Results 51 to 60 of about 91,815 (312)

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Anaerobic Process for Biohydrogen Production using Keratin Degraded Effluent

, 2019
Fossil fuel energy depletion and removal of environmental wastes are big problem in many countries. Some of the wastes contain a considerable amount of protein and carbon compounds; little concentration is given to utilizing or recycling these wastes ...
Muthuramalingam Jothi Basu, Gujuluva Hari Dinesh, Kulanthaisamy Mohanrasu, Ramu Satheesh Murugan, Alagarsamy Arun, Nagarajan Arumugam   +5 more
core   +1 more source

In-situ development of self-defensive antibacterial biomaterials: phenol-g-keratin-EC based bio-composites with characteristics for biomedical applications [PDF]

, 2015
Recently, the development of highly inspired biomaterials with multi-functional characteristics has gained considerable attention, especially in biomedical, and other health-related areas of the modern world.
Kyazze, G., Godfrey Kyazze, Tajalli Keshavarz, Keshavarz, T., Thierry Tron, Iqbal, H.M.N., Ian Charles Locke, Hafiz M. N. Iqbal, Tron, T., Locke, I.C.   +9 more
core   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source

Determination of Keratinase Activity using Chicken Feather DMSO extract and its optimization with Response Surface Methodology [PDF]

E3S Web of Conferences
Keratinase is an enzyme capable of degrading keratin, exhibiting two activities: protease activity, which cleaves peptide bonds, and disulfide reductase activity, which reduces disulfide bonds (-S-S-). However, keratinase activity is often measured using
Rizqi Maharani Fazria, Suharti Suharti
doaj   +1 more source

How keratin cortex thickness affects iridescent feather colours

Royal Society Open Science, 2023
The bright, saturated iridescent colours of feathers are commonly produced by single and multi-layers of nanostructured melanin granules (melanosomes), air and keratin matrices, surrounded by an outer keratin cortex of varying thicknesses.
Deok-Jin Jeon, Seungmuk Ji, Eunok Lee, Jihun Kang, Jiyeong Kim, Liliana D'Alba, Marie Manceau, Matthew D. Shawkey, Jong-Souk Yeo   +8 more
doaj   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

One-Pot Synthesis of Chicken-Feather-Keratin-Based Prodrug Nanoparticles with High Drug Content for Tumor Intracellular DOX Delivery

, 2019
pH/reduction dual-triggered chicken-feather-keratin-based prodrug nanoparticles (C-PK/-SS-Hy-D NPs) were designed via a facile one-pot oxidation coupling reaction between the thiol-functional acid-labile prodrug M-Hy-D and the PEGylated keratin (PK ...
Peng Liu (120506), Huifang Zhang, Peng Liu, Huifang Zhang (283360)   +3 more
core   +1 more source

One-pot process: Microwave-assisted keratin extraction and direct electrospinning to obtain keratin-based bioplastic [PDF]

, 2021
Poultry feathers are among the most abundant and polluting keratin-rich waste bio-masses. In this work, we developed a one-pot microwave-assisted process for eco-friendly keratin extraction from poultry feathers followed by a direct electrospinning (ES ...
Pelosi C., Bramanti E., Bernazzani L., Pulidori E., De Acutis A., Duce C., Montemurro F., Vozzi G., Tine M. R., Micalizzi S., De Maria C.   +10 more
core   +1 more source

Strain‐Programmable Luminescent Adhesive Patch With Tartrazine‐Mediated Optical Skin Clearing for Photochemical Tissue Bonding

Advanced Functional Materials, EarlyView.
We propose a suture‐complementary approach that integrates optical skin clearing with a strain‐programmable luminescent adhesive patch. Hyaluronic acid promotes transdermal delivery of tartrazine to improve optical clearing and stabilizes its interaction with a photosensitizer. Optical clearing increases the penetration depth of visible light into skin,
Seong‐Jong Kim, Kyungjoo Jo, Kwanghyeon Park, Jun Hee Kim, Jong Hyeong Cho, Inhoo Choi, Sei Kwang Hahn   +6 more
wiley   +1 more source