Results 11 to 20 of about 56,206 (306)
Keratins 6, 16, and 17 in Health and Disease: A Summary of Recent Findings
Current Issues in Molecular BiologyKeratins 6, 16, and 17 occupy unique positions within the keratin family. These proteins are not commonly found in the healthy, intact epidermis, but their expression increases in response to damage, inflammation, and hereditary skin conditions, as well ...
Daniil D. Romashin +5 more
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Utility of Keratins as Biomarkers for Human Oral Precancer and Cancer
Life, 2022 Human oral cancer is the single largest group of malignancies in the Indian subcontinent and the sixth largest group of malignancies worldwide. Squamous cell carcinomas (SCC) are the most common epithelial malignancy of the oral cavity, constituting over
Milind Vaidya +2 more
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The human keratins: biology and pathology
Histochemistry and Cell Biology, 2008 The keratins are the typical intermediate filament proteins of epithelia, showing an outstanding degree of molecular diversity. Heteropolymeric filaments are formed by pairing of type I and type II molecules.
Roland Moll +2 more
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Frontiers in Medicine, 2022 BackgroundOnychopapilloma is generally recognized as a benign tumor of the nail bed and distal matrix. However, the origin of onychopapilloma has not been explained yet.ObjectiveTo clarify the origin of onychopapilloma, we detected the expression ...
Mengxi Liu +8 more
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Methods in Enzymology, 2016 Keratins comprise the type I and type II intermediate filament-forming proteins and occur primarily in epithelial cells. They are encoded by 54 evolutionarily conserved genes (28 type I, 26 type II) and regulated in a pairwise and tissue type-, differentiation-, and context-dependent manner.
Fengrong, Wang +2 more
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Keratins in health and cancer: more than mere epithelial cell markers
Oncogene, 2010 Keratins are the intermediate filament (IF)-forming proteins of epithelial cells. Since their initial characterization almost 30 years ago, the total number of mammalian keratins has increased to 54, including 28 type I and 26 type II keratins.
V. Karantza
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Quantifying cytoskeletal protein interactions with far Western blotting [PDF]
Frontiers in Molecular BiosciencesThe study of cytoskeletal proteins has been limited by some of their intrinsic properties, such as fixed intracellular localization and insolubility, which limit the implementation of many protein–protein interaction assays.
Marcelo M. Melo +4 more
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Extraction of keratin particles as intact protein sequences from chicken feathers and their characterization [PDF]
Biomaterials and BiosystemsKeratins are ubiquitously occurring proteins, which are the structural basis of e.g. hairs, nails, and even skin. In detail, the Stratum corneum (SC) barrier function depends on the keratin-filled corneocytes and the surrounding lipid matrix.
Julia Chuttke +6 more
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Hepatocyte Thorns, A Novel Drug-Induced Stress Response in Human and Mouse Liver Spheroids
Cells, 2022 The in vivo-relevant phenotype of 3D liver spheroids allows for long-term studies of, e.g., novel mechanisms of chronic drug-induced liver toxicity.
Chris S. Pridgeon +7 more
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The comparative analysis of the methods for keratin extraction from sheep wool and human hair
Біологія тварин, 2020 Nowadays, biopolymers such as keratins are widely used in biomedicine due to their low toxicity, biocompatibility, and biodegradability. At the molecular level, keratins differ from other structural proteins by a high content of disulfide bonds, which ...
V. Havryliak, V. Mykhaliuk
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