Results 61 to 70 of about 19,974 (294)

Keratins in health and disease

open access: yes, 2015
The cytoprotective keratins (K) compose the intermediate filaments of epithelial cells and their inherited and spontaneous mutations give rise to keratinopathies.
Alam, Catharina   +4 more
core   +1 more source

An Innervated Human Skin Equivalent that Electrically Encodes Mechanical and Thermal Stimuli

open access: yesAdvanced Science, EarlyView.
An innervated human skin equivalent is integrated with high‐density microelectrode arrays to reveal how engineered free nerve ending–like structures translate touch and temperature into electrical codes. Mechanical indentation and thermal stimulation engage the engineered somatosensory circuitry and evoke distinct firing and waveform signatures ...
Daniele Bellantoni   +6 more
wiley   +1 more source

Keratinases: emerging trends in production and applications as novel multifunctional biocatalysts

open access: yesKuwait Journal of Science, 2016
Keratinases are proteolytic enzymes capable of degrading rigid and insoluble keratinous proteins present in skinand appendages. They are produced in the keratinous substrates such as feather, hair, wool, nail, horn and hoof bymicroorganisms.
Isiaka A. Adelere, Agbaje Lateef
doaj  

A Unique Expression of Keratin 14 in a Subset of Trophoblast Cells. [PDF]

open access: yesPLoS ONE, 2015
The placenta, a transient organ in human, is essential for pregnancy maintenance and for fetal growth and development. Trophoblast and stromal cells are the main cell types present in human placenta.
Wassim Abou-Kheir   +4 more
doaj   +1 more source

Keratins Mediate Localization of Hemidesmosomes and Repress Cell Motility [PDF]

open access: yes, 2013
The keratin (K)–hemidesmosome (HD) interaction is crucial for cell-matrix adhesion and migration in several epithelia, including the epidermis. Mutations in constituent proteins cause severe blistering skin disorders by disrupting the adhesion complex ...
Roth, Wera   +6 more
core   +1 more source

Single‐Cell Profiling Reveals a Protective WNT5A‐ATF3‐FOSB Signaling Axis in Hair Follicle Stem Cells During Androgenetic Alopecia

open access: yesAdvanced Science, EarlyView.
Androgenetic alopecia (AGA) is a common form of hair loss with limited treatment options. Silencing of WNT5A signaling, which is widely known as the trigger of the ncWNT signaling pathway, happens in hair follicle stem cells from balding areas. It leads to downregulation of ATF3 and its target FOSB.
Ruiyu Luo   +10 more
wiley   +1 more source

Characterization and profiling of human hair keratins

open access: yes, 2022
Human hair is a naturally-occurring fibrous material, and distinctions in human hair characteristics of individuals are associated with variations at the molecular level.
Leung, Ching Yung
core  

A Multiscale Mechanistic Framework for Polydopamine Dyeing in Ultrablack Wool Textiles

open access: yesAdvanced Science, EarlyView.
Ultrablack photonic textiles are enabled through polydopamine (PDA) dyeing, which is governed by the interplay of PDA chemistry, wool surface topology and chemistry, and hierarchical fiber–yarn–fabric architecture. Fabric architecture emerges as a primary and previously underappreciated design lever for wide‐angle optical performance.
Hansadi Jayamaha   +4 more
wiley   +1 more source

Evolutionary origin of Hoxc13-dependent skin appendages in amphibians

open access: yesNature Communications
Cornified skin appendages, such as hair and nails, are major evolutionary innovations of terrestrial vertebrates. Human hair and nails consist largely of special intermediate filament proteins, known as hair keratins, which are expressed under the ...
Marjolein Carron   +10 more
doaj   +1 more source

Marcadores de hiperproliferação na epiderme do meato acústico externo Hyperproliferation markers in ear canal epidermis

open access: yesBrazilian Journal of Otorhinolaryngology, 2010
Vários estudos envolvendo métodos imunoistoquímicos para avaliação da epiderme do meato acústico externo já foram realizados com os mais diversos objetivos.
João Daniel Caliman e Gurgel   +3 more
doaj   +1 more source

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