Results 61 to 70 of about 91,815 (312)

Proteolytic and non-proteolytic mechanisms of keratin degradation in Onygena corvina revealed by a proteogenomic approach

Applied and Environmental Microbiology
Keratin-rich by-products from the poultry, textile, and leather industries pose a significant challenge for sustainable waste management due to their highly recalcitrant nature.
Siddhi Pavale, Clémentine Isembart, Volha Shapaval, Tina R. Tuveng, Sabina Leanti La Rosa, Vincent G. H. Eijsink   +5 more
doaj   +1 more source

Self‐Assembled Skin Equivalents with Monoclonal CRISPR/Cas9‐Modified N/TERT‐1 Keratinocytes: A Cutting‐Edge model for Human Skin and its Diseases

Advanced Healthcare Materials, EarlyView.
Self‐assembled, scaffold‐free full‐thickness skin equivalents with monoclonal, genetically modified N/TERT‐1 keratinocytes represent a novel in vitro model of human skin and skin diseases. The model is highly robust, reproducible, physiologically relevant, and suitable for high‐throughput applications.
Marta Slaufova, Tugay Karakaya, Michela Di Filippo, Thomas Kündig, Hans‐Dietmar Beer   +4 more
wiley   +1 more source

The comparative analysis of the methods for keratin extraction from sheep wool and human hair

, 2020
Nowadays, biopolymers such as keratins are widely used in biomedicine due to their low toxicity, biocompatibility, and biodegradability. At the molecular level, keratins differ from other structural proteins by a high content of disulfide bonds, which ...
V. Mykhaliuk, V. Havryliak
core   +1 more source

Hydrogel‐Based Airway‐on‐Tube With Perfusable Endothelial Lumen and Outward Epithelialization

Advanced Materials, EarlyView.
A hydrogel‐based airway‐on‐tube platform featuring a perfusable endothelial lumen and outward epithelialization is presented. The system supports primary human bronchial epithelial and lung microvascular endothelial coculture under air‐liquid interface conditions.
Ali Doryab, Jack F. Murphy, Michael Bartolf‐Kopp, Jenny C‐C Hsin, Alice Chernaik, Frank McCaughan, Yan Yan Shery Huang, Tomasz Jungst, Jürgen Groll   +8 more
wiley   +1 more source

Effect of Extraction Method on the Structure and Performance of Keratin Hydrogel

Pige Kexue Yu Gongcheng
Keratin-based hydrogels have been used more and more in the fields of biomedical materials and cosmetics. However, there are obvious differences in the molecular weight and its distribution as well as the content of active sulfhydryl groups of keratin ...
Xin LI, Die ZOU, Haiming CHENG
doaj   +1 more source

Two Routes to Land: Genomic Underpinnings of Parallel Aerial Egg Deposition in Aquatic Old‐World Pila and New‐World Pomacea (Ampullariidae)

Advanced Science, EarlyView.
Comparative genomics of Gondwana‐diverged Pila and Pomacea reveals parallel evolution of aerial oviposition. Convergent chromosomal rearrangements reshape regulatory landscapes within topologically associating domains. Lineage‐specific gene family expansions and viral‐derived perivitelline proteins (PV1) underpin desiccation resistance.
Yufei Zhou, Huawei Mu, Xueying Nie, Yue Gao, Hui Wang, Ling Fang, Tiangang Luan, Monthon Ganmanee, Jian‐Wen Qiu, Jin Sun, Jack Chi‐Ho Ip   +10 more
wiley   +1 more source

Eif3k Regulates Apoptosis in Epithelial Cells by Releasing Caspase 3 from Keratin-Containing Inclusions

, 2009
Keratins 8 and 18 (collectively referred to as K8/K18) are the major components of intermediate filaments of simple epithelial cells. Recent studies have revealed the function of K8/K18 in apoptosis modulation.
林裕敏;王琬菁;吳益群;陳瑞華, Lin, Y.-M.; Chen, Y.-R.; Lin, J.-R.; Wang, W.-J.; Inoko, A.; Inagaki, M.; Wu, Y.-C.; Chen, R.-H.   +1 more
core   +1 more source

MEOX1 Coordinates Autocrine‐Paracrine Programs via SPHK1/S1P to Promote Lymph Node Metastasis in Ovarian Cancer

Advanced Science, EarlyView.
In ovarian cancer, MEOX1 activates the SPHK1/S1P pathway to promote both tumor progression and tumor–stroma crosstalk. MEOX1‐dependent signaling drives CAF activation, enhances VEGF‐C expression, and stimulates lymphangiogenesis, ultimately facilitating lymph node metastasis.
Jiajia Li, Xiuling Zhi, Qianhan Lin, Yating Sun, Yihua Sun, Zulimire Abudousalamu, Mengyang Xue, Chang Zheng, Xiaotian Li, Liangqing Yao, Mo Chen   +10 more
wiley   +1 more source

Highly Efficient Dissolution of Wool Keratin by Dimethylphosphate Ionic Liquids

, 2015
Ionic liquids (ILs) are eco-friendly solvents and exhibit excellent performance for dissolution and regeneration of wool keratin. In this work, a series of ILs are designed and synthesized to investigate effects of IL structures on dissolving wool ...
Zhang, Xiangping, Lijun Wang (176511), Wang, Lijun, Suojiang Zhang (1235670), Nie, Yi, Zhang, Suojiang, Yi Nie (1498129), Zheng, Shuangshuang, Xiangping Zhang (1365345), Shuangshuang Zheng (471780)   +9 more
core   +1 more source

Keratin intermediate filaments in the colon: guardians of epithelial homeostasis

, 2020
Keratin intermediate filament proteins are major cytoskeletal components of the mammalian simple layered columnar epithelium in the gastrointestinal tract.
Heikkil�, Taina, Tayyab, Mina, Baghestani, Sarah, Toivola, Diana M., Nystr�m, Joel H., Alam, Catharina M., Polari, Lauri   +6 more
core   +1 more source