Results 101 to 110 of about 5,007,555 (282)

Expression pattern of keratin 14.

, 2015
Paraffin-embedded sections of human term placenta are stained with keratin 14 (CK14) along with Vimentin, keratin 19 (CK19), keratin 8 (CK8) and keratin 7 (CK7). Dapi is used to counterstain the nucleus. Representative images of 3 different placentas are
Wassim Abou-Kheir (201647), Assaad Eid (307257), Rebecca Assaf (802844), Rabih El-Merahbi (656498), Georges Daoud (656499)   +4 more
core   +1 more source

Keratin 19 marks poor differentiation and a more aggressive behaviour in canine and human hepatocellular tumours [PDF]

, 2010
Keratin 19 marks poor differentiation and a more aggressive behaviour in canine and human hepatocellular tumours Renee GHM van Sprundel1, Ted SGAM van den Ingh2, Valeer J Desmet3, Azeam Katoonizadeh3, Louis C Penning1, Jan Rothuizen1, Tania Roskams3 and ...
Tissue Repair, Penning, L.C., Spee, B., Bart Spee, Sprundel, R.G., van den Ingh, T.S.G.A.M., Jan Rothuizen, Valeer J Desmet, Azeam Katoonizadeh, CSCA TR1, Desmet, V.J., Geneeskunde van gezelschapsdieren, Katoonizadeh, A., Renee GHM van Sprundel, Rothuizen, J., Roskams, T., Ted SGAM van den Ingh, Tania Roskams, Louis C Penning   +18 more
core   +2 more sources

Sheep Horn Development Revealed by Multi‐Tissue and Cross‐Species Transcriptomic Analysis

Animal Research and One Health, EarlyView.
Multi‐tissue and cross‐species transcriptomics with allele‐specific expression show sheep horns are a composite organ integrating epidermal and osteogenic programs. Conserved horn gene modules and cis‐regulatory variation fine‐tune expression networks underlying horn development and size (small scurs vs. large spiral horns).
Hao Li, Yuchen He, Yangshuo Hu, Naominggaowa, Huaiqiang Yang, Zhu Meng, Fei Liu, Shiwen Zhang, Yi Jin, Mingxing Chu, Zhangyuan Pan   +10 more
wiley   +1 more source

Plasma proteome reflects tissue damage and clinical manifestations in patients with inflammatory myopathies

Arthritis &Rheumatology, Accepted Article.
Objective Tissue‐specific biomarkers that are reliable and associated with clinical manifestations of idiopathic inflammatory myopathy (IIM) are lacking. The blood circulation in individuals serves as a central conduit, allowing communication between tissues and facilitating clearance and recycling of tissue‐derived proteins.
Yue‐Bei Luo, Josefin Kenrick, Angeles S Galindo‐Feria, Antonella Notarnicola, Ana Daniela Ulloa Navas, Irene Peralta‐Garcia, Orane Demuynck, Andrea Kemp, Valérie Leclair, Karin Lodin, Eveline Van Gompel, Lara Dani, Fabricio Espinosa‐Ortega, Maryam Dastmalchi, Leonid Padyukov, Charlotta Preger, María Bueno Álvez, Mathias Uhlén, Peter Nilsson, Fredrik Edfors, Lina‐Marcela Diaz‐Gallo, Elisa Pin, Ingrid E Lundberg, Begum Horuluoglu   +23 more
wiley   +1 more source

Actomyosin forces trigger a conformational change in desmoplakin within desmosomes

Nature Communications
Desmosomes are essential cell-cell adhesion organelles that enable tension-prone tissues, like the skin and heart, to withstand mechanical stress.
Yinchen Dong, Ahmed Elgerbi, Bin Xie, Yerin Han, Adam V. Kwiatkowski, John S. Choy, Sanjeevi Sivasankar   +6 more
doaj   +1 more source

Cellular expansion of hepatocellular carcinoma organoids using decellularized liver scaffolds

Clinical Transplantation and Research
Background : A decellularized liver scaffold (DLS) is a three-dimensional acellular extracellular matrix created by removing cellular components from liver tissue. Hepatocellular carcinoma (HCC) organoids represent a useful experimental model.
Shin Hwang, I-Ji Jung, Kyoung-Jin Lee, Yun-Kyu Kim, Eunyoung Tak   +4 more
doaj   +1 more source

Age and the means of bypassing stasis are determinants of the intrinsic subtypes of immortalized human mammary epithelial cells

Frontiers in Cell and Developmental Biology, 2015
Based on molecular features, breast cancers are grouped into intrinsic subtypes that have different prognoses and therapeutic response profiles. With increasing age, breast cancer incidence increases, with hormone receptor-positive and other luminal-like
Jonathan K Lee, James C Garbe, Masaru eMiyano, Martha R Stampfer, Mark A LaBarge   +4 more
doaj   +1 more source

Keratin coated titanium as an aid to osseointegration: Physicochemical and mechanical properties

, 2023
Wool-extracted keratin has been shown to promote bone formation in vivo and may therefore be a potential novel bioactive coating material for osseous implants.
Love, Robert M, Stephen Hamlet, Ranjit, Eliza, Eliza Ranjit, Hamlet, Stephen, Robert M. Love   +5 more
core   +1 more source

Engineering Stable Lentiviral Vector Producer Cells Improves LVV Production

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Stable lentiviral vector producer cell lines represent a promising platform for scalable and cost‐efficient vector manufacturing, yet their productivity is often limited by intrinsic host‐cell constraints. In this study, we aimed to identify cellular factors restricting LVV production in stable doxycycline‐inducible GPRTG producer cell lines ...
Jona Röscheise, Lena‐Marie Eberle, Holger Laux, Kerstin Otte   +3 more
wiley   +1 more source

Transfersomes with core and surface‐loaded NF‐κB p65 siRNA for enhanced transdermal transfection and effective treatment of psoriasis

BMEMat, EarlyView.
TCPL, a transfersome with Tween 80 and PEI, enables efficient transdermal siNF‐κB delivery, resolving PEI's toxicity issue. It promotes lysosomal escape and effective transfection, silences NF‐κB, modulates immunity, and inhibits angiogenesis, alleviating psoriasis. With good biocompatibility, TCPL holds strong clinical translation potential. Schematic
Hui Xing, Yuhui Yang, Ziyi Zhao, Kai Lv, Yiran Shao, Zhi Zhang, Dong Ma   +6 more
wiley   +1 more source