Results 11 to 20 of about 3,543,405 (295)

Morphology, Motility, and Cytoskeletal Architecture of Breast Cancer Cells Depend on Keratin 19 and Substrate. [PDF]

Cytometry A, 2020
AbstractCancer cells gain motility through events that accompany modulation of cell shape and include altered expression of keratins. However, the role of keratins in change of cancer cell architecture is not well understood. Therefore, we ablated the expression of keratin 19 (K19) in breast cancer cells of the MDA‐MB‐231 cell line and found that cells
Lam VK, Sharma P, Nguyen T, Nehmetallah G, Raub CB, Chung BM.   +5 more
europepmc   +4 more sources

Voiding symptoms aggravate with decreasing stromal/epithelial ratio and increasing glandular-epithelial content in patients undergoing laser enucleation for benign prostatic hyperplasia, independently from prostate size. [PDF]

PLoS ONE
IntroductionBenign prostatic hyperplasia (BPH) includes epithelial, stromal and mixed hyperplasia, but their specific contributions to voiding symptoms and prostate volume (PV) are unknown.
Patrick Keller, Sheng Hu, Wenbin Zhu, Yajie Xu, Laurenz Berger, Philip Nicola, Philipp Weinhold, Alexander Tamalunas, Christian G Stief, Martin Hennenberg   +9 more
doaj   +2 more sources

Heterogeneity of Epigenetic and Epithelial Mesenchymal Transition Marks in Hepatocellular Carcinoma with Keratin 19 Proficiency. [PDF]

Liver Cancer, 2019
<b><i>Objective:</i></b> Keratin 19 (K19) expression is a potential predictor of poor prognosis in patients with hepatocellular carcinoma (HCC). To clarify the feature of K19-proficient HCC, we traced epigenetic footprints in cultured cells and clinical materials.
Yokomichi N, Nishida N, Umeda Y, Taniguchi F, Yasui K, Toshima T, Mori Y, Nyuya A, Tanaka T, Yamada T, Yagi T, Fujiwara T, Yamaguchi Y, Goel A, Kudo M, Nagasaka T.   +15 more
europepmc   +4 more sources

Keratin 19 as a key molecule in progression of human hepatocellular carcinomas through invasion and angiogenesis. [PDF]

BMC Cancer, 2016
Keratin (K) 19-positive hepatocellular carcinoma (HCC) is well known to have a higher malignant potential than K19-negative HCC: However, the molecular mechanisms involved in K19-mediated progression of HCC remain unclear. We attempted to clarify whether K19 directly affects cell survival and invasiveness in association with cellular senescence or ...
Takano M, Shimada K, Fujii T, Morita K, Takeda M, Nakajima Y, Nonomura A, Konishi N, Obayashi C.   +8 more
europepmc   +3 more sources

Keratin as a Potential Prognostic Biomarker for Breast Cancer Progression: An Evidence-Synthesizing Narrative Review [PDF]

Breast Cancer: Targets and Therapy
Astrid Feinisa Khairani,1 Karina Fitria Alhaq,2 Regina Indrasari Herriyanto,2 Mh Busra Fauzi,3 Nayla Majeda Alfarafisa1 1Department of Biomedical Sciences, Faculty of Medicine, Universitas Padjadjaran, Bandung, West Java, Indonesia; 2Faculty of Medicine,
Khairani AF, Alhaq KF, Herriyanto RI, Fauzi MB, Alfarafisa NM   +4 more
doaj   +2 more sources

Improving the Adsorption Properties of Keratin-Based Goat Hair Toward Reactive Dyes in Dyeing Wastewater by Steam Explosion

Journal of Natural Fibers, 2023
Keratin-based goat hair could be used bioadsorbent due to its large availability, biodegradability and low cost. Unfortunately, most available keratin adsorbents are either low in adsorption capacity or high in preparation cost.
Shijin Wei, Xiuliang Hou, Linyun Liu, Yue Tian, Wei Li, Helan Xu   +5 more
doaj   +1 more source

Efficient isolation of keratin from protein-rich waste biomass: a practical approach to minimize environmental impact and valorize waste biomass

Sustainable Environment Research, 2022
Among various protein-containing biomass wastes, waste animal wool, poultry feather, and human hair are considered one of the most important renewable sources of keratin.
Tapan Kumar Maity, Nripat Singh, Pradipkumar Vaghela, Arup Ghosh, Sanju Singh, Pramod B. Shinde, Rosy Alphons Sequeira, Kamalesh Prasad   +7 more
doaj   +1 more source

Keratin 19: a key role player in the invasion of human hepatocellular carcinomas [PDF]

Gut, 2013
Objective Keratin (K)19, a biliary/hepatic progenitor cell (HPC) marker, is expressed in a subset of hepatocellular carcinomas (HCC) with poor prognosis. The underlying mechanisms driving this phenotype of K19-positive HCC remain elusive. Design
Govaere, Olivier, Komuta, M.Ina, Berkers, Joost, Spee, Bart, Janssen, Carl, de Luca, Francesca, Katoonizadeh, Aezam, Wouters, Jasper, van Kempen, Léon C., Durnez, Anne, Verslype, Chris, De Kock, Joery, Rogiers, Vera, van Grunsven, Leo A., Topal, Baki, Pirenne, Jacques, Vankelecom, Hugo, Nevens, Frederik, van den Oord, Joost, Pinzani, Massimo, Roskams, Tania   +20 more
openaire   +7 more sources

Keratin 19 Epithelial Patterns in Cirrhotic Stroma Parallel Hepatocarcinogenesis [PDF]

The American Journal of Pathology, 2011
Cirrhotic septa harbor vessels and inflammatory, fibrogenic, and ductular epithelial cells, collectively referred to as the ductular reaction (DR). Lack of the DR in the stromal compartment around hepatocellular carcinoma (HCC) has been documented; however, the relationship of epithelial keratin 19 (K19) structures to progression of intralesional ...
Jochen K M, Lennerz, William C, Chapman, Elizabeth M, Brunt   +2 more
openaire   +2 more sources

No difference in keratin thickness between inner and outer foreskins from elective male circumcisions in Rakai, Uganda. [PDF]

PLoS ONE, 2012
It has been hypothesized that increased HIV acquisition in uncircumcised men may relate to a more thinly keratinized inner foreskin. However, published data are contradictory and potentially confounded by medical indications for circumcision.
Minh H Dinh, Taha Hirbod, Godfrey Kigozi, Eneniziaogochukwu A Okocha, Gianguido C Cianci, Xiangrong Kong, Jessica L Prodger, Kristina Broliden, Rupert Kaul, David Serwadda, Maria J Wawer, Ronald H Gray, Thomas J Hope   +12 more
doaj   +1 more source