Results 101 to 110 of about 56,636 (187)

Loss of Keratin 19 predisposes to the development of cholestatic liver disease

open access: yes, 2014
Keratins (K) are cytoprotective proteins and keratin mutations predispose to development of multiple human diseases. K19 represents the most widely used biliary and liver progenitor cell (LPC) marker. Since K19 variants were found in patients with primary biliary cirrhosis (PBC), we investigated the role of K19 in cholangiocytes and LPCs. K19 wild-type
openaire   +2 more sources

Clinical significance of bone marrow micrometastasis detected by nested rt-PCR for keratin-19 in breast cancer patients.

open access: yes, 2003
PURPOSE: Breast cancers in the early phase frequently undergo distant metastasis and survival of patients is greatly dependent on distant metastasis. The occurrence of micrometastasis has been suggested to relate with prognostic features of breast cancer,
Kim, HJ   +7 more
core  

Plasma Proteomics Elucidated a Protein Signature in COVID-19 Patients with Comorbidities and Early-Diagnosis Biomarkers

open access: yesBiomedicines
Despite great scientific efforts, deep understanding of coronavirus-19 disease (COVID-19) immunopathology and clinical biomarkers remains a challenge. Pre-existing comorbidities increase the mortality rate and aggravate the exacerbated immune response ...
Víctor Urbiola-Salvador   +4 more
doaj   +1 more source

K15 & Id3 expression in intact and regenerating adult vibrissae rodent hair follicles [PDF]

open access: yes, 2009
The hair follicle can renew itself through an intrinsic stem cell population and has the ability to undergo hair follicle growth cycle; its regenerative activities under normal and experimental conditions together with a feature of easy access make it an
Chen, Bo
core  

Cytokeratin expression in breast cancer: from mechanisms, progression, diagnosis, and prognosis to therapeutic implications

open access: yesMolecular & Cellular Oncology
Background and Aim Cytokeratins (CKs) are structural proteins vital to epithelial integrity and play key roles in breast cancer progression. This review explores their expression, functions, and therapeutic potential.Methods A systematic review was ...
Ensiyeh Bahadoran   +8 more
doaj   +1 more source

Evidence for Novel Functions of the Keratin Tail Emerging from a Mutation Causing Ichthyosis Hystrix

open access: yes, 2001
Unraveling the molecular basis of inherited disorders of epithelial fragility has led to understanding of the complex structure and function of keratin intermediate filaments. Keratins are organized as a central α-helical rod domain flanked by nonhelical,
Becker, Oren M.   +7 more
core   +1 more source

Development and evaluation of an immunoassay for Keratin 5/19 complex in lung cancer

open access: yes, 2015
14 antibody combinations were evaluated as candidates for a keratin 5/19 enzymeimmunoassay. By enzyme immune assay and western blot, 1A12+Ks19.1 was determined as the superior combination.
Andersson, Sofia
core   +2 more sources

Biofibre Production from Chicken Feather

open access: yes, 2011
The global poultry industry generates at least 2 million tonnes of chicken feather every year. Feathers are currently hydrolysed into meal used for animal feed and fertilizer. Feather consists of 91% keratin, 1% lipid and 8% water.
Tseng, Fan-Chen Jeanie
core  

Home - About - Disclaimer - Privacy