Results 131 to 140 of about 137,265 (305)

Keratinocyte-specific ablation of Mcpip1 impairs skin integrity and promotes local and systemic inflammation

, 2019
MCPIP1 (Regnase-1, encoded by the ZC3H12A gene) regulates the mRNA stability of several inflammatory cytokines. Due to the critical role of this RNA endonuclease in the suppression of inflammation, Mcpip1 deficiency in mice leads to the development of ...
Santamaria-Babi, Luis F., Mikula, Michal, Szukała, Weronika, Rumienczyk, Izabela, Kwiecinska, Patrycja, Devos, Michael, Jura, Jolanta, Lichawska-Cieslar, Agata, Borowczyk, Julia, Declercq, Wim, Borowczyk-Michałowska, Julia, Konieczny, Piotr, Cichy, Joanna, Szukala, Weronika, Santamaria-Babi, Luis F, Pietrzycka, Roza, Fu, Mingui, Paziewska, Agnieszka, Kulecka, Maria   +18 more
core   +1 more source

Localized Hydrogen Release Driven by Mg–Pd Microgalvanic Cells from 3D‐Printed Microneedles Reverses Redox Homeostasis for Psoriasis Treatment

Advanced Science, EarlyView.
A 3D printing microneedle (MP‐MN), loading magnesium‐based micro‐galvanic cells (MP), is designed for improving psoriasis. H2 generated from MP‐MN scavenges ROS and •OH, actives NRF2‐KEAP1 pathway, and decreases inflammation, thereby effectively restoring the oxidative stress homeostasis of psoriatic skin and suppressing the excessive proliferation of ...
Xinyue Shao, Zongyan He, Ning Yang, Lixuan Yin, Xujie Sun, Jingtong Qi, Xiaolong Feng, Yihui Zhang, Yiran Liu, Zhengwei Huang, Tianqun Lang   +10 more
wiley   +1 more source

EC_1.5 and CV₇₀ in the keratinocyte activation assay.

EC1.5 and CV70 in the keratinocyte activation assay.
Yoshio Tsujino (1283079), Mayuko Koreishi (101892), Ayano Satoh (101896), Haruna Sato (6932987), Kosuke Kato (6507053), Yoshimasa Nakamura (2429446)   +5 more
core   +1 more source

Composition‐Aware Cross‐Sectional Integration for Spatial Transcriptomics

Advanced Intelligent Discovery, EarlyView.
Multi‐section spatial transcriptomics demands coherent cell‐type deconvolution, domain detection, and batch correction, yet existing pipelines treat these tasks separately. FUSION unifies them within a composition‐aware latent framework, modeling reads as cell‐type–specific topics and clustering in embedding space.
Qishi Dong, Zijian Huang, Xuanwu Wang, Zhenghui Feng, Wei Liu, Bingding Huang   +5 more
wiley   +1 more source

Autonomous AI‐Driven Design for Skin Product Formulations

Advanced Intelligent Discovery, EarlyView.
This review presents a comprehensive closed‐loop framework for autonomous skin product formulation design. By integrating artificial intelligence‐driven experiment selection with automated multi‐tiered assays, the approach shifts development from trial‐and‐error to intelligent optimisation.
Yu Zhang, Yongrui Xiao, Chunlin Chen, Dimitrios Tsaoulidis, Kai Yang, Tao Chen   +5 more
wiley   +1 more source

Autologous non-cultured melanocyte–keratinocyte transplantation in the treatment of vitiligo: patient selection and perspectives

, 2018
Dalia Bassiouny, Samia Esmat Department of Dermatology, Kasr El-Ainy Teaching Hospital, Faculty of Medicine, Cairo University, Cairo, Egypt Abstract: Autologous non-cultured melanocyte–keratinocyte transplantation procedure (MKTP) is one of the ...
Bassiouny D, Esmat S
core  

Keratinocyte survival, differentiation, and death: many roads lead to mitogen-activated protein kinase

, 2003
The epidermis is a dynamic and continually renewing surface that provides and maintains a life-sustaining interface with the environment. The epidermal keratinocyte, the major cell type of the epidermis, undergoes a complex and carefully choreographed ...
Eckert, Richard L, Bone, Frederic, Efimova, Tatiana, Balasubramanian, Sivaprakasam, Sturniolo, Michael, Crish, James F, Deucher, Anne, Dashti, Shervin R   +7 more
core   +1 more source

Engineering Intelligent iPSC Biomanufacturing: Integrating Robotic Automation, AI, and Process Control

Advanced Intelligent Systems, EarlyView.
This review highlights recent advances in automated iPSC culture systems integrating robotics, advanced imaging, artificial intelligence, and process control. These technologies improve reproducibility, scalability, and quality in cell expansion, differentiation, and real‐time monitoring, while emerging AI‐enabled and closed‐loop approaches offer new ...
Hyoryong Lee, Roma Desai, Byunggik Kim, Deok‐Ho Kim   +3 more
wiley   +1 more source

Noninvasive Electromagnetic Fields on Keratinocyte Growth and Migration

, 2010
Although evidence has shown that very small electrical currents produce a beneficial therapeutic result for wounds, noninvasive electromagnetic field (EMF) therapy has consisted mostly of anecdotal clinical reports, with very few well-controlled ...
Ma, Qianli, Davis, Stephen C, Huo, Ran, Wu, James J, Chin-Nuke, Kayla, Li, Jie, Miyar, Maria E, Chen, Juan, Jing, Yuqi   +8 more
core   +1 more source

Morphological description of the oropharyngeal cavity of Kinosternon scorpioides scorpioides (Linnaeus, 1766), (Testudines: Kinosternidae)

The Anatomical Record, EarlyView.
Gross morphology, Light Microscopy and Scanning Electron Microscopy revealed the structural organization of the oropharyngeal cavity of Kinosternon scorpioides scorpioides, characterized by mucous epithelium, epithelial pores, and developed lingual papillae.
Andréa Magalhães Bezerra, Diego Ferreira de Sousa, Luane Botelho, André Luís Nogueira Lima, Érika Branco, Elane Guerreiro Giese, Washington Luís Pereira, Ana Rita de Lima   +7 more
wiley   +1 more source