Results 81 to 90 of about 57,119 (251)

Age and the means of bypassing stasis are determinants of the intrinsic subtypes of immortalized human mammary epithelial cells

Frontiers in Cell and Developmental Biology, 2015
Based on molecular features, breast cancers are grouped into intrinsic subtypes that have different prognoses and therapeutic response profiles. With increasing age, breast cancer incidence increases, with hormone receptor-positive and other luminal-like
Jonathan K Lee, James C Garbe, Masaru eMiyano, Martha R Stampfer, Mark A LaBarge   +4 more
doaj   +1 more source

Design Considerations for Polymer–Deep Eutectic Solvent Hybrid Systems for Transdermal Drug Delivery

Journal of Applied Polymer Science, EarlyView.
Deep eutectic solvents (DESs) act as tunable, green excipients that modulate polymer structure–property relationships to enhance drug solubility, skin permeation, stability, and controlled release. Through hydrogen‐bond interactions, DES–polymer hybrid systems enable improved transdermal performance, offering a rational, design‐driven platform for ...
Madhavi Kailas Kapale, Madhur Kulkarni, Pranav J. Shah, Furqan A. Maulvi   +3 more
wiley   +1 more source

Porous Poly(ε‐Caprolactone)/Keratin Composite Scaffolds: Structural Features, Degradation Behavior and Cell‐Material Interactions

Journal of Applied Polymer Science, EarlyView.
ABSTRACT Porous scaffolds based on pure poly(ε‐caprolactone) (PCL) and on biocomposite made of PCL and feather‐extracted β‐keratin (FK) were fabricated by salt‐leaching method. FK was incorporated into PCL to address the limited bioactivity and hydrophobic nature of PCL, with the aim of improving cell–material interactions for bone tissue engineering ...
Gianluca Rinaldi, Nancy Ferrentino, Martina Mucciolo, Valentina Sessini, Marina Paolucci, Elena Coccia, Daniela Pappalardo   +6 more
wiley   +1 more source

HERC4 downregulates KRT19 to promote lung adenocarcinoma, migration, invasion and EMT

Translational Oncology
Background: Metastasis is a major cause of treatment failure and poor prognosis in lung adenocarcinoma (LUAD). Epithelial-mesenchymal transition (EMT) plays a crucial role in promoting LUAD metastasis.
Hao-Jia Sun, Ming-Hui Peng, Zi-Yang Feng, Hua Fu, Xue-Wen Liu   +4 more
doaj   +1 more source

Bite force estimates and morphological correlations of jaw muscles in parrots

The Anatomical Record, EarlyView.
Abstract Parrots (Order: Psittaciformes) are renowned for their high bite force (BF) and morphological correlates thereof, including a highly mobile skull and two unique mandibular adductor muscles—m. pseudomasseter and m. ethmomandibularis, with the former being hypothesized to increase force output.
Ana Carolina L. Faillace, Arin Berger, Marcelo Ismar S. Santana, Adam Hartstone‐Rose   +3 more
wiley   +1 more source

Periocular keratoacanthoma: A clinicopathologic study and diagnostic challenges

The Pan-American Journal of Ophthalmology
Purpose: Keratoacanthoma (KA) is a cutaneous neoplasm that presents as a rapidly growing tumor on ultraviolet light-exposed skin. It appears as an exophytic, crater-like lesion filled with keratin. In periocular sites, the eyelids are most often affected.
Eduardo Ballalai Bordon, Emily Marcotte, Jacqueline Coblentz, Guilherme Feltrin Barros, Christian El-Hadad, Massimo Mazza, Morgan Yurchuk, Miguel Noel Burnier   +7 more
doaj   +1 more source

Keratins 17 and 19 expression as prognostic markers in oral squamous cell carcinoma

Genetics and Molecular Research, 2015
Five-year survival rates for oral squamous cell carcinoma (OSCC) are 30% and the mortality rate is 50%. Immunohistochemistry panels are used to evaluate proliferation, vascularization, apoptosis, HPV infection, and keratin expression, which are important markers of malignant progression.
Coelho, B. A., Peterle, G. T., Santos, Marcelo dos, Agostini, Lidiane Pignaton, Maia, L. L., Stur, E., Silva, C. V. M., Mendes, Suzanny Oliveira, Almança, Carlos Cesar Jorden, Freitas, Flávia Vitorino, Borçoi, Aline Ribeiro, Archanjo, Anderson Barros, Mercante, A. M. C., Nunes, Fabio Daumas, Carvalho, M. B., Silva, Eloiza Helena Tajara da, Louro, Iuri Drummond, Silva-Conforti, A. M. A   +17 more
openaire   +3 more sources

Sheep Horn Development Revealed by Multi‐Tissue and Cross‐Species Transcriptomic Analysis

Animal Research and One Health, EarlyView.
Multi‐tissue and cross‐species transcriptomics with allele‐specific expression show sheep horns are a composite organ integrating epidermal and osteogenic programs. Conserved horn gene modules and cis‐regulatory variation fine‐tune expression networks underlying horn development and size (small scurs vs. large spiral horns).
Hao Li, Yuchen He, Yangshuo Hu, Naominggaowa, Huaiqiang Yang, Zhu Meng, Fei Liu, Shiwen Zhang, Yi Jin, Mingxing Chu, Zhangyuan Pan   +10 more
wiley   +1 more source

Sequence of cDNA coding for human keratin 19 [PDF]

Nucleic Acids Research, 1987
P C, Stasiak, E B, Lane
openaire   +2 more sources

Plasma proteome reflects tissue damage and clinical manifestations in patients with inflammatory myopathies

Arthritis &Rheumatology, Accepted Article.
Objective Tissue‐specific biomarkers that are reliable and associated with clinical manifestations of idiopathic inflammatory myopathy (IIM) are lacking. The blood circulation in individuals serves as a central conduit, allowing communication between tissues and facilitating clearance and recycling of tissue‐derived proteins.
Yue‐Bei Luo, Josefin Kenrick, Angeles S Galindo‐Feria, Antonella Notarnicola, Ana Daniela Ulloa Navas, Irene Peralta‐Garcia, Orane Demuynck, Andrea Kemp, Valérie Leclair, Karin Lodin, Eveline Van Gompel, Lara Dani, Fabricio Espinosa‐Ortega, Maryam Dastmalchi, Leonid Padyukov, Charlotta Preger, María Bueno Álvez, Mathias Uhlén, Peter Nilsson, Fredrik Edfors, Lina‐Marcela Diaz‐Gallo, Elisa Pin, Ingrid E Lundberg, Begum Horuluoglu   +23 more
wiley   +1 more source