Results 211 to 220 of about 70,523,629 (289)

Engineering Stable Lentiviral Vector Producer Cells Improves LVV Production

open access: yesBiotechnology and Bioengineering, Volume 123, Issue 11, Page 3152-3164, November 2026.
ABSTRACT Stable lentiviral vector producer cell lines represent a promising platform for scalable and cost‐efficient vector manufacturing, yet their productivity is often limited by intrinsic host‐cell constraints. In this study, we aimed to identify cellular factors restricting LVV production in stable doxycycline‐inducible GPRTG producer cell lines ...
Jona Röscheise   +3 more
wiley   +1 more source

MGP_HNSC32: A H&E Morphology‐Derived 32‐Gene Prognostic Signature in Head and Neck Squamous Cell Carcinoma

open access: yesCancer Medicine, Volume 15, Issue 11, November 2026.
ABSTRACT Head and neck squamous cell carcinoma (HNSC) exhibits substantial molecular and morphological heterogeneity, yet current morphology‐based prognostic models often lack biological interpretability. We developed a transformer‐based computational framework (CTransPath) to virtually predict gene expression directly from hematoxylin and eosin (H&E ...
Di Zhao   +5 more
wiley   +1 more source

First evidence of keratinolytic activity in Simplicillium aogashimaense isolated from wool-pellet-amended soil. [PDF]

open access: yesMicrob Cell Fact
Isembart C   +7 more
europepmc   +1 more source

Sarcomatoid Intrahepatic Cholangiocarcinoma With Well‐Differentiated Squamous Cell Carcinoma Misdiagnosed as Liver Abscess: A Case Report

open access: yesCancer Reports, Volume 9, Issue 11, November 2026.
ABSTRACT Background Sarcomatoid intrahepatic cholangiocarcinoma (sICC) is a rare and highly aggressive variant of intrahepatic cholangiocarcinoma. Due to overlapping clinical and imaging features, it is frequently misdiagnosed as benign hepatic lesions, such as bacterial liver abscesses.
Jing Yang   +4 more
wiley   +1 more source

Prediction of Acute Liver Injury Trajectory in Patients Following Acetaminophen Overdose: A Multibiomarker Machine Learning Proof‐of‐Concept Study

open access: yesClinical Pharmacology &Therapeutics, Volume 120, Issue 5, Page 1326-1337, November 2026.
Clinical translation of novel therapies can be hindered by heterogeneity‐driven sample size inflation in late‐stage trials. In acetaminophen‐induced liver injury (APAP DILI), many patients recover spontaneously, diluting investigational drug efficacy signals.
Chris Humphries   +8 more
wiley   +1 more source

When intact mucosa hides a malignancy: solid-type primary intraosseous carcinoma (PIOC, NOS) of the mandible: a case report and literature review. [PDF]

open access: yesFront Dent Med
Tarakji B   +11 more
europepmc   +1 more source

Anticancer potential of berberine: Molecular pathways and current clinical trial perspectives

open access: yesJSFA reports, Volume 6, Issue 11, Page 473-489, November 2026.
Abstract Cancer is constantly rising mortality rates due to its late prognosis, poor management, and expensive treatment. Multi‐sectoral approaches for cancer management include hygienic practices, synthetic drug exploitation, radiation therapy, and diet modifications.
Muhammad Maaz   +10 more
wiley   +1 more source

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