Response of xenografts of developing human female reproductive tracts to the synthetic estrogen, diethylstilbestrol. [PDF]
Human female fetal reproductive tracts 9.5-22 weeks of gestation were grown for 1 month in ovariectomized athymic adult female mouse hosts that were either untreated or treated continuously with diethylstilbestrol (DES) via subcutaneous pellet.
Baskin, Laurence +5 more
core +2 more sources
Mass spectrometry data from proteomic analysis of human skin keratins after exposure to UV radiation
A mass spectrometry (MS)-based proteomic methodology was employed to monitor oxidative modifications in keratins, the main constituents of human skin (“Non-invasive proteomic analysis of human skin keratins: screening of methionine oxidation in keratins ...
Seon Hwa Lee +3 more
doaj +1 more source
A keratin scaffold regulates epidermal barrier formation, mitochondrial lipid composition, and activity. [PDF]
Keratin intermediate filaments (KIFs) protect the epidermis against mechanical force, support strong adhesion, help barrier formation, and regulate growth.
Adams +140 more
core +1 more source
Significance of stress keratin expression in normal and diseased epithelia
Summary: A group of keratin intermediate filament genes, the type II KRT6A-C and type I KRT16 and KRT17, are deemed stress responsive as they are induced in keratinocytes of surface epithelia in response to environmental stressors, in skin disorders (e.g.
Erez Cohen +7 more
doaj +1 more source
Keratin 17 Suppresses Cell Proliferation and Epithelial-Mesenchymal Transition in Pancreatic Cancer
Keratin 17 (K17), a member of type I acidic epithelial keratin family, has been reported to be upregulated in many malignant tumors and to be involved in promoting the development of tumors.
Yong Zeng +7 more
doaj +1 more source
Rhabdomyosarcoma of the skull with fusion and ALK and cytokeratin expression: a case report [PDF]
Rhabdomyosarcoma (RMS) comprises of heterogeneous group of neoplasms that occasionally express epithelial markers on immunohistochemistry (IHC). We herein report the case of a patient who developed RMS of the skull with EWSR1 fusion and anaplastic ...
Hyeong Rok An +4 more
doaj +1 more source
Utility of Keratins as Biomarkers for Human Oral Precancer and Cancer
Human oral cancer is the single largest group of malignancies in the Indian subcontinent and the sixth largest group of malignancies worldwide. Squamous cell carcinomas (SCC) are the most common epithelial malignancy of the oral cavity, constituting over
Milind Vaidya +2 more
doaj +1 more source
Sedimentation Studies of Epidermal Keratins. Keratin A and Keratin B [PDF]
Electrophoretically homogeneous keratin A and keratin B were studied in the ultracentrifuge. Both preparations revealed two fractions: one which sedimented rapidly and another which sedimented slowly. This indicated that both preparations are heterogeneous with respect to particle size.
openaire +2 more sources
The present article gives the overview of scientific information on the hair structure, the structural and functional properties of keratins, and methods of their extracting from the natural fibers.
V. V. Mykhaliuk, V. V. Havryliak
doaj +1 more source
Human hair keratins were among the first to be studied but it is only recently that sufficient information has been obtained to gain a basic biologic perspective of these proteins. Hair keratins are members of the intermediate filament family of proteins, yet are sufficiently divergent from epidermal keratins to warrant separate classification: type Ia
J, Yu +4 more
openaire +2 more sources

