Results 141 to 150 of about 5,007,575 (281)

Global Multidisciplinary Variation in Idiopathic Subglottic Stenosis Surgical Management

open access: yesThe Laryngoscope, EarlyView.
This international cross‐sectional survey of 193 clinicians across 42 countries reveals substantial global and multidisciplinary variation in the surgical management of idiopathic subglottic stenosis (iSGS). While endoscopic dilation remains near‐universally utilized, practice patterns differ significantly regarding technical execution, adjuvant ...
Emilie A. C. Dronkers   +7 more
wiley   +1 more source

Spatial transcriptomics reveals club cell features and strong CLDN18 expression along the mucinous pathway to invasive mucinous adenocarcinoma

open access: yesThe Journal of Pathology, EarlyView.
Abstract Invasive mucinous adenocarcinoma (IMA) of the lung is a distinct subtype of lung adenocarcinoma with unique clinicopathologic features; however, its histogenesis remains incompletely understood. Although mucinous metaplasia has been suspected as a precursor lesion, direct molecular evidence supporting this progression is limited. In this study,
Joon Young Park   +5 more
wiley   +1 more source

Identification of Novel Interacting Proteins of FUZ and GPR161

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Protein–protein interactions are central to the dynamic regulation of signaling pathways and provide critical insight into the cellular mechanisms underlying human disease. Our previous study demonstrated biochemical and genetic interactions between FUZ and GPR161 in sonic hedgehog signaling during spinal neural tube development. In this study,
Gabriella Salazar   +3 more
wiley   +1 more source

Using MALDI‐FTICR Mass Spectrometry to Enhance ZooMS Identifications of Pleistocene Bone Fragments Showing Variable Collagen Preservation

open access: yesRapid Communications in Mass Spectrometry, EarlyView.
ABSTRACT Rationale Recent advances in high‐throughput molecular analyses of collagen peptides, especially ZooMS (Zooarchaeology by Mass Spectrometry), have permitted breakthroughs in the analysis of archaeological material that is highly fragmented, a factor that hinders morphological identification.
Pauline Raymond   +8 more
wiley   +1 more source

High keratinase and other types of hydrolase activity of the new strain of Bacillus paralicheniformis.

open access: yesPLoS ONE
Keratinases, a subclass of proteases, are used to degrade keratin thereby forming peptones and free amino acids. Bacillus paralicheniformis strain T7 was isolated from soil and exhibited high keratinase, protease, collagenase, amylase, xylanase, lipase ...
Saniya Aktayeva, Bekbolat Khassenov
doaj   +1 more source

Synergistic Effects of Cosolvents on the Dissolution of Wool Keratin Using Ionic Liquids

open access: yes, 2016
Keratin, regenerated from wool fibers, is widely used in the textile and medicine fields. In this work, a series of synthesized 1-butyl-3-methylimidazolium-based ionic liquids (IL) were used to dissolve wool keratin.
Zhang, Xiangping   +5 more
core   +1 more source

Foamed Concrete Sealing Materials for Coal Seam Gas Drainage Boreholes: A Review

open access: yesSafety Science and Technology, EarlyView.
This study investigates the sealing performance of foamed concrete in gas drainage boreholes. By comparing leakage pathways (a, c) with sealed systems (b, d), the research demonstrates how foamed concrete effectively fills mining‐induced fractures and resists deformation.
Jiaxing Zou   +6 more
wiley   +1 more source

Biomarkers to predict outcomes in diabetic foot ulcers

open access: yesVIEW, EarlyView.
Studies attempting to predict the healing outcome of diabetic foot ulcers (DFUs) have investigated various biological materials and recovered molecules that may aid in discriminating wounds that will heal and those that will not heal. This graphical abstract captures the commonly studied classes of biomarkers in the context of DFUs.
Julie Okiro   +6 more
wiley   +1 more source

Peptide‐directed nanovehicles enabling tumor‐selective ROS amplification and antitumor immunity

open access: yesVIEW, EarlyView.
Cancer cells are vulnerable to oxidative stress, yet exploit immune tolerance to escape destruction. In contrast, their metabolic profile is markedly altered to support rapid proliferation, accompanied by elevated production of reactive oxygen species (ROS).
Manuela Calin   +3 more
wiley   +1 more source

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