Results 81 to 90 of about 19,974 (294)

Keratins Stabilize Hemidesmosomes through Regulation of β4-Integrin Turnover [PDF]

, 2015
Epidermal integrity and wound healing depend on remodeling of cell-matrix contacts including hemidesmosomes. Mutations in β4-integrin and plectin lead to severe epidermolysis bullosa (EB).
Eriksson, John E., Seltmann, Kristin, Wiche, Gerhard, Cheng, Fang, Magin, Thomas M.   +4 more
core   +1 more source

Synthesis and Activity‐Based Protein Profiling Identifies Aldo‐Keto Reductase 1C3 as Target Protein of Myxoglucamides

Angewandte Chemie International Edition, EarlyView.
Myxoglucamide A—a novel glycolipopeptide isolated from myxobacteria—was synthesized, and activity‐based protein profiling identified aldo‐keto reductase 1C3 (AKR1C3) as its main target in human cells. Structure‐activity relationship studies, together with biophysical characterization and X‐ray crystallography, elucidated the structural basis of AKR1C3 ...
Thomas Siemon, Vivek K. Mishra, Mingming Zhao, Konrad Büssow, Alexander Popoff, Chengzhang Fu, Rolf Müller, Lothar Jänsch, Wulf Blankenfeldt, Mark Brönstrup   +9 more
wiley   +1 more source

Orofacial Epidermoid Cysts: A Case Series

Clinical Case Reports
Epidermoid cysts can occur anywhere in the body but are uncommon in the orofacial region, with a 7% incidence in the head and neck and 1.6% in the oral cavity.
Manoj Adhikari, Kanistika Jha, Puja Thapa, Sarita K.C., Padam Raj Neupane, Pratibha Poudel   +5 more
doaj   +1 more source

Differentiation-Dependent Expression of Keratins in Human Oral Epithelia [PDF]

, 1986
The polypeptide composition of epithelial keratins varies with the state of differentiation. The epithelia lining the human oral cavity show regional variations in their histology.
Vedtofte, Poul, Dabelsteen, Erik, Clausen, Henrik, Moe, Dennis, Sun, Tung-Tien, Dale, Beverly   +5 more
core   +1 more source

Bite force estimates and morphological correlations of jaw muscles in parrots

The Anatomical Record, EarlyView.
Abstract Parrots (Order: Psittaciformes) are renowned for their high bite force (BF) and morphological correlates thereof, including a highly mobile skull and two unique mandibular adductor muscles—m. pseudomasseter and m. ethmomandibularis, with the former being hypothesized to increase force output.
Ana Carolina L. Faillace, Arin Berger, Marcelo Ismar S. Santana, Adam Hartstone‐Rose   +3 more
wiley   +1 more source

Evolution and Complexity of the Genes Encoding the Keratins of Human Epidermal Cells [PDF]

, 1983
The keratins are a family of proteins (Mr = 40–70 K) that form 8-nm intermediate filaments in the cytoplasm of most vertebrate epithelial cells. Each epithelial cell expresses its own subset of keratins, which consists of about 2 to 5 polypeptides.
Fuchs, Elaine
core   +1 more source

Sheep Horn Development Revealed by Multi‐Tissue and Cross‐Species Transcriptomic Analysis

Animal Research and One Health, EarlyView.
Multi‐tissue and cross‐species transcriptomics with allele‐specific expression show sheep horns are a composite organ integrating epidermal and osteogenic programs. Conserved horn gene modules and cis‐regulatory variation fine‐tune expression networks underlying horn development and size (small scurs vs. large spiral horns).
Hao Li, Yuchen He, Yangshuo Hu, Naominggaowa, Huaiqiang Yang, Zhu Meng, Fei Liu, Shiwen Zhang, Yi Jin, Mingxing Chu, Zhangyuan Pan   +10 more
wiley   +1 more source

Update on hair fiber assessment [PDF]

Surgical & Cosmetic Dermatology
Damage caused by chemical, physical, and thermal procedures can disrupt the natural morphological characteristics of the hair, causing the strands to become dry, dull, weak, and brittle.
Tércio Elyan Azevedo Martins, Andressa Costa de Oliveira, Beatriz Regazzi de Gusmão, Alexandre de Almeida Filippo, Fabiane Mulinari-Brenne   +4 more
doaj   +1 more source

Establishment of Humanized EFNB2/B3 Murine Models for Investigating Nipah Virus Pathogenesis

Animal Research and One Health, EarlyView.
ABSTRACT Nipah virus (NiV) is a zoonotic paramyxovirus classified as a WHO priority pathogen, which causes severe respiratory disease and encephalitis in humans with high mortality. Currently, no licensed vaccines or specific antiviral therapies are available.
Wei Dong, Ning Liu, Weining Kong, Xiang Gao, Feifei Guan, Shan Gao, Yuanwu Ma   +6 more
wiley   +1 more source

Immunohistochemical demonstration of keratins in the epidermal layers of the Malayan pangolin (Manis javanica), with remarks on the evolution of the integumental scale armour

European Journal of Histochemistry, 2013
Using immunohistochemistry, the study demonstrates the distribution of keratins (pan-keratin with CK1-8, 10, 14-16, 19; keratins CK1, 5, 6, 9, 10; hair keratins AE13, AE14) in the epidermis of the Malayan pangolin (Manis javanica).
W. Meyer, M. Liumsiricharoen, A. Suprasert, L.G. Fleischer, M. Hewicker-Trautwein   +4 more
doaj   +1 more source