Results 41 to 50 of about 56,636 (187)

Heterogeneity of estrogen receptor expression in circulating tumor cells from metastatic breast cancer patients. [PDF]

PLoS ONE, 2013
BACKGROUND: Endocrine treatment is the most preferable systemic treatment in metastatic breast cancer patients that have had an estrogen receptor (ER) positive primary tumor or metastatic lesions, however, approximately 20% of these patients do not ...
Anna Babayan, Juliane Hannemann, Julia Spötter, Volkmar Müller, Klaus Pantel, Simon A Joosse   +5 more
doaj   +1 more source

Two mechanisms regulate keratin K15 expression in keratinocytes:role of PKC/AP-1 and FOXM1 mediated signalling

, 2012
Background: Keratin 15 (K15) is a type I keratin that is used as a marker of stem cells. Its expression is restricted to the basal layer of stratified epithelia, and the bulge in hair follicles.
Ahmad Waseem (155362), Amrita Bose, Ahmad Waseem, Leigh, IM, Waseem, Ahmad, Leigh, Irene M., Hutchison, Iain L., Iain L. Hutchison (155346), Hong Wan, Leigh Irene M., Hutchison, IL, Teh, MT, Iain L Hutchison, Muy-Teck Teh, Wan Hong, Teh, M-T, Wan, Hong, Bose, A, Irene M. Leigh (155355), Teh Muy-Teck, Muy-Teck Teh (155335), Amrita Bose (155329), Bose, Amrita, Wan, H, Waseem Ahmad, Irene M Leigh, Waseem, A, Hong Wan (149928), Hutchison Iain L., Teh, Muy-Teck, Bose Amrita   +30 more
core   +1 more source

The Developmental & Molecular Requirements for Ensuring that Human Pluripotent Stem Cell-Derived Hair Follicle Bulge Stem Cells Have Acquired Competence for Hair Follicle Generation Following Transplantation

Cell Transplantation, 2021
When using human induced pluripotent stem cells (hiPSCs) to achieve hair follicle (HF) replacement, we found it best to emulate the earliest fundamental developmental processes of gastrulation, ectodermal lineage commitment, and dermogenesis.
Michel R. Ibrahim, Walid Medhat, Hasan El-Fakahany, Hamza Abdel-Raouf, Evan Y. Snyder   +4 more
doaj   +1 more source

Cross-talk between microRNA-let7c and transforming growth factor-β2 during epithelial-to-mesenchymal transition of retinal pigment epithelial cells [PDF]

International Journal of Ophthalmology, 2020
AIM: To explore the roles of microRNA-let7c (miR-let7c) and transforming growth factor-β2 (TGF-β2) and cellular signaling during epithelial-to-mesenchymal transition (EMT) of retinal pigment epithelial cells. METHODS: Retinal pigment epithelial (ARPE-19)
Qu-Zhen Deji, Feng Yan, Wang-Dui Zhaba, Ya-Jun Liu, Jie Yin, Zhen-Ping Huang   +5 more
doaj   +1 more source

MCF-7 Human Breast Cancer Cells Form Differentiated Microtissues in Scaffold-Free Hydrogels.

PLoS ONE, 2015
Three-dimensional (3D) cultures are increasing in use because of their ability to represent in vivo human physiology when compared to monolayer two-dimensional (2D) cultures.
Marguerite M Vantangoli, Samantha J Madnick, Susan M Huse, Paula Weston, Kim Boekelheide   +4 more
doaj   +1 more source

Immune Cells Profiles in the Different Sites of COVID-19-Affected Lung Lobes in a Single Patient

Frontiers in Medicine, 2022
Whereas the COVID-19 disease pathophysiology is under investigation, it is important to identify the pathways of viral transmission and inflammation from the pre-illness to the disease-onset stages.
Sadahiro Iwabuchi, Kyohei Miyamoto, Mayuko Hatai, Yurina Mikasa, Masahiro Katsuda, Shin-ichi Murata, Toshikazu Kondo, Hiroki Yamaue, Shinichi Hashimoto   +8 more
doaj   +1 more source

Keratin 18 is associated with a subset of older taste cells in the rat [PDF]

, 1995
All or nearly all intragemmal (elongated) cells of rat taste buds were immunopositive for keratins 7, 8, and 19. In contrast, keratin 18 was detected in 19±5 cells per taste bud (mean±sd), or about 25% of the intragemmal cells.
Zhang, Chunxiao, Zeng, Qun, Wong, Lianna, Cotter, Murray, Oakley, Bruce, Lawton, Anne   +5 more
core   +1 more source

Lung Cancer-Associated Keratin 19 Fragments: Development and Biochemical Characterisation of the New Serum Assay Enzymun-Test Cyfra 21–1

The International Journal of Biological Markers, 1994
From a panel of 4 murine monoclonal antibodies directed against keratin 19 various antibody combinations were evaluated in solid-phase enzyme-linked sandwich immunoassays for detection of soluble keratin 19 fragments in patient sera.
H. Bodenmüller, B. Ofenloch-Hähnle, E.B. Lane, A. Dessauer, V. Böttger, F. Donié   +5 more
doaj   +1 more source

Detection of lymph node metastasis in lung cancer patients using a one-step nucleic acid amplification assay: a single-centre prospective study

Journal of Translational Medicine, 2019
Background The use of one-step nucleic acid amplification (OSNA) allows for lymph node (LN) metastasis to be detected rapidly and accurately. We conducted a prospective single-centre clinical trial to evaluate OSNA assay in detecting LN metastasis of ...
María Escalante Pérez, María Teresa Hermida Romero, Begoña Otero Alén, Mónica Álvarez Martínez, Ricardo Fernández Prado, Mercedes de la Torre Bravos, Ángel Concha López   +6 more
doaj   +1 more source

Identification of a population of epidermal squamous cell carcinoma cells with enhanced potential for tumor formation. [PDF]

PLoS ONE, 2013
Epidermal squamous cell carcinoma is among the most common cancers in humans. These tumors are comprised of phenotypically diverse populations of cells that display varying potential for proliferation and differentiation. An important goal is identifying
Gautam Adhikary, Dan Grun, Candace Kerr, Sivaprakasam Balasubramanian, Ellen A Rorke, Mohan Vemuri, Shayne Boucher, Jackie R Bickenbach, Thomas Hornyak, Wen Xu, Matthew L Fisher, Richard L Eckert   +11 more
doaj   +1 more source