Results 71 to 80 of about 78,262 (265)

Synthese und aktivitätsbasierte Proteinprofilierung identifizieren die Aldo‐Keto‐Reduktase 1C3 als Zielprotein der Myxoglucamide

Angewandte Chemie, EarlyView.
Myxoglucamid A – ein neuartiges, aus Myxobakterien isoliertes Glykolipopeptid – wurde erstmals totalsynthetisch hergestellt. Mittels aktivitätsbasierter Proteinprofilierung (ABPP) wurde die Aldo‐Keto‐Reduktase 1C3 (AKR1C3) als primäres Zielprotein in menschlichen Zellen identifiziert.
Thomas Siemon, Vivek K. Mishra, Mingming Zhao, Konrad Büssow, Alexander Popoff, Chengzhang Fu, Rolf Müller, Lothar Jänsch, Wulf Blankenfeldt, Mark Brönstrup   +9 more
wiley   +1 more source

Extraction of Keratin from Chicken Feathers and its Application in the Treatment of Contaminated Water: an Eco-Friendly Approach

Brazilian Archives of Biology and Technology
Chicken feathers that make up 4-6% of total weight of chicken are most influential waste by-product from poultry farm and slaughter. Annual worldwide generation of several tons of feather biomass raise solid waste management concerns.
Sumaira Amin, Moneeza Abbas, Houda Javed, Zahra Asghar, Nadia Ghani, Shabnum Shaheen, Faiza Hassan, Rabia Akram, Hafiza Sana Yousaf   +8 more
doaj   +1 more source

The Expression of Keratin 19 in Intervertebral Disc Degeneration and Aging

Global Spine Journal, 2016
Introduction Low back pain (LBP) affects 80% of the whole population around the world and causes great social-economic burden. Intervertebral disc (IVD) degenerates with aging and is a major contribution to LBP.
Fengjuan Lv, Victor Y. L. Leung, Kenneth M. C. Cheung   +2 more
doaj   +1 more source

Synthesis and Activity‐Based Protein Profiling Identifies Aldo‐Keto Reductase 1C3 as Target Protein of Myxoglucamides

Angewandte Chemie International Edition, EarlyView.
Myxoglucamide A—a novel glycolipopeptide isolated from myxobacteria—was synthesized, and activity‐based protein profiling identified aldo‐keto reductase 1C3 (AKR1C3) as its main target in human cells. Structure‐activity relationship studies, together with biophysical characterization and X‐ray crystallography, elucidated the structural basis of AKR1C3 ...
Thomas Siemon, Vivek K. Mishra, Mingming Zhao, Konrad Büssow, Alexander Popoff, Chengzhang Fu, Rolf Müller, Lothar Jänsch, Wulf Blankenfeldt, Mark Brönstrup   +9 more
wiley   +1 more source

Inverse Vulcanized Sulfur Polymer Composites From Poultry‐Industry Products and Lignocellulosic Biomass Waste

Journal of Applied Polymer Science, EarlyView.
This work explores the use of various fillers, including eggshell powder, feather meal, peanut hulls, and sawdust to reinforce a base binder GFS90 (comprised of 90 wt.% sulfur, 5 wt.% chicken fat, and 5 wt.% sunflower oil). The resulting composites showed impressive compressive strengths ranging from 15.3 to 36.2 MPa, making them a potential ...
Bárbara G. S. Guinati, Katelyn A. Tisdale, Rashmi N. Jayasinghe, Nicholas B. Ames, Ashlyn D. Smith, Rhett C. Smith   +5 more
wiley   +1 more source

Design Considerations for Polymer–Deep Eutectic Solvent Hybrid Systems for Transdermal Drug Delivery

Journal of Applied Polymer Science, EarlyView.
Deep eutectic solvents (DESs) act as tunable, green excipients that modulate polymer structure–property relationships to enhance drug solubility, skin permeation, stability, and controlled release. Through hydrogen‐bond interactions, DES–polymer hybrid systems enable improved transdermal performance, offering a rational, design‐driven platform for ...
Madhavi Kailas Kapale, Madhur Kulkarni, Pranav J. Shah, Furqan A. Maulvi   +3 more
wiley   +1 more source

Synthesis and Characterization of Keratin-Based Scaffold for Potential Tissue Engineering Applications

Fibers
Keratin, a fibrous structural protein, has been employed as a biomaterial for hemostasis and tissue repair due to its structural stability, mechanical strength, biocompatibility, and biodegradability.
Murugiah Krishani, Jia Ning Chong, Wan Rong Lim, Norwahyu Jusoh, Nonni Soraya Sambudi, Hazwani Suhaimi   +5 more
doaj   +1 more source

Porous Poly(ε‐Caprolactone)/Keratin Composite Scaffolds: Structural Features, Degradation Behavior and Cell‐Material Interactions

Journal of Applied Polymer Science, EarlyView.
ABSTRACT Porous scaffolds based on pure poly(ε‐caprolactone) (PCL) and on biocomposite made of PCL and feather‐extracted β‐keratin (FK) were fabricated by salt‐leaching method. FK was incorporated into PCL to address the limited bioactivity and hydrophobic nature of PCL, with the aim of improving cell–material interactions for bone tissue engineering ...
Gianluca Rinaldi, Nancy Ferrentino, Martina Mucciolo, Valentina Sessini, Marina Paolucci, Elena Coccia, Daniela Pappalardo   +6 more
wiley   +1 more source

Re‐evaluation of a soft crested Edmontosaurin, with implications for hadrosaurid life appearance and diversity

The Anatomical Record, EarlyView.
Abstract Hadrosaurid dinosaurs are generally regarded as “crested” or “non‐crested” depending on the presence or absence of a bony cranial crest. At least one supposedly “non‐crested” hadrosaur is known to have possessed a soft tissue cranial crest (or comb), based on an exceptionally preserved “mummified” specimen. Here we redescribe this specimen and
Henry S. Sharpe, Phil R. Bell, Ian Baylatry, Robin Sissons, Corwin Sullivan   +4 more
wiley   +1 more source

Bite force estimates and morphological correlations of jaw muscles in parrots

The Anatomical Record, EarlyView.
Abstract Parrots (Order: Psittaciformes) are renowned for their high bite force (BF) and morphological correlates thereof, including a highly mobile skull and two unique mandibular adductor muscles—m. pseudomasseter and m. ethmomandibularis, with the former being hypothesized to increase force output.
Ana Carolina L. Faillace, Arin Berger, Marcelo Ismar S. Santana, Adam Hartstone‐Rose   +3 more
wiley   +1 more source