Keratin 19: a key role player in the invasion of human hepatocellular carcinomas [PDF]
Objective Keratin (K)19, a biliary/hepatic progenitor cell (HPC) marker, is expressed in a subset of hepatocellular carcinomas (HCC) with poor prognosis. The underlying mechanisms driving this phenotype of K19-positive HCC remain elusive. Design
Govaere, Olivier +20 more
openaire +7 more sources
One-pot process: Microwave-assisted keratin extraction and direct electrospinning to obtain keratin-based bioplastic [PDF]
Poultry feathers are among the most abundant and polluting keratin-rich waste bio-masses. In this work, we developed a one-pot microwave-assisted process for eco-friendly keratin extraction from poultry feathers followed by a direct electrospinning (ES ...
Pelosi C. +10 more
core +1 more source
No difference in keratin thickness between inner and outer foreskins from elective male circumcisions in Rakai, Uganda. [PDF]
It has been hypothesized that increased HIV acquisition in uncircumcised men may relate to a more thinly keratinized inner foreskin. However, published data are contradictory and potentially confounded by medical indications for circumcision.
Minh H Dinh +12 more
doaj +1 more source
Functionalization Routes for Keratin from Poultry Industry Side-Streams—Towards Bio-Based Absorbent Polymers [PDF]
Keratin is a largely available protein that can be obtained from the ca. 3 million tons of feathers that the European poultry industry produces as a side-stream.
Pérez-Puyana, Víctor Manuel +24 more
core +1 more source
Keratin 19 Epithelial Patterns in Cirrhotic Stroma Parallel Hepatocarcinogenesis [PDF]
Cirrhotic septa harbor vessels and inflammatory, fibrogenic, and ductular epithelial cells, collectively referred to as the ductular reaction (DR). Lack of the DR in the stromal compartment around hepatocellular carcinoma (HCC) has been documented; however, the relationship of epithelial keratin 19 (K19) structures to progression of intralesional ...
Jochen K M, Lennerz +2 more
openaire +2 more sources
An Integrative Bioinformatic Analysis for Keratinase Detection in Marine-Derived Streptomyces
Keratinases present promising biotechnological applications, due to their ability to degrade keratin. Streptomyces appears as one of the main sources of these enzymes, but complete genome sequences of keratinolytic bacteria are still limited.
Ricardo Valencia +5 more
doaj +1 more source
Keratin 13 is a more specific marker of conjunctival epithelium than keratin 19.
To evaluate the expression patterns of cytokeratin (K) 12, 13, and 19 in normal epithelium of the human ocular surface to determine whether K13 could be used as a marker for conjunctival epithelium.Total RNA was isolated from the human conjunctiva and central cornea.
Ramirez-Miranda, Arturo +4 more
openaire +3 more sources
A Ca2+-Mediated Switch of Epiplakin from a Diffuse to Keratin-Bound State Affects Keratin Dynamics
Keratins exert important structural but also cytoprotective functions. They have to be adaptable to support cellular homeostasis. Epiplakin (EPPK1) has been shown to decorate keratin filaments in epithelial cells and to play a protective role under ...
Rudolf E. Leube +9 more
core +1 more source
Epitope Mapping of Monoclonal Antibodies to Keratin 19 Using Keratin Fragments, Synthetic Peptides and Phage Peptide Libraries [PDF]
To generate tools for monitoring processing and folding in keratin intermediate filaments, a group of monoclonal antibodies reacting with the intermediate filament protein keratin 19 were studied using different approaches to define the structure and localization of their epitopes. The binding pattern to bacterially expressed human keratin 19 fragments
V, Böttger +4 more
openaire +2 more sources
Blackcurrant Extract with Phytoestrogen Activity Alleviates Hair Loss in Ovariectomized Rats
Ancocyanin-rich blackcurrant extract (BCE) has phytoestrogen activity; however, its effect on hair follicles is unknown. Additionally, hair loss is known to occur during menopause in women owing to decreased estrogen secretion.
Naoki Nanashima, Kayo Horie
doaj +1 more source

