Results 101 to 110 of about 55,821 (251)

The Tissue-dependent Keratin 19 Gene Transcription Is Regulated by GKLF/KLF4 and Sp1

Journal of Biological Chemistry, 2000
Keratins play critical roles in cellular differentiation and cytoskeletal organization. Keratin 19 (K19) is unique because it has been implicated as a marker of stem cells in some tissues, such as the hair follicle in the skin. It is also associated with malignant transformation in esophageal and pancreatic cancers.
F H, Brembeck, A K, Rustgi
openaire   +2 more sources

Anticancer potential of berberine: Molecular pathways and current clinical trial perspectives

JSFA reports, EarlyView.
Abstract Cancer is constantly rising mortality rates due to its late prognosis, poor management, and expensive treatment. Multi‐sectoral approaches for cancer management include hygienic practices, synthetic drug exploitation, radiation therapy, and diet modifications.
Muhammad Maaz, Muhammad Tauseef Sultan, Muhammad Israr, Waqas Ahmad Khan, Fahad Tanveer, Muzzamal Hussain, Muhammad Imran, Ahmed Mujtaba, Anjuman Gul Memon, Muhammad Atif, Entessar Al Jbawi   +10 more
wiley   +1 more source

Keratin 19 interacts with GSK3β to regulate its nuclear accumulation and degradation of cyclin D3. [PDF]

Mol Biol Cell, 2021
Sharma P, Tiufekchiev S, Lising V, Chung SW, Suk JS, Chung BM.   +5 more
europepmc   +1 more source

Keratins 17 and 19 expression as prognostic markers in oral squamous cell carcinoma

Genetics and Molecular Research, 2015
Five-year survival rates for oral squamous cell carcinoma (OSCC) are 30% and the mortality rate is 50%. Immunohistochemistry panels are used to evaluate proliferation, vascularization, apoptosis, HPV infection, and keratin expression, which are important markers of malignant progression.
Coelho, B. A., Peterle, G. T., Santos, Marcelo dos, Agostini, Lidiane Pignaton, Maia, L. L., Stur, E., Silva, C. V. M., Mendes, Suzanny Oliveira, Almança, Carlos Cesar Jorden, Freitas, Flávia Vitorino, Borçoi, Aline Ribeiro, Archanjo, Anderson Barros, Mercante, A. M. C., Nunes, Fabio Daumas, Carvalho, M. B., Silva, Eloiza Helena Tajara da, Louro, Iuri Drummond, Silva-Conforti, A. M. A   +17 more
openaire   +3 more sources

Bromelain as the enzyme of the future: A global bibliometric mapping of its applications and emerging trends

Journal of the Science of Food and Agriculture, EarlyView.
Abstract INTRODUCTION Bromelain, a complex mixture of proteolytic enzymes primarily extracted from plants of the Bromeliaceae family, has gained prominence because of its broad industrial applicability, particularly in the food, pharmaceutical and cosmetic sectors.
Genésio José da Silva Neto, Tonny Cley Campos Leite, Mônica Tejo Cavalcanti, Geany Targino Sousa Pedrosa, Rerisson do Nascimento Alves, Amanda Reges de Sena, Mônica Correia Gonçalves   +6 more
wiley   +1 more source

High‐ and Ultra‐High‐Frequency Ultrasound Identifies a Subclinical Link Between Suppurative Comedonal Nevus and Hidradenitis Suppurativa

Journal of Ultrasound in Medicine, EarlyView.
Suppurative nevus comedonicus (SNC) is a variant of nevus comedonicus in which the characteristic features coexist with recurrent inflammatory lesions that clinically resemble those of hidradenitis suppurativa (HS). We present the ultrasound characteristics of this entity and emphasize the value of high‐resolution dermatologic ultrasound both as a ...
Marta Ivars, Katia Henostroza, Fabià Torres‐Betato, Eva Vilarrasa, Ximena Wortsman   +4 more
wiley   +1 more source

Chromosomal Localization of Candidate Genes for Fiber Growth and Color in Alpaca (Vicugna pacos)

Frontiers in Genetics, 2019
The alpaca (Vicugna pacos) is an economically important and cultural signature species in Peru. Thus, molecular genomic information about the genes underlying the traits of interest, such as fiber properties and color, is critical for improved breeding ...
Mayra N. Mendoza, Terje Raudsepp, Fahad Alshanbari, Gustavo Gutiérrez, F. Abel Ponce de León   +4 more
doaj   +1 more source

Validation of the Investigator's Global Assessment Scale for Epidermolysis Bullosa Simplex

JEADV Clinical Practice, EarlyView.
ABSTRACT Background There is a lack validated outcome measures to assess wound severity in epidermolysis bullosa simplex (EBS). Objectives To assess the reliability and validity of the Investigator's Global Assessment (IGA) scale and a newly developed palms/soles subscale through in‐clinic scoring and review of patient‐submitted photographs.
Pirunthan Pathmarajah, Shufeng Li, Maya B. Mathur, Joyce M. C. Teng, M. Peter Marinkovich, Austin N. Johnson, Shehla Admani, Edward Eid, Joanna Tu, Dominique C. Mitchell, Lila Perrone, Ricardo Villanueva Gaona, Jean Y. Tang, Albert S. Chiou   +13 more
wiley   +1 more source

Prognostic significance of inflammation-based prognostic scoring in patients with upper urinary tract urothelial carcinoma

International Brazilian Journal of Urology
Objectives: To investigate whether Glasgow Prognostic Score has prognostic significance in patients with upper urinary urothelial carcinoma. Patients and methods: We retrospectively reviewed the clinical records of 74 patients with upper urinary ...
Taisuke Suyama, Shigeki Kanbe, Masanobu Maegawa, Hirofumi Shimizu, Koichi Nakajima   +4 more
doaj   +1 more source

Nail Toxicities Associated With Anticancer Therapies in Children

JEADV Clinical Practice, EarlyView.
ABSTRACT Nail toxicities are a frequent yet often underrecognized component of dermatologic adverse events in children receiving anticancer therapies. Both conventional cytotoxic chemotherapy and newer targeted agents can affect the nail matrix, nail bed and periungual tissues, producing a broad spectrum of clinical manifestations that range from ...
Luca Rapparini, Michela Starace
wiley   +1 more source