Results 41 to 50 of about 3,543,538 (259)

Biofunctional approaches of wool-based keratin for tissue engineering

, 2021
The use of bioactive materials has become a standard tool in the arsenal of tissue engineering and regenerative medicine applications. Bioactive materials have gained great attention due to their ability to mimic tissues physically, chemically and ...
Ranjit, Eliza, George, Roy, Hamlet, Stephen, Love, Robert, Sharma, Ajay   +4 more
core   +1 more source

MCF-7 Human Breast Cancer Cells Form Differentiated Microtissues in Scaffold-Free Hydrogels.

PLoS ONE, 2015
Three-dimensional (3D) cultures are increasing in use because of their ability to represent in vivo human physiology when compared to monolayer two-dimensional (2D) cultures.
Marguerite M Vantangoli, Samantha J Madnick, Susan M Huse, Paula Weston, Kim Boekelheide   +4 more
doaj   +1 more source

Cross-talk between microRNA-let7c and transforming growth factor-β2 during epithelial-to-mesenchymal transition of retinal pigment epithelial cells [PDF]

International Journal of Ophthalmology, 2020
AIM: To explore the roles of microRNA-let7c (miR-let7c) and transforming growth factor-β2 (TGF-β2) and cellular signaling during epithelial-to-mesenchymal transition (EMT) of retinal pigment epithelial cells. METHODS: Retinal pigment epithelial (ARPE-19)
Qu-Zhen Deji, Feng Yan, Wang-Dui Zhaba, Ya-Jun Liu, Jie Yin, Zhen-Ping Huang   +5 more
doaj   +1 more source

Laccase-assisted approach to graft multifunctional materials of interest: keratin-EC based novel composites and their characterisation [PDF]

, 2015
This study focuses on the evaluation of raw keratin as a potential material to develop composites with novel characteristics. Herein, we report a mild and eco-friendly fabrication of in-house extracted feather keratin-based novel enzyme assisted ...
Kyazze, G., Keshavarz, T., Iqbal, H.M.N., Tron, T.   +3 more
core   +1 more source

Lung Cancer-Associated Keratin 19 Fragments: Development and Biochemical Characterisation of the New Serum Assay Enzymun-Test Cyfra 21–1

The International Journal of Biological Markers, 1994
From a panel of 4 murine monoclonal antibodies directed against keratin 19 various antibody combinations were evaluated in solid-phase enzyme-linked sandwich immunoassays for detection of soluble keratin 19 fragments in patient sera.
H. Bodenmüller, B. Ofenloch-Hähnle, E.B. Lane, A. Dessauer, V. Böttger, F. Donié   +5 more
doaj   +1 more source

Detection of lymph node metastasis in lung cancer patients using a one-step nucleic acid amplification assay: a single-centre prospective study

Journal of Translational Medicine, 2019
Background The use of one-step nucleic acid amplification (OSNA) allows for lymph node (LN) metastasis to be detected rapidly and accurately. We conducted a prospective single-centre clinical trial to evaluate OSNA assay in detecting LN metastasis of ...
María Escalante Pérez, María Teresa Hermida Romero, Begoña Otero Alén, Mónica Álvarez Martínez, Ricardo Fernández Prado, Mercedes de la Torre Bravos, Ángel Concha López   +6 more
doaj   +1 more source

Immune Cells Profiles in the Different Sites of COVID-19-Affected Lung Lobes in a Single Patient

Frontiers in Medicine, 2022
Whereas the COVID-19 disease pathophysiology is under investigation, it is important to identify the pathways of viral transmission and inflammation from the pre-illness to the disease-onset stages.
Sadahiro Iwabuchi, Kyohei Miyamoto, Mayuko Hatai, Yurina Mikasa, Masahiro Katsuda, Shin-ichi Murata, Toshikazu Kondo, Hiroki Yamaue, Shinichi Hashimoto   +8 more
doaj   +1 more source

Functionalization Routes for Keratin from Poultry Industry Side-Streams—Towards Bio-Based Absorbent Polymers [PDF]

, 2023
Keratin is a largely available protein that can be obtained from the ca. 3 million tons of feathers that the European poultry industry produces as a side-stream.
Pérez-Puyana, Víctor Manuel, Hendeqvist, Mikael S., Capezza, Antonio Jose,, William R. Newson, Bengoechea, Carlos, Bengoechea, Carlos,, Johansson, Eva,, Hedenqvist, Mikael S.,, Antonio Guerrero, Newson, William R.,, Victor M. Perez-Puyana, Carlos Bengoechea, Eva Johansson, Newson, William, Antonio J. Capezza, Guerrero, Antonio,, Capezza, Antonio J., Perez-Puyana, Victor M., Guerrero, Antonio, Mikael S. Hendeqvist, Perez-Puyana, Victor M.,, Bengoechea Ruiz, Carlos, Newson, William R., Guerrero Conejo, Antonio Francisco, Johansson, Eva   +24 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Identification of a population of epidermal squamous cell carcinoma cells with enhanced potential for tumor formation. [PDF]

PLoS ONE, 2013
Epidermal squamous cell carcinoma is among the most common cancers in humans. These tumors are comprised of phenotypically diverse populations of cells that display varying potential for proliferation and differentiation. An important goal is identifying
Gautam Adhikary, Dan Grun, Candace Kerr, Sivaprakasam Balasubramanian, Ellen A Rorke, Mohan Vemuri, Shayne Boucher, Jackie R Bickenbach, Thomas Hornyak, Wen Xu, Matthew L Fisher, Richard L Eckert   +11 more
doaj   +1 more source