Results 51 to 60 of about 7,935 (200)

A Blood‐Brain Barrier‐Penetrant Ag(III) Corrole Compound Rescues Alzheimer's Disease Pathology by Targeting Aβ42‐Induced Oxidative Stress

open access: yesAdvanced Science, Volume 13, Issue 8, 9 February 2026.
The newly designed metallo‐corrole (Mor‐Cor)Ag(III) with a morpholino group exhibited promising therapeutic potential for Alzheimer's disease. It significantly reduces reactive oxygen species (ROS), decreases GFAP expression, increases neurite length, and decreases cell death compared to other similar metallo‐corroles. Abstract Alzheimer's disease (AD)
Arup Tarai   +7 more
wiley   +1 more source

Efficacy of bioflavonoid quercetin in treatment of herpetic keratitis patients with dry eye syndrome

open access: yesJournal of Ophthalmology, 2018
Introduction. Dry eye syndrome has drown a special attention of ophthalmologists not only because of its prevalence but also due to the increased frequency among patients with inflammatory processes in the cornea and conjunctiva. Purpose.
S. Ya. Rafalyuk, T.B. Gaydamaka
doaj   +1 more source

Clinical approach to corneal ulcers

open access: yesTNOA Journal of Ophthalmic Science and Research, 2023
A corneal ulcer is a break or defect in the surface epithelium of the cornea, accompanied by tissue decay in the nearby area, leading to stromal necrosis. On a pathological level, there are swelling and an influx of cells in the affected region.
Madhuvanthi Mohan   +3 more
doaj   +1 more source

Corneal Allograft Rejection: Immunopathogenesis to Therapeutics [PDF]

open access: yes, 2014
Corneal transplantation is among the most successful solid organ transplants. However, despite low rejection rates of grafts in the ‘low-risk’ setting, rejection can be as high as 70% when grafted into ‘high-risk’ recipient beds. Under normal homeostatic
Hamrah, Pedram, Qazi, Yureeda
core   +1 more source

Applications of Multifunctional Hydrogel in Tissue Engineering and Regenerative Medicine

open access: yesMedComm, Volume 7, Issue 2, February 2026.
Schematic illustration showing multifunctional hydrogels in the application of tissue engineering and regenerative medicine. ABSTRACT Hydrogels, with excellent hydrophilicity and high‐water content, have emerged as highly versatile biomaterials for tissue engineering and regenerative medicine.
Jieran Lyu   +4 more
wiley   +1 more source

Genetic diversity of Acanthamoeba and clinical outcome predictors in Danish patients with Acanthamoeba keratitis

open access: yesActa Ophthalmologica, Volume 104, Issue 1, Page 44-51, February 2026.
Abstract Purpose Acanthamoeba keratitis (AK) is a severe corneal infection with potential detrimental effects on visual outcome and quality of life, primarily affecting young contact lens wearers. We report Acanthamoeba genotypes, subtypes and clinical outcome from Danish patients with AK. Methods Thirty‐nine PCR‐positive AK cases diagnosed and treated
Sandra M. Skovdal   +5 more
wiley   +1 more source

Síndrome poliglandular autoimune tipo 1: descrição de caso e revisão da literatura [PDF]

open access: yes, 2012
Autoimmune polyendocrine syndrome type 1 (APECED) is a rare autosomal recessive disorder characterized by autoimmune multiorgan attack. The disease is caused by mutations in the autoimmune regulator gene (AIRE), resulting in defective AIRE protein, which
Dias-da-Silva, Magnus Régios   +2 more
core   +2 more sources

Progressive Insights into 3D Bioprinting for Corneal Tissue Restoration

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 3, 19 January 2026.
This review explores the potential of 3D bioprinting to replicate the complex structure and function of the human cornea. It highlights key advances in bioink development, printing modalities, and in vivo performance, while addressing current challenges and emerging strategies. The review emphasizes bioprinting's promise to overcome donor shortages and
Ilayda Namli   +6 more
wiley   +1 more source

Topical Liposomal Ozonated Oil in Complicated Corneal Disease: A Report on Three Clinical Cases

open access: yesInternational Medical Case Reports Journal, 2021
Fedele Passidomo,1 Francesco Pignatelli,1 Giuseppe Addabbo,1 Ciro Costagliola2 1Comprehensive Ophthalmology Unit, S.S. Annunziata Hospital, Taranto, Italy; 2Department of Medicine and Health Sciences “V.
Passidomo F   +3 more
doaj  

Effect of bioflavonoid quercetin on the course of inflammatory process in herpetic keratitis patients with dry eye syndrome

open access: yesJournal of Ophthalmology, 2016
Backup: The problem of dry eye syndrome is of great importance and significance in ophthalmology. The purpose of the present paper was to study the effect of Lipoflavon on the course of inflammatory process in herpetic keratitis (HK ) patients with ...
S. Ya. Rafalyuk
doaj   +1 more source

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