Results 71 to 80 of about 19,974 (294)

An Unbiased Geometry‐Resolved Membrane Platform for Proteome‐Scale Discovery of Membrane Curvature Sensors

open access: yesAdvanced Science, EarlyView.
A novel geometry‐resolved membrane platform provides a seamlessly integrated pipeline for studying curvature‐sensing proteins. By linking shotgun proteomics with quantitative imaging, this approach enables both the unbiased discovery and rigorous validation of novel sensors across the entire curvature range—positive, negative, and zero.
Takumi Komikawa   +6 more
wiley   +1 more source

TNFRSF21 Orchestrates Epithelial Keratinization and Tight Junction Integrity in Periodontitis-Associated Oral Mucosal Repair

open access: yesFrontiers in Bioscience-Landmark
Background: The progression of periodontitis is accompanied by destruction of keratinized epithelium, while members of the tumor necrosis factor receptor superfamily (TNFRSF) play critical roles in epithelial repair.
Wenhao Zhang   +10 more
doaj   +1 more source

Epithelial Keratins Modulate cMet Expression and Signaling and Promote InlB-Mediated Listeria monocytogenes Infection of HeLa Cells

open access: yesFrontiers in Cellular and Infection Microbiology, 2018
The host cytoskeleton is a major target for bacterial pathogens during infection. In particular, pathogens usurp the actin cytoskeleton function to strongly adhere to the host cell surface, to induce plasma membrane remodeling allowing invasion and to ...
Rui Cruz   +13 more
doaj   +1 more source

Temporal Trajectories of the Tau Aggregate Interactome Reveal Stage‐Specific Vulnerabilities in Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
Tau populations with different aggregation states associate with distinct sets of proteins in the Alzheimer's disease brain. Proteomic discovery combined with single‐molecule analysis in neurons reveals dynamic associations involving proteostasis, metabolism and RNA biology.
Dorothea Böken   +8 more
wiley   +1 more source

Die nächsten Homologen des «Sarkosins» und des «Keratins»

open access: yes, 1909
DIE NÄCHSTEN HOMOLOGEN DES «SARKOSINS» UND DES «KERATINS» Details: Zeitschrift für physiologische Chemie: 1.1877-20.1895 Hoppe-Seyler's Zeitschrift für physiologische Chemie: 21.1895- 112.1921 (-) Hoppe-Seyler's Zeitschrift für Physiologische ...
Gansser, Emil
core   +3 more sources

Keratin 6, 16 and 17—Critical Barrier Alarmin Molecules in Skin Wounds and Psoriasis

open access: yesCells, 2019
Located at the skin surface, keratinocytes (KCs) are constantly exposed to external stimuli and are the first responders to invading pathogens and injury.
Xiaowei Zhang   +2 more
doaj   +1 more source

THE STRUCTURE OF ALPHA KERATIN [PDF]

open access: yesProceedings of the National Academy of Sciences, 1957
Known structural principles (close packing, maximum hydrogen bonding, the tendency of like groups to be surrounded in like manner, and the approximate constancy of interatomic distances and bond angles) are used, with meridional and equatorial x-ray data, to deduce and check the structure pattern for alpha-keratin.
openaire   +3 more sources

Expression and purification of soluble G. gallus β-keratins.

open access: yes, 2017
(A) Construction of expression vectors for recombinant Chr2_FK4, Chr25_FK25, and Chr27_FK12 β-keratins. (B) SDS-PAGE analysis of recombinant keratins expressed in E. coli, and purification of soluble Chr2_FK4 and Chr27_FK12 β-keratins.
Seon Yeong Park (3775489)   +6 more
core   +1 more source

Synthese und aktivitätsbasierte Proteinprofilierung identifizieren die Aldo‐Keto‐Reduktase 1C3 als Zielprotein der Myxoglucamide

open access: yesAngewandte Chemie, EarlyView.
Myxoglucamid A – ein neuartiges, aus Myxobakterien isoliertes Glykolipopeptid – wurde erstmals totalsynthetisch hergestellt. Mittels aktivitätsbasierter Proteinprofilierung (ABPP) wurde die Aldo‐Keto‐Reduktase 1C3 (AKR1C3) als primäres Zielprotein in menschlichen Zellen identifiziert.
Thomas Siemon   +9 more
wiley   +1 more source

Hydrolyse des Keratins aus Horn und aus Wolle

open access: yes, 1907
HYDROLYSE DES KERATINS AUS HORN UND AUS WOLLE Details: Zeitschrift für physiologische Chemie: 1.1877-20.1895 Hoppe-Seyler's Zeitschrift für physiologische Chemie: 21.1895- 112.1921 (-) Hoppe-Seyler's Zeitschrift für Physiologische Chemie (52 ...
Abderhalden, Emil Arthur Voitinovici
core   +3 more sources

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