Results 51 to 60 of about 5,007,555 (282)

MCF-7 Human Breast Cancer Cells Form Differentiated Microtissues in Scaffold-Free Hydrogels.

open access: yesPLoS ONE, 2015
Three-dimensional (3D) cultures are increasing in use because of their ability to represent in vivo human physiology when compared to monolayer two-dimensional (2D) cultures.
Marguerite M Vantangoli   +4 more
doaj   +1 more source

Upcycling Keratin‐Based Textile Waste Into High‐Performance Hybrid Fibers Via Tuning the Interfacial Interactions

open access: yesAdvanced Functional Materials, EarlyView.
Keratin recovered from animal‐hair textile waste is fractionated and blended with cellulose to produce continuously spun hybrid fibers. Selecting the high‐molecular‐weight keratin fraction enables 30 wt.% keratin incorporation while maintaining high strength in dry and wet states.
Mian Zhai   +6 more
wiley   +1 more source

Lung Cancer-Associated Keratin 19 Fragments: Development and Biochemical Characterisation of the New Serum Assay Enzymun-Test Cyfra 21–1

open access: yesThe International Journal of Biological Markers, 1994
From a panel of 4 murine monoclonal antibodies directed against keratin 19 various antibody combinations were evaluated in solid-phase enzyme-linked sandwich immunoassays for detection of soluble keratin 19 fragments in patient sera.
H. Bodenmüller   +5 more
doaj   +1 more source

Detection of lymph node metastasis in lung cancer patients using a one-step nucleic acid amplification assay: a single-centre prospective study

open access: yesJournal of Translational Medicine, 2019
Background The use of one-step nucleic acid amplification (OSNA) allows for lymph node (LN) metastasis to be detected rapidly and accurately. We conducted a prospective single-centre clinical trial to evaluate OSNA assay in detecting LN metastasis of ...
María Escalante Pérez   +6 more
doaj   +1 more source

Cross-talk between microRNA-let7c and transforming growth factor-β2 during epithelial-to-mesenchymal transition of retinal pigment epithelial cells [PDF]

open access: yesInternational Journal of Ophthalmology, 2020
AIM: To explore the roles of microRNA-let7c (miR-let7c) and transforming growth factor-β2 (TGF-β2) and cellular signaling during epithelial-to-mesenchymal transition (EMT) of retinal pigment epithelial cells. METHODS: Retinal pigment epithelial (ARPE-19)
Qu-Zhen Deji   +5 more
doaj   +1 more source

Keratin-Templated Synthesis of Metallic Oxide Nanoparticles as MRI Contrast Agents and Drug Carriers

open access: yes, 2018
Keratin is a family of cysteine-rich structural fibrous proteins abundantly present in skin and skin appendages. Inspired by the template synthesis strategy, in this work, keratin was utilized for the first time as a platform template to synthesize ...
Chen Peng (429537)   +4 more
core   +1 more source

Hydrogel‐Based Airway‐on‐Tube With Perfusable Endothelial Lumen and Outward Epithelialization

open access: yesAdvanced Materials, EarlyView.
A hydrogel‐based airway‐on‐tube platform featuring a perfusable endothelial lumen and outward epithelialization is presented. The system supports primary human bronchial epithelial and lung microvascular endothelial coculture under air‐liquid interface conditions.
Ali Doryab   +8 more
wiley   +1 more source

Immune Cells Profiles in the Different Sites of COVID-19-Affected Lung Lobes in a Single Patient

open access: yesFrontiers in Medicine, 2022
Whereas the COVID-19 disease pathophysiology is under investigation, it is important to identify the pathways of viral transmission and inflammation from the pre-illness to the disease-onset stages.
Sadahiro Iwabuchi   +8 more
doaj   +1 more source

A Ca2+-Mediated Switch of Epiplakin from a Diffuse to Keratin-Bound State Affects Keratin Dynamics

open access: yes, 2022
Keratins exert important structural but also cytoprotective functions. They have to be adaptable to support cellular homeostasis. Epiplakin (EPPK1) has been shown to decorate keratin filaments in epithelial cells and to play a protective role under ...
Rudolf E. Leube   +9 more
core   +1 more source

Keratin–Melanin Complexation Enables Robust, Delamination‐Resistant Feather‐Inspired Structural Color Coatings for Flexible and Curved Substrates

open access: yesAdvanced Materials Interfaces, EarlyView.
Providing mechanically robust structural color coating technology inspired by cooperative interactions in nature. The spatial arrangement of melanin particles within the keratin matrix generates angle‐independent structural colors. Diverse functional groups in keratin and melanin contribute to interparticle and substrate adhesion, resulting in the ...
Taisei Harada   +12 more
wiley   +1 more source

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