Results 121 to 130 of about 57,119 (251)
Current Cell/Organoid and Animal Models for Primary Sclerosing Cholangitis
Portal Hypertension &Cirrhosis, EarlyView.Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease with limited therapeutic options and a marked risk of progression to biliary fibrosis, cirrhosis, and malignancy. Progress in PSC research has been hindered by the lack of models that faithfully recapitulate the complex biliary microenvironment and disease heterogeneity ...
Qigu Yao +4 more
wiley +1 more source
Keratin 19 and mesenchymal markers for evaluation of epithelial-mesenchymal transition and stem cell niche components in primary biliary cholangitis by sequential elution-stripping multiplex immunohistochemistry. [PDF]
J Histotechnol, 2020 Paulsen JD +5 more
europepmc +1 more source
Rapid Communications in Mass Spectrometry, EarlyView.ABSTRACT Rationale Recent advances in high‐throughput molecular analyses of collagen peptides, especially ZooMS (Zooarchaeology by Mass Spectrometry), have permitted breakthroughs in the analysis of archaeological material that is highly fragmented, a factor that hinders morphological identification.
Pauline Raymond +8 more
wiley +1 more source
JCI InsightChronic lung allograft dysfunction (CLAD) is the leading cause of mortality after lung transplantation, yet its molecular mechanisms remain poorly understood.
Yuanqing Yan +10 more
doaj +1 more source
Foamed Concrete Sealing Materials for Coal Seam Gas Drainage Boreholes: A Review
Safety Science and Technology, EarlyView.This study investigates the sealing performance of foamed concrete in gas drainage boreholes. By comparing leakage pathways (a, c) with sealed systems (b, d), the research demonstrates how foamed concrete effectively fills mining‐induced fractures and resists deformation.
Jiaxing Zou +6 more
wiley +1 more source
Biomarkers to predict outcomes in diabetic foot ulcers
VIEW, EarlyView.Studies attempting to predict the healing outcome of diabetic foot ulcers (DFUs) have investigated various biological materials and recovered molecules that may aid in discriminating wounds that will heal and those that will not heal. This graphical abstract captures the commonly studied classes of biomarkers in the context of DFUs.
Julie Okiro +6 more
wiley +1 more source
A Nodule on the Cheek of a Child
JEADV Clinical Practice, EarlyView.
Monika Fida +5 more
wiley +1 more source
Peptide‐directed nanovehicles enabling tumor‐selective ROS amplification and antitumor immunity
VIEW, EarlyView.Cancer cells are vulnerable to oxidative stress, yet exploit immune tolerance to escape destruction. In contrast, their metabolic profile is markedly altered to support rapid proliferation, accompanied by elevated production of reactive oxygen species (ROS).
Manuela Calin +3 more
wiley +1 more source
Decreased Production of Tissue Plasminogen Activator in Endothelial Cells From Nasal Polyps
World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.ABSTRACT Introduction Previous studies have demonstrated that chronic rhinosinusitis with nasal polyps (CRSwNP) is characterized by excessive fibrin deposition which is related to impaired production of tissue plasminogen activator(t‐PA) by epithelial cells.
Qian‐Qian Zhang +9 more
wiley +1 more source
Integrative Zoology, EarlyView.The transition of cetaceans from a terrestrial to an aquatic environment involved a crucial sensory adaptation to environments with limited visibility. Vibrissae, important mechanoreceptors, undergo an ontogenetic transformation in odontocetes. This research describes the histomorphology of vibrissae and crypts at different developmental stages ...
Cecilia Mariana Krmpotic +10 more
wiley +1 more source