prevalent throughout the course of fetal wound healing, which is scar-free, but decreases late in adult wound repair, that ...
Trupin, Joel S., Stern, Robert, Russell, James D., Meyer, Ludger J.M., Egbert, Barbara M., Shuster, Svetlana, Russell, Shirley B.   +6 more
core   +1 more source

IFNγ regulates ferroptosis in KFs by inhibiting the expression of SPOCD1 through DNMT3A

Cell Death Discovery
Keloid is benign skin tumor, and their curing is relatively difficult due to the unclear mechanism of formation. Inducing ferroptosis of keloid fibroblasts (KFs) may become a new method for treating keloid.
Xiuxia Wang, Yating Yang, Xianyu Zhou, Shun Yu, Xusong Luo, Lin Lu, Zhen Gao, Jun Yang   +7 more
doaj   +1 more source

3D Printing a Clinically Available Solution From Plaster‐Based Positives in Superficial Radiation Therapy

Journal of Medical Radiation Sciences, EarlyView.
This study compares two techniques for creating lead shielding masks to replace the current process for superficial/orthovoltage facial radiotherapy: Plaster Cast Positive Mould (PCPM), CT Scanned 3D Print (CT3DP), and Optical Scan 3D Print (OS3DP). CT3DP was found to be more accurate and preferred over OS3DP.
Rory Hartley, Linda Bell, Toby Lowe, Jeremy Booth, Sarah Bergamin, Dasantha Jayamanne, Ryan Brown   +6 more
wiley   +1 more source