Results 91 to 100 of about 55,822 (247)

Carcinomas assemble a filamentous CXCL12-keratin-19 coating that suppresses T cell-mediated immune attack. [PDF]

Proc Natl Acad Sci U S A, 2022
Wang Z, Moresco P, Yan R, Li J, Gao Y, Biasci D, Yao M, Pearson J, Hechtman JF, Janowitz T, Zaidi RM, Weiss MJ, Fearon DT.   +12 more
europepmc   +1 more source

Anticancer potential of berberine: Molecular pathways and current clinical trial perspectives

JSFA reports, EarlyView.
Abstract Cancer is constantly rising mortality rates due to its late prognosis, poor management, and expensive treatment. Multi‐sectoral approaches for cancer management include hygienic practices, synthetic drug exploitation, radiation therapy, and diet modifications.
Muhammad Maaz, Muhammad Tauseef Sultan, Muhammad Israr, Waqas Ahmad Khan, Fahad Tanveer, Muzzamal Hussain, Muhammad Imran, Ahmed Mujtaba, Anjuman Gul Memon, Muhammad Atif, Entessar Al Jbawi   +10 more
wiley   +1 more source

Bromelain as the enzyme of the future: A global bibliometric mapping of its applications and emerging trends

Journal of the Science of Food and Agriculture, EarlyView.
Abstract INTRODUCTION Bromelain, a complex mixture of proteolytic enzymes primarily extracted from plants of the Bromeliaceae family, has gained prominence because of its broad industrial applicability, particularly in the food, pharmaceutical and cosmetic sectors.
Genésio José da Silva Neto, Tonny Cley Campos Leite, Mônica Tejo Cavalcanti, Geany Targino Sousa Pedrosa, Rerisson do Nascimento Alves, Amanda Reges de Sena, Mônica Correia Gonçalves   +6 more
wiley   +1 more source

High‐ and Ultra‐High‐Frequency Ultrasound Identifies a Subclinical Link Between Suppurative Comedonal Nevus and Hidradenitis Suppurativa

Journal of Ultrasound in Medicine, EarlyView.
Suppurative nevus comedonicus (SNC) is a variant of nevus comedonicus in which the characteristic features coexist with recurrent inflammatory lesions that clinically resemble those of hidradenitis suppurativa (HS). We present the ultrasound characteristics of this entity and emphasize the value of high‐resolution dermatologic ultrasound both as a ...
Marta Ivars, Katia Henostroza, Fabià Torres‐Betato, Eva Vilarrasa, Ximena Wortsman   +4 more
wiley   +1 more source

Chromosomal Localization of Candidate Genes for Fiber Growth and Color in Alpaca (Vicugna pacos)

Frontiers in Genetics, 2019
The alpaca (Vicugna pacos) is an economically important and cultural signature species in Peru. Thus, molecular genomic information about the genes underlying the traits of interest, such as fiber properties and color, is critical for improved breeding ...
Mayra N. Mendoza, Terje Raudsepp, Fahad Alshanbari, Gustavo Gutiérrez, F. Abel Ponce de León   +4 more
doaj   +1 more source

Validation of the Investigator's Global Assessment Scale for Epidermolysis Bullosa Simplex

JEADV Clinical Practice, EarlyView.
ABSTRACT Background There is a lack validated outcome measures to assess wound severity in epidermolysis bullosa simplex (EBS). Objectives To assess the reliability and validity of the Investigator's Global Assessment (IGA) scale and a newly developed palms/soles subscale through in‐clinic scoring and review of patient‐submitted photographs.
Pirunthan Pathmarajah, Shufeng Li, Maya B. Mathur, Joyce M. C. Teng, M. Peter Marinkovich, Austin N. Johnson, Shehla Admani, Edward Eid, Joanna Tu, Dominique C. Mitchell, Lila Perrone, Ricardo Villanueva Gaona, Jean Y. Tang, Albert S. Chiou   +13 more
wiley   +1 more source

Prognostic significance of inflammation-based prognostic scoring in patients with upper urinary tract urothelial carcinoma

International Brazilian Journal of Urology
Objectives: To investigate whether Glasgow Prognostic Score has prognostic significance in patients with upper urinary urothelial carcinoma. Patients and methods: We retrospectively reviewed the clinical records of 74 patients with upper urinary ...
Taisuke Suyama, Shigeki Kanbe, Masanobu Maegawa, Hirofumi Shimizu, Koichi Nakajima   +4 more
doaj   +1 more source

Loss of Keratin 19 predisposes to the development of cholestatic liver disease

, 2014
Keratins (K) are cytoprotective proteins and keratin mutations predispose to development of multiple human diseases. K19 represents the most widely used biliary and liver progenitor cell (LPC) marker. Since K19 variants were found in patients with primary biliary cirrhosis (PBC), we investigated the role of K19 in cholangiocytes and LPCs. K19 wild-type
openaire   +2 more sources

Nail Toxicities Associated With Anticancer Therapies in Children

JEADV Clinical Practice, EarlyView.
ABSTRACT Nail toxicities are a frequent yet often underrecognized component of dermatologic adverse events in children receiving anticancer therapies. Both conventional cytotoxic chemotherapy and newer targeted agents can affect the nail matrix, nail bed and periungual tissues, producing a broad spectrum of clinical manifestations that range from ...
Luca Rapparini, Michela Starace
wiley   +1 more source

The Early Regenerative Events in the Human Tympanic Membrane After In Vivo Traumatization

The Laryngoscope, EarlyView.
At 20 h after in vivo traumatization a regenerative response in the human tympanic membrane is activated. The results show an upregulated proliferation activity in the UPT in early healing and confirm the previously described regenerative regions of the annulus and malleus.
Elnaz Sepehri, Cecilia Engmér Berglin, Yan Liu, Per Olof Eriksson, Magnus von Unge, Julia Arebro   +5 more
wiley   +1 more source