Results 41 to 50 of about 56,206 (306)

Keratin 17 Suppresses Cell Proliferation and Epithelial-Mesenchymal Transition in Pancreatic Cancer

Frontiers in Medicine, 2020
Keratin 17 (K17), a member of type I acidic epithelial keratin family, has been reported to be upregulated in many malignant tumors and to be involved in promoting the development of tumors.
Yong Zeng, Min Zou, Yan Liu, Keting Que, Yunbing Wang, Changan Liu, Jianpin Gong, Yu You   +7 more
doaj   +1 more source

Rhabdomyosarcoma of the skull with fusion and ALK and cytokeratin expression: a case report [PDF]

Journal of Pathology and Translational Medicine
Rhabdomyosarcoma (RMS) comprises of heterogeneous group of neoplasms that occasionally express epithelial markers on immunohistochemistry (IHC). We herein report the case of a patient who developed RMS of the skull with EWSR1 fusion and anaplastic ...
Hyeong Rok An, Kyung-Ja Cho, Sang Woo Song, Ji Eun Park, Joon Seon Song   +4 more
doaj   +1 more source

Carbamoylated Nail Proteins as Assessed by Near-Infrared Analysis Are Associated with Load of Uremic Toxins and Mortality in Hemodialysis Patients

Toxins, 2020
Carbamoylation is an important risk factor for accelerated atherogenesis and mortality in patients undergoing hemodialysis (HD). We intended to explore whether carbamoylation as assessed by near-infrared (NIR) analysis of nail proteins is associated with
Sander De Bruyne, Jonas Himpe, Sigurd E. Delanghe, Griet Glorieux, Wim Van Biesen, Marc L. De Buyzere, Marijn M. Speeckaert, Joris R. Delanghe   +7 more
doaj   +1 more source

Keratins as components of the enamel organic matrix

Matrix Biology, 2015
Dental enamel is a hardest tissue in the human body, and although it starts as a tissue rich in proteins, by the time of eruption of the tooth in the oral cavity only a small fraction of the protein remains. While this organic matrix of enamel represents
O. Duverger, E. Beniash, M. Morasso
semanticscholar   +1 more source

Methods of keratin extraction from wool and hair and prospects of their application in biomedicine and bioengineering

Біологічні студії, 2019
The present article gives the overview of scientific information on the hair structure, the structural and functional properties of keratins, and methods of their extracting from the natural fibers.
V. V. Mykhaliuk, V. V. Havryliak
doaj   +1 more source

Evaluation of expression of Toll-Like Receptors 7 and 9, proliferation, and cytoskeletal biomarkers in plaque and guttate psoriasis: A pilot morphological study

European Journal of Histochemistry, 2021
This pilot study was aimed at comparing TLR7/TLR9 expression, cytoskeletal arrangement, and cell proliferation by indirect immunofluorescence in parallel lesional and non lesional skin samples of guttate psoriasis (PG) and psoriasis vulgaris (PV) in five
Francesca Prignano, Giulia Lombardo, Serena Indino, Federica Ricceri, Laura Cornaghi, Elena B. Donetti   +5 more
doaj   +1 more source

Obtaining human hair keratin-based films and their characteristics

Біологічні студії, 2021
Background. Keratins are natural biopolymers with a wide range of applications in the field of biotechnology. Materials and Methods. Extraction of keratins was performed by a modified Nakamura method using 250 mM DTT.
V. V. Mykhaliuk, V. V. Havryliak
doaj   +1 more source

New consensus nomenclature for mammalian keratins

Journal of Cell Biology, 2006
Keratins are intermediate filament–forming proteins that provide mechanical support and fulfill a variety of additional functions in epithelial cells. In 1982, a nomenclature was devised to name the keratin proteins that were known at that point.
J. Schweizer, P. Bowden, P. Coulombe, L. Langbein, E. Lane, T. Magin, L. Maltais, M. Omary, D. Parry, M. Rogers, M. Wright   +10 more
semanticscholar   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source