Results 61 to 70 of about 5,007,575 (281)

Keratin-Templated Synthesis of Metallic Oxide Nanoparticles as MRI Contrast Agents and Drug Carriers

, 2018
Keratin is a family of cysteine-rich structural fibrous proteins abundantly present in skin and skin appendages. Inspired by the template synthesis strategy, in this work, keratin was utilized for the first time as a platform template to synthesize ...
Chen Peng (429537), Yan Li (23143), Kai Song (107003), Yu Cao (274482), Guang Yang (154978)   +4 more
core   +1 more source

Hydrogel‐Based Airway‐on‐Tube With Perfusable Endothelial Lumen and Outward Epithelialization

Advanced Materials, EarlyView.
A hydrogel‐based airway‐on‐tube platform featuring a perfusable endothelial lumen and outward epithelialization is presented. The system supports primary human bronchial epithelial and lung microvascular endothelial coculture under air‐liquid interface conditions.
Ali Doryab, Jack F. Murphy, Michael Bartolf‐Kopp, Jenny C‐C Hsin, Alice Chernaik, Frank McCaughan, Yan Yan Shery Huang, Tomasz Jungst, Jürgen Groll   +8 more
wiley   +1 more source

Immune Cells Profiles in the Different Sites of COVID-19-Affected Lung Lobes in a Single Patient

Frontiers in Medicine, 2022
Whereas the COVID-19 disease pathophysiology is under investigation, it is important to identify the pathways of viral transmission and inflammation from the pre-illness to the disease-onset stages.
Sadahiro Iwabuchi, Kyohei Miyamoto, Mayuko Hatai, Yurina Mikasa, Masahiro Katsuda, Shin-ichi Murata, Toshikazu Kondo, Hiroki Yamaue, Shinichi Hashimoto   +8 more
doaj   +1 more source

A Ca2+-Mediated Switch of Epiplakin from a Diffuse to Keratin-Bound State Affects Keratin Dynamics

, 2022
Keratins exert important structural but also cytoprotective functions. They have to be adaptable to support cellular homeostasis. Epiplakin (EPPK1) has been shown to decorate keratin filaments in epithelial cells and to play a protective role under ...
Rudolf E. Leube, Fuchs, Peter, Reinhard Windoffer, Peter Fuchs, Ratajczyk, Sonia, Corinne Drexler, Leube, Rudolf E., Sonia Ratajczyk, Drexler, Corinne, Windoffer, Reinhard   +9 more
core   +1 more source

Keratin–Melanin Complexation Enables Robust, Delamination‐Resistant Feather‐Inspired Structural Color Coatings for Flexible and Curved Substrates

Advanced Materials Interfaces, EarlyView.
Providing mechanically robust structural color coating technology inspired by cooperative interactions in nature. The spatial arrangement of melanin particles within the keratin matrix generates angle‐independent structural colors. Diverse functional groups in keratin and melanin contribute to interparticle and substrate adhesion, resulting in the ...
Taisei Harada, Yui Maejima, Ryota Iwamori, Hideyuki Mitomo, Hirotoshi Tamayama, Shin‐ichi Takeda, Daisuke Unabara, Tasuku Hamaguchi, Koji Yonekura, Gen Morimoto, Hiroshi Fudouzi, Keiki Kishikawa, Michinari Kohri   +12 more
wiley   +1 more source

Identification of a population of epidermal squamous cell carcinoma cells with enhanced potential for tumor formation. [PDF]

PLoS ONE, 2013
Epidermal squamous cell carcinoma is among the most common cancers in humans. These tumors are comprised of phenotypically diverse populations of cells that display varying potential for proliferation and differentiation. An important goal is identifying
Gautam Adhikary, Dan Grun, Candace Kerr, Sivaprakasam Balasubramanian, Ellen A Rorke, Mohan Vemuri, Shayne Boucher, Jackie R Bickenbach, Thomas Hornyak, Wen Xu, Matthew L Fisher, Richard L Eckert   +11 more
doaj   +1 more source

One-pot process: Microwave-assisted keratin extraction and direct electrospinning to obtain keratin-based bioplastic [PDF]

, 2021
Poultry feathers are among the most abundant and polluting keratin-rich waste bio-masses. In this work, we developed a one-pot microwave-assisted process for eco-friendly keratin extraction from poultry feathers followed by a direct electrospinning (ES ...
Pelosi C., Bramanti E., Bernazzani L., Pulidori E., De Acutis A., Duce C., Montemurro F., Vozzi G., Tine M. R., Micalizzi S., De Maria C.   +10 more
core   +1 more source

TOLLIP Inhibits Psoriasis Progression via Suppressing PKM2‐Mediated Glycolysis in Keratinocytes

Advanced Science, EarlyView.
In this study, we identify TOLLIP as a critical regulator of psoriasis pathogenesis through its modulation of glycolytic metabolism. Our findings establish the TOLLIP‐PKM2‐glycolysis axis as a key mechanism linking metabolic reprogramming to psoriasis pathogenesis, and propose TOLLIP as a promising therapeutic target.
Xiuhuan Jiang, Guoying Miao, Na Shen, Qingxia Han, Xiaoru Han, Zichang Qiao, Kexin Feng, Zhuo Tan, Yaguang Wang, Xiuhua Liu, Chen Wu, Zhenzhen Yan   +11 more
wiley   +1 more source

Immunohistochemical demonstration of keratins in the epidermal layers of the Malayan pangolin (Manis javanica), with remarks on the evolution of the integumental scale armour

European Journal of Histochemistry, 2013
Using immunohistochemistry, the study demonstrates the distribution of keratins (pan-keratin with CK1-8, 10, 14-16, 19; keratins CK1, 5, 6, 9, 10; hair keratins AE13, AE14) in the epidermis of the Malayan pangolin (Manis javanica).
W. Meyer, M. Liumsiricharoen, A. Suprasert, L.G. Fleischer, M. Hewicker-Trautwein   +4 more
doaj   +1 more source

Keratin 19 im Verdauungssystem

, 2018
Keratine stellen Intermediärfilamente der Epithelzellen dar. K19 gehört mit K7, K8, K18 und K20 zu den Keratinen der einschichtigen Epithelien. In der Leber wird es in den Gallengangepithelien und hepatischen Stammzellen, nicht aber in adulten Hepatozyten exprimiert.
openaire   +2 more sources