Results 221 to 230 of about 70,523,629 (289)

Lymph Node Regression Improves Prognostic Stratification in Esophageal Squamous Cell Carcinoma Receiving Neoadjuvant Chemoimmunotherapy: A Multicenter Retrospective Cohort Study

open access: yesMedComm, Volume 7, Issue 11, November 2026.
Pathological lymph node regression grading predicts survival after neoadjuvant chemoimmunotherapy. (A) Schematic illustration of the novel five‐tier lymph node regression grading (LNRG) system and representative histopathological images. LNRG 1–4 were defined as follows: LNRG 1, no viable tumor cells observed within the tumor bed; LNRG 2, viable tumor ...
Jian Zheng   +15 more
wiley   +1 more source

Impact of Dupilumab Therapy on Skin Barrier Function in Patients With Moderate‐to‐Severe Atopic Dermatitis: A Phase IV, Non‐Randomized, Open‐Label, Parallel‐Group Clinical Study

open access: yesMedComm, Volume 7, Issue 11, November 2026.
This 16‑week study assessed impact of dupilumab on skin barrier function in patients with moderate‑to‑severe atopic dermatitis (AD). Tape‑stripped stratum corneum samples for multi‑omic profiling, alongside transepidermal water loss measurements, were collected from lesional/non‑lesional AD skin and healthy controls at seven time points.
Taoming Liu   +21 more
wiley   +1 more source

Curcumin in the Treatment of Various Diseases: Mechanism of Action, Bioavailability, Therapeutic Effects, and Current Clinical Trials

open access: yesMedComm, Volume 7, Issue 11, November 2026.
Curcumin, a naturally occurring polyphenol, exhibits significant anti‐inflammatory and antioxidant capabilities. This review elucidates the specific molecular mechanisms by which curcumin exerts therapeutic effects on various diseases, including neurological disorders, cardiovascular diseases, cancers, inflammatory disorders, and autoimmune diseases ...
Lin Wang   +15 more
wiley   +1 more source

Identification of Novel Interacting Proteins of FUZ and GPR161

open access: yesPROTEOMICS, Volume 26, Issue 11, Page 64-74, November 2026.
ABSTRACT Protein–protein interactions are central to the dynamic regulation of signaling pathways and provide critical insight into the cellular mechanisms underlying human disease. Our previous study demonstrated biochemical and genetic interactions between FUZ and GPR161 in sonic hedgehog signaling during spinal neural tube development. In this study,
Gabriella Salazar   +3 more
wiley   +1 more source

Identification of Potential Biomarkers for Ulcerative Colitis and Analysis of Immune Cell Infiltration: A Study Based on Data‐Independent Acquisition Proteomics and the GEO Public Database

open access: yesPROTEOMICS – Clinical Applications, Volume 20, Issue 6, November 2026.
ABSTRACT Background Ulcerative colitis (UC) is a challenging inflammatory bowel disease characterized by chronic inflammation of the colon's mucosal layer. Despite advances in medical research, UC lacks definitive diagnostic tests and targeted treatments.
Shuai Wang, Hualiang Deng, Dajuan Sun
wiley   +1 more source

Proteome of Human Scalp Hair Follicles. [PDF]

open access: yesCureus
Hegde A   +3 more
europepmc   +1 more source

Deep Understanding of Vaginal Microbiota in HPV‐Related Diseases From a Multi‐Omics Perspective

open access: yesVIEW Medicine, Volume 1, Issue 1, November 2026.
Current understanding of the vaginal microbiota and roles of critical vaginal bacteria, including Lactobacillus and anaerobic pathogens, in human papillomavirus (HPV) infection and HPV‐related diseases from a multi‐omics perspective. ABSTRACT There is a large number of microorganisms in the human body, which are inseparable from human health.
Jianxujie Zheng   +3 more
wiley   +1 more source

Interactive Effects of Dietary Crude Protein and Methionine Levels on Growth Performance, Carcass Quality and Blood Biochemistry of Japanese Quail During Starter and Grower Phases

open access: yesVeterinary Medicine and Science, Volume 12, Issue 6, November 2026.
Dietary crude protein and methionine interact significantly in Japanese quail. Optimal methionine ranges from 0.50%–0.70% depending on protein level and phase. Best grower performance occurs at 25% CP with 1.30% Met, yielding 161.84 g male weight gain. Females show superior breast yield (30.90%).
Elyas Piroz‐Maleki   +4 more
wiley   +1 more source

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