Results 11 to 20 of about 56,112 (250)

Keratin as a Potential Prognostic Biomarker for Breast Cancer Progression: An Evidence-Synthesizing Narrative Review [PDF]

Breast Cancer: Targets and Therapy
Astrid Feinisa Khairani,1 Karina Fitria Alhaq,2 Regina Indrasari Herriyanto,2 Mh Busra Fauzi,3 Nayla Majeda Alfarafisa1 1Department of Biomedical Sciences, Faculty of Medicine, Universitas Padjadjaran, Bandung, West Java, Indonesia; 2Faculty of Medicine,
Khairani AF, Alhaq KF, Herriyanto RI, Fauzi MB, Alfarafisa NM   +4 more
doaj   +2 more sources

Keratin 19 is a potential diagnostic and prognostic biomarker in pancreatic adenocarcinoma. [PDF]

Medicine (Baltimore)
This study aimed to evaluate Keratin 19 (KRT19) as a potential prognostic biomarker for the diagnosis and prognosis of pancreatic adenocarcinoma (PAAD). Using data from The Cancer Genome Atlas and the Gene Expression Omnibus, we analyzed KRT19 expression in PAAD tissues and identified differentially expressed genes associated with KRT19. Gene ontology (
He L, Li L, Chen Z, Chen Z.
europepmc   +3 more sources

Signal peptide-independent secretion of keratin-19 by pancreatic cancer cells. [PDF]

Proc Natl Acad Sci U S A
Abstract The exclusion of T cells causes immune escape of pancreatic ductal adenocarcinoma (PDA). T cell exclusion is mediated by the interaction between CXCR4 on T cells and its ligand, CXCL12, which is complexed to keratin-19 (KRT19) on the surface of PDA cells.
Moresco P, Kastan JP, Yang JI, Prabakar R, Kelley ZL, Minicozzi F, Adams DW, Cifani P, Tuveson DA, Fearon DT.   +9 more
europepmc   +5 more sources

Improving the Adsorption Properties of Keratin-Based Goat Hair Toward Reactive Dyes in Dyeing Wastewater by Steam Explosion

Journal of Natural Fibers, 2023
Keratin-based goat hair could be used bioadsorbent due to its large availability, biodegradability and low cost. Unfortunately, most available keratin adsorbents are either low in adsorption capacity or high in preparation cost.
Shijin Wei, Xiuliang Hou, Linyun Liu, Yue Tian, Wei Li, Helan Xu   +5 more
doaj   +1 more source

Efficient isolation of keratin from protein-rich waste biomass: a practical approach to minimize environmental impact and valorize waste biomass

Sustainable Environment Research, 2022
Among various protein-containing biomass wastes, waste animal wool, poultry feather, and human hair are considered one of the most important renewable sources of keratin.
Tapan Kumar Maity, Nripat Singh, Pradipkumar Vaghela, Arup Ghosh, Sanju Singh, Pramod B. Shinde, Rosy Alphons Sequeira, Kamalesh Prasad   +7 more
doaj   +1 more source

Keratin 19: a key role player in the invasion of human hepatocellular carcinomas [PDF]

Gut, 2013
Objective Keratin (K)19, a biliary/hepatic progenitor cell (HPC) marker, is expressed in a subset of hepatocellular carcinomas (HCC) with poor prognosis. The underlying mechanisms driving this phenotype of K19-positive HCC remain elusive. Design
Govaere, Olivier, Komuta, M.Ina, Berkers, Joost, Spee, Bart, Janssen, Carl, de Luca, Francesca, Katoonizadeh, Aezam, Wouters, Jasper, van Kempen, Léon C., Durnez, Anne, Verslype, Chris, De Kock, Joery, Rogiers, Vera, van Grunsven, Leo A., Topal, Baki, Pirenne, Jacques, Vankelecom, Hugo, Nevens, Frederik, van den Oord, Joost, Pinzani, Massimo, Roskams, Tania   +20 more
openaire   +7 more sources

No difference in keratin thickness between inner and outer foreskins from elective male circumcisions in Rakai, Uganda. [PDF]

PLoS ONE, 2012
It has been hypothesized that increased HIV acquisition in uncircumcised men may relate to a more thinly keratinized inner foreskin. However, published data are contradictory and potentially confounded by medical indications for circumcision.
Minh H Dinh, Taha Hirbod, Godfrey Kigozi, Eneniziaogochukwu A Okocha, Gianguido C Cianci, Xiangrong Kong, Jessica L Prodger, Kristina Broliden, Rupert Kaul, David Serwadda, Maria J Wawer, Ronald H Gray, Thomas J Hope   +12 more
doaj   +1 more source

Keratin 19 Epithelial Patterns in Cirrhotic Stroma Parallel Hepatocarcinogenesis [PDF]

The American Journal of Pathology, 2011
Cirrhotic septa harbor vessels and inflammatory, fibrogenic, and ductular epithelial cells, collectively referred to as the ductular reaction (DR). Lack of the DR in the stromal compartment around hepatocellular carcinoma (HCC) has been documented; however, the relationship of epithelial keratin 19 (K19) structures to progression of intralesional ...
Jochen K M, Lennerz, William C, Chapman, Elizabeth M, Brunt   +2 more
openaire   +2 more sources

An Integrative Bioinformatic Analysis for Keratinase Detection in Marine-Derived Streptomyces

Marine Drugs, 2021
Keratinases present promising biotechnological applications, due to their ability to degrade keratin. Streptomyces appears as one of the main sources of these enzymes, but complete genome sequences of keratinolytic bacteria are still limited.
Ricardo Valencia, Valentina González, Agustina Undabarrena, Leonardo Zamora-Leiva, Juan A. Ugalde, Beatriz Cámara   +5 more
doaj   +1 more source

Keratin 13 is a more specific marker of conjunctival epithelium than keratin 19.

Molecular vision, 2011
To evaluate the expression patterns of cytokeratin (K) 12, 13, and 19 in normal epithelium of the human ocular surface to determine whether K13 could be used as a marker for conjunctival epithelium.Total RNA was isolated from the human conjunctiva and central cornea.
Ramirez-Miranda, Arturo, Nakatsu, Martin N, Zarei-Ghanavati, Siamak, Nguyen, Christine V, Deng, Sophie X   +4 more
openaire   +3 more sources