Results 31 to 40 of about 3,543,405 (295)

Keratin 19 protein expression is an independent predictor of survival in human hepatocellular carcinoma [PDF]

European Journal of Gastroenterology & Hepatology, 2015
We aimed to assess the clinicopathological relevance and prognostic significance of expression of the hepatic progenitor cell markers keratin 19 (K19), epithelial cell adhesion molecule (EpCAM) and CD117 (c-KIT) in a White series of hepatocellular carcinoma (HCC).We evaluated the immunohistochemical expression of K19, EpCAM and CD117 in 89 surgical ...
Fatourou E, Koskinas J, Karandrea D, Palaiologou M, Syminelaki T, Karanikolas M, Felekouras E, Antoniou E, Manesis EK, Delladetsima J, Tiniakos D   +10 more
openaire   +4 more sources

One-pot process: Microwave-assisted keratin extraction and direct electrospinning to obtain keratin-based bioplastic [PDF]

, 2021
Poultry feathers are among the most abundant and polluting keratin-rich waste bio-masses. In this work, we developed a one-pot microwave-assisted process for eco-friendly keratin extraction from poultry feathers followed by a direct electrospinning (ES ...
Pelosi C., Bramanti E., Bernazzani L., Pulidori E., De Acutis A., Duce C., Montemurro F., Vozzi G., Tine M. R., Micalizzi S., De Maria C.   +10 more
core   +1 more source

Histomorphological observation of surgical debridement combined with negative pressure therapy in treatment of diabetic foot

Chinese Journal of Traumatology, 2017
Purpose: To further study the mechanism of epithelization on the fascia side of the flap after surgical incision and the treatment of the negative pressure therapy.
Jiao-Yun Dong, Fei Song, Chun Qing, Shu-Liang Lu   +3 more
doaj   +1 more source

The Type I Keratin 19 Possesses Distinct and Context-dependent Assembly Properties [PDF]

Journal of Biological Chemistry, 1998
Keratins (K), the cytoplasmic intermediate filament (IF) proteins of epithelial cells, are encoded by a multigene family and expressed in a tissue- and differentiation-specific manner. In human skin, keratinocytes of the basal layer of epidermis and the outer root sheath of hair follicles express K5 and K14 as their main keratins. A small subpopulation
J, Fradette, L, Germain, P, Seshaiah, P A, Coulombe   +3 more
openaire   +2 more sources

Clinical and Prognostic Significances of Cytokeratin 19 and KIT Expression in Surgically Resectable Pancreatic Neuroendocrine Tumors [PDF]

Journal of Pathology and Translational Medicine, 2015
Background: Pancreatic neuroendocrine tumors (PanNETs) are malignant endocrine neoplasms that present diverse clinical behaviors. Therefore, identification of biomarkers of PanNETs is important for stratification of the prognosis of PanNET patients ...
Eun-Mi Son, Joo Young Kim, Soyeon An, Ki-Byung Song, Song Cheol Kim, Eunsil Yu, Seung-Mo Hong   +6 more
doaj   +1 more source

Influences of Desmin and Keratin 19 on Passive Biomechanical Properties of Mouse Skeletal Muscle [PDF]

Journal of Biomedicine and Biotechnology, 2012
In skeletal muscle fibers, forces must be transmitted between the plasma membrane and the intracellular contractile lattice, and within this lattice between adjacent myofibrils. Based on their prevalence, biomechanical properties and localization, desmin and keratin intermediate filaments (IFs) are likely to participate in structural connectivity and ...
Shah, Sameer B., Love, James M., O'Neill, Andrea, Lovering, Richard M., Bloch, Robert J.   +4 more
openaire   +2 more sources

TNF receptor–related factor 3 inactivation promotes the development of intrahepatic cholangiocarcinoma through NF‐κB‐inducing kinase–mediated hepatocyte transdifferentiation

Hepatology, EarlyView., 2022
Abstract Background and Aims Intrahepatic cholangiocarcinoma (ICC) is a deadly but poorly understood disease, and its treatment options are very limited. The aim of this study was to identify the molecular drivers of ICC and search for therapeutic targets.
Yuto Shiode, Takahiro Kodama, Satoshi Shigeno, Kazuhiro Murai, Satoshi Tanaka, Justin Y. Newberg, Jumpei Kondo, Shogo Kobayashi, Ryoko Yamada, Hayato Hikita, Ryotaro Sakamori, Hiroshi Suemizu, Tomohide Tatsumi, Hidetoshi Eguchi, Nancy A. Jenkins, Neal G. Copeland, Tetsuo Takehara   +16 more
wiley   +1 more source

Chicken keratin‐19: Cloning of cDNA and analysis of expression in the chicken embryonic gut [PDF]

Development, Growth & Differentiation, 1997
From many recent studies, it has been argued that keratins (cytokeratins) play important roles in the morphogenesis and differentiation of organ development. To learn the role of keratin in digestive tract development, a cDNA of the chicken homolog of keratin‐19 (GK‐19) was cloned and its expression pattern was analyzed in the digestive tract of ...
K, Sato, S, Yasugi
openaire   +2 more sources

AIF1+CSF1R+ MSCs, induced by TNF‐α, act to generate an inflammatory microenvironment and promote hepatocarcinogenesis

Hepatology, EarlyView., 2022
Mesenchymal stem cells subset, educated by TNF‐α, are involved to generate inflammatory microenvironment and promote hepatocarcinogenesis Abstract Background and Aims Increasing evidence suggests that mesenchymal stem cells (MSCs) home to injured local tissues and the tumor microenvironment in the liver.
Chen Zong, Yan Meng, Fei Ye, Xue Yang, Rong Li, Jinghua Jiang, Qiudong Zhao, Lu Gao, Zhipeng Han, Lixin Wei   +9 more
wiley   +1 more source

Heterogeneity of estrogen receptor expression in circulating tumor cells from metastatic breast cancer patients. [PDF]

PLoS ONE, 2013
BACKGROUND: Endocrine treatment is the most preferable systemic treatment in metastatic breast cancer patients that have had an estrogen receptor (ER) positive primary tumor or metastatic lesions, however, approximately 20% of these patients do not ...
Anna Babayan, Juliane Hannemann, Julia Spötter, Volkmar Müller, Klaus Pantel, Simon A Joosse   +5 more
doaj   +1 more source