Results 51 to 60 of about 88,954 (294)

Proteomic Analysis of Crimped and Straight Wool in Chinese Tan Sheep

Animals
Crimped wool in Tan sheep gradually transitions to straight wool after 35 days (the er-mao stage), which reduces its commercial value. To investigate the changes in wool proteins during this stage, we performed comparative proteomic analysis of the ...
An Shi, Sijia Ma, Zhuo Yang, Wei Ding, Jinyang Tian, Xin Chen, Jinzhong Tao   +6 more
doaj   +1 more source

Correction: Molecular evolution of the keratin associated protein gene family in mammals, role in the evolution of mammalian hair

BMC Evolutionary Biology, 2009
Correction to Wu DD, Irwin DM, Zhang YP: Molecular evolution of the keratin associated protein gene family in mammals, role in the evolution of mammalian hair. BMC Evol Biol 2008, 8:241.
Irwin David M, Wu Dong-Dong, Zhang Ya-Ping   +2 more
doaj   +1 more source

Evolutionary origin and diversification of epidermal barrier proteins in amniotes. [PDF]

, 2014
The evolution of amniotes has involved major molecular innovations in the epidermis. In particular, distinct structural proteins that undergo covalent cross-linking during cornification of keratinocytes facilitate the formation of mechanically resilient ...
Alibardi, Lorenzo, Eckhart, Leopold, Eigenheer, Richard A, Hermann, Marcela, Mlitz, Veronika, Rice, Robert H, Strasser, Bettina, Tschachler, Erwin   +7 more
core   +1 more source

Dose-dependent onset of regenerative program in neutron irradiated mouse skin. [PDF]

PLoS ONE, 2011
BACKGROUND: Tissue response to irradiation is not easily recapitulated by cell culture studies. The objective of this investigation was to characterize, the transcriptional response and the onset of regenerative processes in mouse skin irradiated with ...
Emiliano Fratini, Valerio Licursi, Mara Artibani, Katarzyna Kobos, Paolo Colautti, Rodolfo Negri, Roberto Amendola   +6 more
doaj   +1 more source

The Role of Keratin17 in Human Tumours

Frontiers in Cell and Developmental Biology, 2022
Keratins are a group of proteins that can constitute intermediate fibers. It is a component of the cytoskeleton and plays an important role in cell protection and structural support.
Hanqun Zhang, Yun Zhang, Tingting Xia, Liang Lu, Min Luo, Yanping Chen, Yuncong Liu, Yong Li   +7 more
doaj   +1 more source

WNT signaling regulates self-renewal and differentiation of prostate cancer cells with stem cell characteristics [PDF]

, 2009
Prostate cancer cells with stem cell characteristics were identified in human prostate cancer cell lines by their ability to form from single cells self-renewing prostaspheres in non-adherent cultures.
A de la Taille, A Glinka, A van Bokhoven, AA George, AP Verhagen, AS Waller, AT Collins, AT Collins, AT Collins, B Hoang, B Mao, BA Reynolds, C Lo Celso, C Wissmann, CC Carson 3rd, CI Truica, CL Hall, CL Hall, D Beier, D Bonnet, D Masiello, D Mizrak, DA Lawson, David M Prowse, DK Singla, DL Hudson, DL Hudson, DP Petrylak, DR Chesire, EM Hurt, G Dontu, G Gu, G Shaw, G Shaw, GD Richardson, GJ van Leenders, GL Shaw, GN Thalmann, H Clevers, H Li, H Zhu, HF English, Isabelle Bisson, IV Litvinov, IV Litvinov, J Miki, JA Schalken, JE Visvader, JM Adams, KD Bunting, KG Leong, L Adam, L Patrawala, L Patrawala, L Patrawala, L Ricci-Vitiani, L Vezzoni, L Xin, L Xin, LE Pascal, LG Wang, M Al-Hajj, M Locke, M Verras, MJ Linja, MS Chen, MS Wicha, N Uchida, PN Kelly, RI Bhatt, S Signoretti, S Weiss, S Zhou, SI Hwang, SK Singh, SM Janes, SV Shmelkov, T Hara, T Nikolova, T Reya, WJ Huss, Y Katoh, Y Lu   +82 more
core   +1 more source

Autophosphorylation at serine 166 regulates RIP kinase 1-mediated cell death and inflammation [PDF]

, 2020
Receptor interacting protein kinase 1 (RIPK1) regulates cell death and inflammatory responses downstream of TNFR1 and other receptors, and has been implicated in the pathogenesis of inflammatory and degenerative diseases.
Bertrand, Mathieu, Corona, Teresa, Delanghe, Tom, Kondylis, Vangelis, Krüger, Marcus, Kumari, Snehlata, Laurien, Lucie, Nagata, Masahiro, Pasparakis, Manolis, Schwarzer, Robin, Schünke, Hannah, Wiederstein, Janica L.   +11 more
core   +1 more source

Wool: From Properties and Structure to Genetic Insights and Sheep Improvement Strategies

Animals
The wool of sheep consists of structurally intricate natural fibres that can be processed and manufactured into a range of products. It is prized for its insulation, moisture-buffering capability, flame resistance, and biodegradability.
Huitong Zhou, Lingrong Bai, Shaobin Li, Jiqing Wang, Jon G. H. Hickford   +4 more
doaj   +1 more source

Comparative proteomic analysis in serum of former uranium miners with and without radon induced squamous lung cancer

Journal of Occupational Medicine and Toxicology, 2019
Summary Former uranium miners of the Wismut Company, East Germany, have been exposed to ionizing radiation from radon decay products and therefore were at high risk for lung cancer.
Simone Helmig, Günter Lochnit, Joachim Schneider   +2 more
doaj   +1 more source

Alopecia areata susceptibility variant in MHC region impacts expressions of genes contributing to hair keratinization and is involved in hair loss

EBioMedicine, 2020
: Background: Alopecia areata (AA) is considered a highly heritable, T-cell-mediated autoimmune disease of the hair follicle. However, no convincing susceptibility gene has yet been pinpointed in the major histocompatibility complex (MHC), a genome ...
Akira Oka, Atsushi Takagi, Etsuko Komiyama, Nagisa Yoshihara, Shuhei Mano, Kazuyoshi Hosomichi, Shingo Suzuki, Yuko Haida, Nami Motosugi, Tomomi Hatanaka, Minoru Kimura, Mahoko Takahashi Ueda, So Nakagawa, Hiromi Miura, Masato Ohtsuka, Masayuki Tanaka, Tomoyoshi Komiyama, Asako Otomo, Shinji Hadano, Tomotaka Mabuchi, Stephan Beck, Hidetoshi Inoko, Shigaku Ikeda   +22 more
doaj   +1 more source