Results 51 to 60 of about 3,543,538 (259)

Keratin-Graphene Nanocomposite: Transformation of Waste Wool in Electronic Devices

open access: yes, 2019
Electronic devices, designed to be long lasting, are commonly made with rigid, nondegradable materials. These, together with the presence of rare and toxic elements, create significant issues for their waste management.
Davide Spirito (3330324)   +6 more
core   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

Keratin-positive stromal cells are confined within the elastic lamina of the peritoneal membrane (VVG and pan-keratin).

open access: yes, 2017
Adenocarcinoma of the colon invades the peritoneal membrane with uneven fraying of the elastic fibers of the elastic lamina. At low magnification, the keratin-positive stromal cells appear to extend past the elastic lamina and into the subserosa (A and B,
Jey-Hsin Chen (3830464)   +1 more
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Genomic organization and amplification of the human keratin 15 and keratin 19 genes

open access: yes, 2000
Keratin intermediate filaments are the major components of the cytoskeleton in epithelial cells. Mutations in keratin genes have been documented in many disorders of the skin, nails, hair, and mucous membranes.
McGrath, J A, Whittock, N V, Eady, R A J
core   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

open access: yesMolecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski   +12 more
wiley   +1 more source

Immunohistochemical demonstration of keratins in the epidermal layers of the Malayan pangolin (Manis javanica), with remarks on the evolution of the integumental scale armour

open access: yesEuropean Journal of Histochemistry, 2013
Using immunohistochemistry, the study demonstrates the distribution of keratins (pan-keratin with CK1-8, 10, 14-16, 19; keratins CK1, 5, 6, 9, 10; hair keratins AE13, AE14) in the epidermis of the Malayan pangolin (Manis javanica).
W. Meyer   +4 more
doaj   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

open access: yesFEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Keratin 19: Predicted amino acid sequence and broad tissue distribution suggest it evolved from keratinocyte keratins

open access: yes, 1989
The type I keratin 19 is unusual in its tissue distribution in that under normal circumstances it does not seem to be restricted, as the other keratins are, to expression in either stratified or simple epithelia.
Leigh, Irene M.   +3 more
core   +1 more source

Keratin intermediate filaments in the colon: guardians of epithelial homeostasis

open access: yes, 2020
Keratin intermediate filament proteins are major cytoskeletal components of the mammalian simple layered columnar epithelium in the gastrointestinal tract.
Heikkil�, Taina   +6 more
core   +2 more sources

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