Results 1 to 10 of about 53,032 (257)

The Complexity of the Ovine and Caprine Keratin-Associated Protein Genes. [PDF]

Int J Mol Sci, 2021
Sheep (Ovis aries) and goats (Capra hircus) have, for more than a millennia, been a source of fibres for human use, be it for use in clothing and furnishings, for insulation, for decorative and ceremonial purposes, or for combinations thereof. While use of these natural fibres has in some respects been superseded by the use of synthetic and plant-based
Zhou H, Gong H, Wang J, Luo Y, Li S, Tao J, Hickford JGH.   +6 more
europepmc   +5 more sources

Wool Keratin-Associated Protein Genes in Sheep-A Review. [PDF]

Genes (Basel), 2016
The importance of sheep’s wool in making textiles has inspired extensive research into its structure and the underlying genetics since the 1960s. Wool keratin-associated proteins (KAPs) are a key structural component of the wool fibre. The characterisation of the genes encoding these proteins has progressed rapidly with advances in the nucleotide and ...
Gong H, Zhou H, Forrest RH, Li S, Wang J, Dyer JM, Luo Y, Hickford JG.   +7 more
europepmc   +5 more sources

Ovine KRTAP36-2: A New Keratin-Associated Protein Gene Related to Variation in Wool Yield. [PDF]

Genes (Basel), 2023
Keratin-associated proteins (KAPs) are structural components of wool fibres. High-glycine/tyrosine (HGT)-KAPs are a subset of the KAP family, and their abundance in fibres varies. In this study, we report the discovery of an ovine HGT-KAP gene to which we assigned the name KRTAP36-2. Polymerase chain reaction and single-strand conformation polymorphism
Zhou H, Li W, Bai L, Wang J, Luo Y, Li S, Hickford JGH.   +6 more
europepmc   +4 more sources

A highly polymorphic caprine keratin-associated protein gene identified and its effect on cashmere traits. [PDF]

J Anim Sci, 2021
Abstract Five keratin-associated protein 6 genes (KRTAP6) have been identified in sheep and variation in some KRTAP6 has been associated with wool fiber diameter-related traits, but none of these homologues have been identified in goats.
Li S, Xi Q, Zhao F, Wang J, He Z, Hu J, Liu X, Luo Y.   +7 more
europepmc   +3 more sources

An Updated Nomenclature for Keratin-Associated Proteins (KAPs) [PDF]

International Journal of Biological Sciences, 2012
Most protein in hair and wool is of two broad types: keratin intermediate filament-forming proteins (commonly known as keratins) and keratin-associated proteins (KAPs).
Hua Gong, Huitong Zhou, Grant W. McKenzie, Zhidong Yu, Stefan Clerens, Jolon M. Dyer, Jeffrey E. Plowman, Mathew W. Wright, Reena Arora, C. Simon Bawden, Yulin Chen, Jinquan Li, Jonathan G. H. Hickford
doaj   +5 more sources

Keratin-associated protein 5-5 controls cytoskeletal function and cancer cell vascular invasion. [PDF]

Oncogene, 2017
Cancer cell vascular invasion is a crucial step in the malignant progression toward metastasis. Here we used a genome-wide RNA interference screen with E0771 mammary cancer cells to uncover drivers of endothelial monolayer invasion. We identified keratin-associated protein 5-5 (Krtap5-5) as a candidate.
Berens EB, Sharif GM, Schmidt MO, Yan G, Shuptrine CW, Weiner LM, Glasgow E, Riegel AT, Wellstein A.   +8 more
europepmc   +4 more sources

Variation in the caprine keratin-associated protein 15-1 (KAP15-1) gene affects cashmere fibre diameter [PDF]

Archives Animal Breeding, 2019
Keratin-associated proteins (KAPs) are a structural component of cashmere fibre, and variation in some KAP genes (KRTAPs) has been associated with a number of caprine fibre traits.
M. Zhao, M. Zhao, H. Zhou, H. Zhou, H. Zhou, J. G. H. Hickford, J. G. H. Hickford, J. G. H. Hickford, H. Gong, H. Gong, J. Wang, J. Wang, J. Hu, J. Hu, X. Liu, X. Liu, S. Li, S. Li, Z. Hao, Z. Hao, Y. Luo, Y. Luo   +21 more
doaj   +2 more sources

Cornified Epithelial Teeth of Jawless Vertebrates Contain Proteins Similar to Keratin-Associated Proteins of Mammalian Skin Appendages

Journal of Developmental Biology
Keratins and keratin-associated proteins (KRTAPs) are the main components of mammalian nails and hair. Comparative genomics and gene expression studies have revealed that keratins are conserved in all vertebrates, whereas KRTAPs exist only in mammals ...
Attila Placido Sachslehner, David A. D. Parry, Leopold Eckhart   +2 more
doaj   +3 more sources

Molecular characterization and expression pattern of a novel Keratin-associated protein 11.1 gene in the Liaoning cashmere goat () [PDF]

Asian-Australasian Journal of Animal Sciences, 2017
Objective An experiment was conducted to determine the relationship between the KAP11.1 and the regulation wool fineness. Methods In previous work, we constructed a skin cDNA library and isolated a full-length cDNA clone termed KAP11.1. On this basis, we
Mei Jin, Qian Cao, Ruilong Wang, Jun Piao, Fengqin Zhao, Jing’ai Piao   +5 more
doaj   +2 more sources

The effect of androgen on wool follicles and keratin production in Hetian sheep [PDF]

Brazilian Journal of Biology, 2021
To investigate the optimal androgen concentration for culturing Hetian sheep wool follicle and to detect effects of androgen concentration on wool follicle cell proliferation and apoptosis using immunofluorescence labeling and real-time quantitative ...
H. Y. Wang, S. W. Li, T. H. Wu, Z. H. Wu, J. X. Guo   +4 more
doaj   +1 more source