Results 241 to 250 of about 322,086 (387)

Recent advances in animal models for pathological scar research: A comprehensive review of experimental approaches and translational relevance

Animal Models and Experimental Medicine, EarlyView.
Animal models remain indispensable in the study of pathological scars, each offering unique advantages and constraints. Their integration with in vitro and ex vivo systems is key to developing personalized, clinically translatable antifibrotic therapies. Abstract Pathological scarring, manifested in the form of hypertrophic scars (HTS) and keloid scars
Diana‐Larisa Ancuța, Mariana Văduva, Cristin Coman, Iuliana Caraș   +3 more
wiley   +1 more source

Keratinocytes as active regulators of cutaneous and mucosal immunity: a systematic review across inflammatory epithelial disorders. [PDF]

Front Immunol
Klimitz FJ, Shen Y, Repetto F, Brown S, Knoedler L, Ko CJ, Abu Hussein N, Crisler WJ, Adams T, Kaminski N, Lian CG, Murphy GF, Hsia HC, Pomahac B, Kauke-Navarro M.   +14 more
europepmc   +1 more source

A synthetic sandalwood odorant induces wound-healing processes in human keratinocytes via the olfactory receptor OR2AT4.

Journal of Investigative Dermatology, 2014
D. Busse, Philipp Kudella, Nana-Maria Grüning, G. Gisselmann, S. Ständer, T. Luger, F. Jacobsen, L. Steinsträsser, R. Paus, P. Gkogkolou, M. Böhm, H. Hatt, H. Benecke   +12 more
semanticscholar   +1 more source

Advances and Challenges in Micro/Nanocarrier‐Based Dermal Drug Delivery Systems for Acne Treatment

Advanced NanoBiomed Research, EarlyView.
Topical acne treatment faces challenges from skin barriers and complex causes. Micro/nanocarriers improve drug delivery by enhancing bioavailability, targeting, and duration. Combining carriers creates synergistic effects for systematic intervention.
Jintao Yang, Jie Chen, Yunmiao Ma, Qingwei Zhou, Yu Kong, Yingxiang Chen, Junjie Chi, Haihua Hu   +7 more
wiley   +1 more source

Response of Oral and Skin Keratinocytes to Oxidative Stress. [PDF]

Cells
Zhang Y, Han C, Yuan H, DiPietro LA, Chen L.   +4 more
europepmc   +1 more source

Histamine-Evoked Signaling in Human Primary Keratinocytes [PDF]

, 2012
Lydia Thé, Sarah R. Wilson, Diana M. Bautista   +2 more
openalex   +1 more source

Decoding the Pathophysiology of Autoimmune Diseases—Mechanism, Triggers, and Nanotherapeutics: A Review

Advanced NanoBiomed Research, EarlyView.
This review highlights how autoimmune diseases arise from intertwined immunological, genetic, and environmental factors, emphasizing gut microbiota dysbiosis as a pivotal driver. It outlines emerging nanotechnology‐based strategies—such as liposomes, hydrogels, and polymeric nanoparticles—that enhance targeted drug delivery, minimize systemic toxicity,
Md. Meraj Ansari, Yunhui Min, Eun‐Ju Ko, Doyoung Kwon, Rehan Khan, Young‐Ok Son   +5 more
wiley   +1 more source

Unmasking Hidden Clues in Cutaneous Viral Infections: Histopathological Insights Into Keratinocytic Features of Herpes Simplex Virus, Varicella Zoster Virus, and Molluscum Contagiosum. [PDF]

Cureus
Platero Portillo T, Dhaliwal D, Mehravaran S, Ketcham M, Wu J, Ramani N, Diwan AH.   +6 more
europepmc   +1 more source

Loss of keratinocyte Mcpip1 abruptly activates the IL-23/Th17 and Stat3 pathways in skin inflammation

, 2020
Agata Lichawska-Cieślar, Piotr Konieczny, Weronika Szukała, Wim Declercq, Mingui Fu, Jolanta Jura   +5 more
openalex   +1 more source

Linezolid prevents fibroblast activation and ameliorates tissue fibrosis by inhibition of mitochondrial translation

Arthritis &Rheumatology, Accepted Article.
Background Beyond its role as a ribosome‐targeting antibiotic, linezolid was recently shown to modulate immune responses by inhibiting mitochondrial translation. Since mitochondrial dysfunction is implicated in various fibrotic diseases, including systemic sclerosis (SSc), this study aimed to evaluate the antifibrotic potential of linezolid and ...
Xuezhi Hong, Yanhua Xiao, Haodong Qi, Shihao Zhu, Tim Filla, Andrea‐Hermina Györfi, Yi‐Nan Li, Meilin Xu, Langxian Zhi, Thuong Trinh‐Minh, Clara Dees, Georg Schett, Jörg H.W. Distler, Alexandru‐Emil Matei   +13 more
wiley   +1 more source