Results 81 to 90 of about 29,071 (276)

USP37-stabilized SALL4 promotes the keloid formation by PI3K/AKT pathway

open access: yesScientific Reports
Spalt-like transcription factor 4 (SALL4) plays a vital role in the progression of many human diseases. However, the role and mechanism of SALL4 regulates in keloid formation remain unclear.
Shuo Fang   +6 more
doaj   +1 more source

Increased epidermal thickness and abnormal epidermal differentiation in keloid scars [PDF]

open access: yes, 2016
Background: The pathogenesis underlying keloid formation is still poorly understood. Research has focused mostly on dermal abnormalities, while the epidermis has not yet been studied.
Everts, V   +8 more
core   +3 more sources

PLK4 is a potential therapeutic target in nonmelanoma skin cancers: Evidence from molecular and in vivo studies

open access: yesPhotochemistry and Photobiology, EarlyView.
Exposure to solar ultraviolet radiation is the main etiologic driver of nonmelanoma skin cancers (NMSCs), including basal cell (BCC) and cutaneous squamous cell carcinomas (cSCC), which are the most prevalent types of cancers in the US. In this study, we demonstrate that the serine/threonine kinase Polo‐like kinase 4 (PLK4) is overexpressed in NMSCs ...
Mary A. Ndiaye   +5 more
wiley   +1 more source

Keloid Patient Plasma-Derived Exosomal hsa_circ_0020792 Promotes Normal Skin Fibroblasts Proliferation, Migration, and Fibrogenesis via Modulating miR-193a-5p and Activating TGF-β1/Smad2/3 Signaling

open access: yesDrug Design, Development and Therapy, 2022
Huan Hu,* Guangyu Mao,* Jianghong Zheng, Feng Guo Department of Plastic Surgery, Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200233, People’s Republic of China*These authors ...
Hu H, Mao G, Zheng J, Guo F
doaj  

Treatment of keloid [PDF]

open access: yesThe Laryngoscope, 1977
AbstractA case is presented in which a large infected keloid of the back of the neck was widely excised and the edges of the tumor were injected with triamcinolone acetate. The area was covered with partial thickness skin graft. The steroid injections were continued postoperatively. At fourteen months follow‐up, there is no evidence of recurrence.
openaire   +3 more sources

Hyaluronic acid: A novel approach in regenerative/reconstructive periodontal therapy?

open access: yesPeriodontology 2000, EarlyView.
Abstract Background Although hyaluronic acid (HA) has long been used for many medical applications, only in recent years has it gained greater popularity in the field of periodontics because of its biological effects during wound healing. Even today, most clinicians are not aware that more than one type of HA exists and that the extent of its ...
Andrea Pilloni   +7 more
wiley   +1 more source

Dysregulation of DPP4-CXCL12 Balance by TGF-β1/SMAD Pathway Promotes CXCR4+ Inflammatory Cell Infiltration in Keloid Scars

open access: yesJournal of Inflammation Research, 2021
ZongAn Chen,1,* Zhen Gao,1,* LingLing Xia,1 XiaoQing Wang,2,* LiMing Lu,3,* XiaoLi Wu1,* 1Department of Plastic and Reconstructive Surgery, Shanghai Ninth People’s Hospital, Shanghai JiaoTong University School of Medicine, Shanghai ...
Chen Z, Gao Z, Xia L, Wang X, Lu L, Wu X
doaj  

The Poet\u27s Corner [PDF]

open access: yes, 1986
A collection of poems sent in by ...

core   +1 more source

BCG and adverse events in the context of leprosy [PDF]

open access: yes, 2018
Background: Notwithstanding its beneficial immunoprophylactic outcomes regarding leprosy and childhood TB, BCG vaccination may cause adverse events, particularly of the skin.
Annemieke Geluk   +7 more
core   +3 more sources

Scars and keloids [PDF]

open access: yesBMJ, 2004
Several treatments are used, but the evidence base is lacking The reparative response of a fetus to injury is regeneration of tissue without scar. However, in children and adults the inevitable response to injury is scar formation, which in skin causes disfigurement and may result in restriction of motion.
openaire   +2 more sources

Home - About - Disclaimer - Privacy