Results 71 to 80 of about 57,590 (253)
Advanced Science, EarlyView.A novel geometry‐resolved membrane platform provides a seamlessly integrated pipeline for studying curvature‐sensing proteins. By linking shotgun proteomics with quantitative imaging, this approach enables both the unbiased discovery and rigorous validation of novel sensors across the entire curvature range—positive, negative, and zero.
Takumi Komikawa +6 more
wiley +1 more source
ANTIFUNGAL EFFECT OF GOLD NANOPARTICLES ON FUNGI ISOLATED FROM ONYCHOMYCOSIS PATIENTS [PDF]
Al-Azhar Journal of Pharmaceutical Sciences, 2019 Onychomycosis is a widely distributed fungal nail infection which can be caused by dermatophytes, yeasts or non-dermatophytic fungi. In our study a total of 7 species related to 4 genera were isolated from 50 patients suspected with the fungal nail ...
Aml Sami
doaj +1 more source
Chicken keratin‐19: Cloning of cDNA and analysis of expression in the chicken embryonic gut [PDF]
Development, Growth & Differentiation, 1997 From many recent studies, it has been argued that keratins (cytokeratins) play important roles in the morphogenesis and differentiation of organ development. To learn the role of keratin in digestive tract development, a cDNA of the chicken homolog of keratin‐19 (GK‐19) was cloned and its expression pattern was analyzed in the digestive tract of ...
K, Sato, S, Yasugi
openaire +2 more sources
Advanced Science, EarlyView.Tau populations with different aggregation states associate with distinct sets of proteins in the Alzheimer's disease brain. Proteomic discovery combined with single‐molecule analysis in neurons reveals dynamic associations involving proteostasis, metabolism and RNA biology.
Dorothea Böken +8 more
wiley +1 more source
Novel Picornavirus Associated with Avian Keratin Disorder in Alaskan Birds
mBio, 2016 Avian keratin disorder (AKD), characterized by debilitating overgrowth of the avian beak, was first documented in black-capped chickadees (Poecile atricapillus) in Alaska.
Maxine Zylberberg +5 more
doaj +1 more source
Surgical and Experimental Pathology, 2023 Introduction Extraskeletal osteosarcoma arising in the penis is exceedingly rare and its major differential diagnosis is sarcomatoid carcinoma. Case presentation A 19-year-old patient noticed a deep nodule in the dorsal side of the penis 2 years before ...
Daniel Abensur Athanazio +3 more
doaj +1 more source
Advanced Science, EarlyView.Hypertrophic scar fibroblasts membrane‐hybridized cationic transfersomes enable efficient loading and transdermal delivery of TGF‐β1 siRNA through multiple skin penetration pathways. The biomimetic platform enhances homotypic targeting, transfection, and immune evasion, suppresses TGF‐β1‐driven fibrotic signaling, and reduces extracellular matrix ...
Hui Xing +9 more
wiley +1 more source
Advanced Science, EarlyView.An advanced, long‐term human skin platform maintains native skin structure and key tissue functions for up to four weeks. The platform models chronic inflammation, aging‐related skin changes, and UVB damage, enabling drug and topical interventions—including anti‐inflammatory therapy, senolytic treatment, and sunscreen—to be evaluated in intact human ...
Purnendu Kumar Sharma +14 more
wiley +1 more source
The pancreatic and duodenal homeobox protein PDX-1 regulates the ductal specific keratin 19 through the degradation of MEIS1 and DNA binding. [PDF]
PLoS ONE, 2010 Pancreas organogenesis is the result of well-orchestrated and balanced activities of transcription factors. The homeobox transcription factor PDX-1 plays a crucial role in the development and function of the pancreas, both in the maintenance of ...
Johannes von Burstin +3 more
doaj +1 more source
Advanced Science, EarlyView.OSMR mutations disrupt STAT5 signaling and AKR1B10‐mediated lipid metabolism, leading to lipid accumulation and protein aggregation in keratinocytes. This metabolic reprogramming drives amyloid deposition in primary localized cutaneous amyloidosis, revealing a mechanistic link between lipid dysregulation and amyloidogenesis.
Huiting Liu +8 more
wiley +1 more source