Results 81 to 90 of about 40,839 (332)

Epigenetic modification mechanisms involved in keloid: current status and prospect

open access: yesClinical Epigenetics, 2020
Keloid, a common dermal fibroproliferative disorder, is benign skin tumors characterized by the aggressive fibroblasts proliferation and excessive accumulation of extracellular matrix.
Wenchang Lv   +8 more
semanticscholar   +1 more source

circNRIP1 facilitates keloid progression via FXR1-mediated upregulation of miR-503-3p and miR-503-5p

open access: yesInternational Journal of Molecular Medicine, 2021
Circular nuclear receptor interacting protein 1 (circNRIP1) is implicated in tumor initiation and progression; however, the underlying mechanism of keloid progression is unclear.
Baolin Wang   +3 more
semanticscholar   +1 more source

IFNγ regulates ferroptosis in KFs by inhibiting the expression of SPOCD1 through DNMT3A

open access: yesCell Death Discovery
Keloid is benign skin tumor, and their curing is relatively difficult due to the unclear mechanism of formation. Inducing ferroptosis of keloid fibroblasts (KFs) may become a new method for treating keloid.
Xiuxia Wang   +7 more
doaj   +1 more source

Smart Biomaterials and Dressings for the Treatment of Chronic Inflammatory Skin Diseases

open access: yesRare Metals, EarlyView.
ABSTRACT Chronic inflammatory skin diseases, encompassing immune‐inflammatory conditions and infection‐associated dermatoses, pose significant clinical challenges due to high prevalence, recurrence, and therapeutic resistance, affect over 30% of the global population.
Zehao Lan   +5 more
wiley   +1 more source

Heteroenxerto de quelóide na bolsa jugal do hamster (Mesocricetus auratus) [PDF]

open access: yes, 2005
PURPOSE: To study the integration of keloid heterograft in hamster (Mesocricetus auratus) cheek pouch. METHODS: The sample is formed by 18 male hamsters, heterogenic ones, aged between 10 and 14 weeks.
Ferreira, Lydia Masako   +3 more
core   +4 more sources

Activating transcription factor 3 (ATF3) regulates cell growth, apoptosis, invasion and collagen synthesis in keloid fibroblast through transforming growth factor beta (TGF-beta)/SMAD signaling pathway

open access: yesBioengineered, 2020
The successful treatment of keloids is a great challenge in the plastic surgery field. Activating transcription factor 3 (ATF3) is discovered as an adaptive responsive gene, which plays a critical role in fibroblast activation.
Xueming Wang   +3 more
semanticscholar   +1 more source

Keloid Scars: An Updated Review of Combination Therapies

open access: yesCureus, 2021
Keloid scars are a common yet poorly understood complication of wound healing that can cause a diminished quality of life. Currently, there is little agreement amongst the medical community regarding the best treatment modality for keloids.
Nicholas J Thornton   +3 more
semanticscholar   +1 more source

Robotic‐Assisted Transaxillary Parathyroidectomy: A Safe and Cosmetically Alternative for Primary Hyperparathyroidism

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Purpose This study aimed to describe the initial experience with robot‐assisted transaxillary parathyroidectomy (RATP) and to investigate its safety and efficacy as a surgical approach for the treatment of primary hyperparathyroidism (PHPT).
Xi‐Jun Lin   +7 more
wiley   +1 more source

3D keloid spheroid model: Development and application for personalized drug response prediction

open access: yesCommunications Biology
Research on keloid is limited by the lack of proper in vitro and animal model reflecting in vivo status. Based on heterogeneity of keloid and important role of endothelial cells in its pathogenesis, a novel 3D in vitro keloid spheroid prepared with ...
YoungHwan Choi   +9 more
doaj   +1 more source

In vivo terahertz imaging to evaluate scar treatment strategies : silicone gel sheeting [PDF]

open access: yes, 2019
Silicone gel sheeting (SGS) is widely used for scar treatment; however, studies showing its interaction with skin and efficacy of scar treatment are still lacking.
Ahuja, Anil T.   +5 more
core   +1 more source

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