Results 91 to 100 of about 5,007,555 (282)

The interaction between the HPV E1^E4 protein and the cell cytoskeleton. [PDF]

open access: yes, 2007
Papillomaviruses are small DNA viruses, which cause benign and malignant lesions in the differentiated epithelium of mammals and birds. A small subset of human papillomaviruses (HPV's), have been identified as the etiological agent of cervical cancer ...
Laskey, P.
core  

Temporal Trajectories of the Tau Aggregate Interactome Reveal Stage‐Specific Vulnerabilities in Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
Tau populations with different aggregation states associate with distinct sets of proteins in the Alzheimer's disease brain. Proteomic discovery combined with single‐molecule analysis in neurons reveals dynamic associations involving proteostasis, metabolism and RNA biology.
Dorothea Böken   +8 more
wiley   +1 more source

Synthese und aktivitätsbasierte Proteinprofilierung identifizieren die Aldo‐Keto‐Reduktase 1C3 als Zielprotein der Myxoglucamide

open access: yesAngewandte Chemie, EarlyView.
Myxoglucamid A – ein neuartiges, aus Myxobakterien isoliertes Glykolipopeptid – wurde erstmals totalsynthetisch hergestellt. Mittels aktivitätsbasierter Proteinprofilierung (ABPP) wurde die Aldo‐Keto‐Reduktase 1C3 (AKR1C3) als primäres Zielprotein in menschlichen Zellen identifiziert.
Thomas Siemon   +9 more
wiley   +1 more source

A Keratin-Waste Derived Multifunctional Gel System: Reusable Activated Carbon/Alginate Microbeads for Simultaneous Dye and Pharmaceutical Adsorption

open access: yesGels
The resource utilization of keratin waste has garnered significant attention, yet the processing of yak hair keratin in underdeveloped regions such as Tibet and Qinghai in China remains challenging.
Yue Wang   +7 more
doaj   +1 more source

Anaerobic Process for Biohydrogen Production using Keratin Degraded Effluent

open access: yes, 2019
Fossil fuel energy depletion and removal of environmental wastes are big problem in many countries. Some of the wastes contain a considerable amount of protein and carbon compounds; little concentration is given to utilizing or recycling these wastes ...
Muthuramalingam Jothi Basu   +5 more
core   +1 more source

Synthesis and Activity‐Based Protein Profiling Identifies Aldo‐Keto Reductase 1C3 as Target Protein of Myxoglucamides

open access: yesAngewandte Chemie International Edition, EarlyView.
Myxoglucamide A—a novel glycolipopeptide isolated from myxobacteria—was synthesized, and activity‐based protein profiling identified aldo‐keto reductase 1C3 (AKR1C3) as its main target in human cells. Structure‐activity relationship studies, together with biophysical characterization and X‐ray crystallography, elucidated the structural basis of AKR1C3 ...
Thomas Siemon   +9 more
wiley   +1 more source

One-Pot Synthesis of Chicken-Feather-Keratin-Based Prodrug Nanoparticles with High Drug Content for Tumor Intracellular DOX Delivery

open access: yes, 2019
pH/reduction dual-triggered chicken-feather-keratin-based prodrug nanoparticles (C-PK/-SS-Hy-D NPs) were designed via a facile one-pot oxidation coupling reaction between the thiol-functional acid-labile prodrug M-Hy-D and the PEGylated keratin (PK ...
Peng Liu (120506)   +3 more
core   +1 more source

Envoplakin, a novel precursor of the cornified envelope that has homology to desmoplakin [PDF]

open access: yes, 1996
The cornified envelope is a layer of transglutaminase cross-linked protein that is deposited under the plasma membrane of keratinocytes in the outermost layers of the epidermis.
Dooley, TP   +9 more
core   +1 more source

Bite force estimates and morphological correlations of jaw muscles in parrots

open access: yesThe Anatomical Record, EarlyView.
Abstract Parrots (Order: Psittaciformes) are renowned for their high bite force (BF) and morphological correlates thereof, including a highly mobile skull and two unique mandibular adductor muscles—m. pseudomasseter and m. ethmomandibularis, with the former being hypothesized to increase force output.
Ana Carolina L. Faillace   +3 more
wiley   +1 more source

The correlation between poor prognosis and increased yes-associated protein 1 expression in keratin 19 expressing hepatocellular carcinomas and cholangiocarcinomas

open access: yesBMC Cancer, 2017
Background The Hippo pathway plays a vital role in liver regeneration and development by determining cellular lineage and regulating cell proliferation and apoptosis.
KyuHo Lee   +6 more
doaj   +1 more source

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