Results 41 to 50 of about 5,007,575 (281)

Histomorphological observation of surgical debridement combined with negative pressure therapy in treatment of diabetic foot

Chinese Journal of Traumatology, 2017
Purpose: To further study the mechanism of epithelization on the fascia side of the flap after surgical incision and the treatment of the negative pressure therapy.
Jiao-Yun Dong, Fei Song, Chun Qing, Shu-Liang Lu   +3 more
doaj   +1 more source

Clinical and Prognostic Significances of Cytokeratin 19 and KIT Expression in Surgically Resectable Pancreatic Neuroendocrine Tumors [PDF]

Journal of Pathology and Translational Medicine, 2015
Background: Pancreatic neuroendocrine tumors (PanNETs) are malignant endocrine neoplasms that present diverse clinical behaviors. Therefore, identification of biomarkers of PanNETs is important for stratification of the prognosis of PanNET patients ...
Eun-Mi Son, Joo Young Kim, Soyeon An, Ki-Byung Song, Song Cheol Kim, Eunsil Yu, Seung-Mo Hong   +6 more
doaj   +1 more source

Similarities in DSG1 and KRT3 Downregulation through Retinoic Acid Treatment and PAX6 Knockdown Related Expression Profiles: Does PAX6 Affect RA Signaling in Limbal Epithelial Cells?

Biomolecules, 2021
Congenital PAX6-aniridia is a rare panocular disease resulting from limbal stem cell deficiency. In PAX6-aniridia, the downregulation of the retinol-metabolizing enzymes ADH7 (All-trans-retinol dehydrogenase 7) and ALDH1A1/A3 (Retinal dehydrogenase 1 ...
Lorenz Latta, Igor Knebel, Constanze Bleil, Tanja Stachon, Priya Katiyar, Claire Zussy, Fabian Norbert Fries, Barbara Käsmann-Kellner, Berthold Seitz, Nóra Szentmáry   +9 more
doaj   +1 more source

Immunohistochemical Demonstration of Keratin 19 Expression in Isolated Human Hair Follicles

Journal of Investigative Dermatology, 1994
We examined keratins 19 and 8 in extracted human hair follicles using monoclonal antibodies Ks19.1 and CAM5.2, respectively. Ks19.1 reactivity was found in the bulge and infundibulum. Ks19.1(+) cells were dense in the bulge of vellus and intermediate hair follicles. The intact bulge of terminal hair could not be extracted, but the presence of Ks19.1(+)
Narisawa, Yutaka, Kohda, Hiromu, Hashimoto, K.e.n.   +2 more
openaire   +2 more sources

Keratin 19 protein expression is an independent predictor of survival in human hepatocellular carcinoma [PDF]

European Journal of Gastroenterology & Hepatology, 2015
We aimed to assess the clinicopathological relevance and prognostic significance of expression of the hepatic progenitor cell markers keratin 19 (K19), epithelial cell adhesion molecule (EpCAM) and CD117 (c-KIT) in a White series of hepatocellular carcinoma (HCC).We evaluated the immunohistochemical expression of K19, EpCAM and CD117 in 89 surgical ...
Fatourou E, Koskinas J, Karandrea D, Palaiologou M, Syminelaki T, Karanikolas M, Felekouras E, Antoniou E, Manesis EK, Delladetsima J, Tiniakos D   +10 more
openaire   +4 more sources

Keratin intermediate filaments in the colon: guardians of epithelial homeostasis [PDF]

, 2020
Keratin intermediate filament proteins are major cytoskeletal components of the mammalian simple layered columnar epithelium in the gastrointestinal tract.
Heikkil�, Taina, Tayyab, Mina, Baghestani, Sarah, Toivola, Diana M., Nystr�m, Joel H., Alam, Catharina M., Polari, Lauri   +6 more
core   +1 more source

The Type I Keratin 19 Possesses Distinct and Context-dependent Assembly Properties [PDF]

Journal of Biological Chemistry, 1998
Keratins (K), the cytoplasmic intermediate filament (IF) proteins of epithelial cells, are encoded by a multigene family and expressed in a tissue- and differentiation-specific manner. In human skin, keratinocytes of the basal layer of epidermis and the outer root sheath of hair follicles express K5 and K14 as their main keratins. A small subpopulation
J, Fradette, L, Germain, P, Seshaiah, P A, Coulombe   +3 more
openaire   +2 more sources

Keratin 19: Predicted amino acid sequence and broad tissue distribution suggest it evolved from keratinocyte keratins [PDF]

, 1989
The type I keratin 19 is unusual in its tissue distribution in that under normal circumstances it does not seem to be restricted, as the other keratins are, to expression in either stratified or simple epithelia.
Leigh, Irene M., Birgitte Lane, E., Purkis, Patricia E., Stasiak, Pauline C.   +3 more
core   +1 more source

Chicken keratin‐19: Cloning of cDNA and analysis of expression in the chicken embryonic gut [PDF]

Development, Growth & Differentiation, 1997
From many recent studies, it has been argued that keratins (cytokeratins) play important roles in the morphogenesis and differentiation of organ development. To learn the role of keratin in digestive tract development, a cDNA of the chicken homolog of keratin‐19 (GK‐19) was cloned and its expression pattern was analyzed in the digestive tract of ...
K, Sato, S, Yasugi
openaire   +2 more sources

Serum keratin 19 (CYFRA21‐1) is a prognostic biomarker in severe alcoholic hepatitis

Liver International, 2022
AbstractBackground and AimsUp to 30% of patients with severe alcoholic hepatitis (sAH) die within 3 months of presentation. The degree of ductular reaction, characterized by accumulation of biliary and liver progenitor cells, confers a poor prognosis.
Stephen Rahul Atkinson, Mahmoud Aly, Katharina Remih, Luke David Tyson, Nurdan Guldiken, Robert Goldin, Alberto Quaglia, Mark Thursz, Pavel Strnad   +8 more
openaire   +3 more sources