Results 171 to 180 of about 139,965 (339)

Research progress of neurovascular units involved in ischemic stroke

open access: yesIbrain, EarlyView.
The brain receives less blood when an ischemic stroke develops, which damages neurons and leads to an increased release of Pro‐inflammatory mediators that activate neurovascular unit (NVU). When the tight junctions are broken and the basement membrane is disrupted by matrix metalloproteinases produced by active endothelial and pericellular cells ...
Yu Yang   +4 more
wiley   +1 more source

Apoptosis regulators of the Bcl‐2 family play a key role in chemoresistance of cholangiocarcinoma organoids

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Poor prognosis in cholangiocarcinoma (CCA) is attributed to late diagnosis and intrinsic chemoresistance. In particular, resistance mechanisms that suppress apoptosis limit the effectiveness of gemcitabine‐based regimens, which remain the standard treatment.
Wunan Mi   +7 more
wiley   +1 more source

Applications of bioactive herbal extracts in dressing materials for skin wound repair: Ingredients, mechanisms and innovations

open access: yesInterdisciplinary Medicine, EarlyView.
Abstract The skin, as the body's largest organ, plays essential roles in protection, immune regulation, and homeostasis. Skin trauma, especially chronic wounds such as diabetic ulcers, poses significant clinical challenges. Traditional treatments, while often effective, can be costly and pose risks.
Boxiang Yang   +12 more
wiley   +1 more source

Optomechanical Properties of Swine Skin Tissue Treated With a Nontoxic Optical Clearing Agent

open access: yesJournal of Biophotonics, EarlyView.
Experimental process to evaluate the optomechanical and structural properties of individual macroscopic layers in swine skin tissues treated with a nontoxic optical clearing agent. ABSTRACT This study evaluated the optomechanical and structural properties of individual macroscopic layers in swine skin tissues treated with a nontoxic optical clearing ...
Noemi Correa   +5 more
wiley   +1 more source

Proteomics Reveals Increased Periostin in Synovial Fluid From Canine and Human Anterior Cruciate Ligament Injury

open access: yesJournal of Orthopaedic Research, EarlyView.
ABSTRACT Posttraumatic osteoarthritis (PTOA) is a common sequela to anterior cruciate ligament (ACL) injury in humans and dogs. Identification of conserved targets between species may hasten biomarker identification and therapeutic development. To identify differentially regulated synovial fluid (SF) proteins in ACL injury, SF samples were collected ...
Sydney J. Womack   +4 more
wiley   +1 more source

Prevalence, incidence, risk, and protective factors for soft tissue dehiscences at implant sites in the absence of disease: An AO/AAP systematic review and meta‐regression analysis

open access: yesJournal of Periodontology, EarlyView.
Abstract Background The aim of the present review was to evaluate the prevalence and incidence of soft tissue dehiscences at implant sites in absence of disease, together with the related risk and protective factors. Methods A systematic search was conducted to identify cross‐sectional and prospective studies reporting information on soft tissue ...
Lorenzo Tavelli, Shayan Barootchi
wiley   +1 more source

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