Results 11 to 20 of about 16,177 (263)
Frontiers in Medicine, 2022 BackgroundOnychopapilloma is generally recognized as a benign tumor of the nail bed and distal matrix. However, the origin of onychopapilloma has not been explained yet.ObjectiveTo clarify the origin of onychopapilloma, we detected the expression ...
Mengxi Liu +8 more
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Utility of Keratins as Biomarkers for Human Oral Precancer and Cancer
Life, 2022 Human oral cancer is the single largest group of malignancies in the Indian subcontinent and the sixth largest group of malignancies worldwide. Squamous cell carcinomas (SCC) are the most common epithelial malignancy of the oral cavity, constituting over
Saie Mogre, Crismita Dmello
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Extraction of keratin particles as intact protein sequences from chicken feathers and their characterization [PDF]
Biomaterials and BiosystemsKeratins are ubiquitously occurring proteins, which are the structural basis of e.g. hairs, nails, and even skin. In detail, the Stratum corneum (SC) barrier function depends on the keratin-filled corneocytes and the surrounding lipid matrix.
Julia Chuttke +6 more
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Quantifying cytoskeletal protein interactions with far Western blotting [PDF]
Frontiers in Molecular BiosciencesThe study of cytoskeletal proteins has been limited by some of their intrinsic properties, such as fixed intracellular localization and insolubility, which limit the implementation of many protein–protein interaction assays.
Marcelo M. Melo +4 more
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Keratins 6, 16, and 17 in Health and Disease: A Summary of Recent Findings
Current Issues in Molecular BiologyKeratins 6, 16, and 17 occupy unique positions within the keratin family. These proteins are not commonly found in the healthy, intact epidermis, but their expression increases in response to damage, inflammation, and hereditary skin conditions, as well ...
Alexander Rusanov +2 more
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Hepatocyte Thorns, A Novel Drug-Induced Stress Response in Human and Mouse Liver Spheroids
Cells, 2022 The in vivo-relevant phenotype of 3D liver spheroids allows for long-term studies of, e.g., novel mechanisms of chronic drug-induced liver toxicity.
Chris S. Pridgeon +7 more
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The comparative analysis of the methods for keratin extraction from sheep wool and human hair
Біологія тварин, 2020 Nowadays, biopolymers such as keratins are widely used in biomedicine due to their low toxicity, biocompatibility, and biodegradability. At the molecular level, keratins differ from other structural proteins by a high content of disulfide bonds, which ...
V. Havryliak, V. Mykhaliuk
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International Journal of Dermatology, 1976 Early studies have already shown that the tonofibrils of malpighian cells consist of a --SH containing fibrous alpha-protein. It was assumed that the highly resistant protective substance, keratin, was formed by the conversion of --SH groups into --S--S--bonds in this protein.
K, Fukuyama +3 more
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European Journal of Histochemistry, 2021 The urothelium, an epithelium of the urinary bladder, primarily functions as blood-urine permeability barrier. The urothelium has a very slow turn-over under normal conditions but is capable of extremely fast response to injury.
Daša Zupančič, Rok Romih
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A novel and ancient group of type I keratins with members in bichir, sturgeon and gar
Frontiers in Zoology, 2007 1. Background Vertebrate epithelial cells typically express a specific set of keratins. In teleosts, keratins are also present in a variety of mesenchymal cells, which usually express vimentin.
Neumann Sebastian +4 more
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