Results 1 to 10 of about 43,882 (243)

Single-cell atlas of keratoconus corneas revealed aberrant transcriptional signatures and implicated mechanical stretch as a trigger for keratoconus pathogenesis

Cell Discovery, 2022
Keratoconus is a common ectatic corneal disorder in adolescents and young adults that can lead to progressive visual impairment or even legal blindness. Despite the high prevalence, its etiology is not fully understood. In this study, we performed single-
Shengqian Dou, Qun Wang, Bin Zhang, Chao Wei, Huijin Wang, Ting Liu, Haoyun Duan, Hui Jiang, Mingna Liu, Xiaolin Qi, Qingjun Zhou, Lixin Xie, Weiyun Shi, Hua Gao   +13 more
doaj   +2 more sources

Prevalence and risk factors of keratoconus (including oxidative stress biomarkers) in a cohort study of Shiraz university of medical science employees in Iran

BMC Ophthalmology, 2023
Background To determine the prevalence of keratoconus in Shiraz University of Medical Sciences Employees and the related risk factors including oxidative stress biomarkers. Methods 2546 subjects’ mean age ± SD, 40.35 ± 6.70 (46% male) were recruited. All
Sahar Mohaghegh, Haleh Kangari, Seyed Jalil Masoumi, Shahram Bamdad, Saeed Rahmani, Saeed Abdi, Nagham Fazil, Saeedeh Shahbazi   +7 more
doaj   +2 more sources

Keratoconus epidemiology

Saudi Journal of Ophthalmology, 2022
Keratoconus is an ectatic corneal disease that affects both men and women, usually at a young age. Risk factors such as eye rubbing, environmental and genetic factors contribute to its pathogenesis. Keratoconus presents a variable prevalence, being as high as 5% of the population in the Middle East.
Gomes, José A. P., Rodrigues, Pablo F., Lamazales, Luiz L.   +2 more
openaire   +3 more sources

The correlation between keratoconus and eye rubbing: a review [PDF]

International Journal of Ophthalmology, 2019
Keratoconus is a non-inflammatory disorder which is gradual in development; corneal thinning and ectatic protrusion characterizes it. Keratoconus prevalence varies between different regions depending on several factors that affecting its prevalence ...
Hatim Najmi, Yara Mobarki, Khalid Mania, Bashaer Altowairqi, Mohammed Basehi, Mohammed Salih Mahfouz, Mona Elmahdy   +6 more
doaj   +2 more sources

Contrast sensitivity and higher-order aberrations in Keratoconus subjects

Scientific Reports, 2021
This study analyzes the relationship between contrast-sensitivity and higher-order aberrations (HOA) in mild and subclinical-keratoconus in subjects with good visual-acuity (VA).
Einat Shneor, David P. Piñero, Ravid Doron   +2 more
doaj   +2 more sources

Challenges in Biometry and Intraocular Lens Power Calculations in Keratoconus: A Review [PDF]

Diagnostics
Purpose: The purpose of this work was to conduct a comprehensive literature review of the challenges encountered in ocular biometry and intraocular lens (IOL) power calculations in patients with keratoconus undergoing cataract surgery and to evaluate the
Mayank A. Nanavaty
doaj   +2 more sources

New Keratoconus Risk Factors: A Cross-Sectional Case—Control Study

Journal of Ophthalmology, 2022
Purpose. To evaluate risk factors associated with keratoconus in a monocentric cross-sectional case-control study. Methods. This observational study occurred from June 2019 to February 2021 in a university hospital (France).
Eloi Debourdeau, Gabriel Planells, Chloe Chamard, David Touboul, Max Villain, Pascal Demoly, Fanny Babeau, Pierre Fournie, Vincent Daien   +8 more
doaj   +1 more source

Anterior segment characteristics in normal and keratoconus eyes evaluated with a new type of swept-source optical coherence tomography.

PLoS ONE, 2022
PurposeThis study aimed to evaluate and compare the discriminating ability of corneal elevation maps generated using a swept-source optical coherence tomography (SS-OCT) (SS-OCT ANTERION, Heidelberg Engineering, Heidelberg, Germany), which was estimated ...
Kook Young Kim, Seongjun Lee, Young Joon Jeon, Ji Sang Min   +3 more
doaj   +1 more source

In-vivo corneal biomechanical analysis of unilateral keratoconus [PDF]

International Journal of Ophthalmology, 2015
AIM: To evaluate and compare corneal biomechanical findings measured by ocular response analyzer, topographic and pachymetric findings in patients with unilateral keratoconus patients and healthy controls. METHODS: This is an observational, case-control
Orhan Ayar, Mehmet Cuneyt Ozmen, Orkun Muftuoglu, Mehmet Orcun Akdemir, Mustafa Koc, Kemal Ozulken   +5 more
doaj   +1 more source

Keratoconus International Consortium (KIC)- advancing keratoconus research

BMC Ophthalmology, 2023
Abstract Clinical relevance The Keratoconus International Consortium (KIC) will allow better understanding of keratoconus. Background Keratoconus is a disorder characterised by corneal elevation and thinning, leading to reduced vision.
Srujana Sahebjada, Elsie Chan, Gerard Sutton, Chi Pui Pang, Chris Hodge, Elaine Chong, Mostefa Fodil, Steve Wiffen, Grant R Snibson, Nigel Morlet, Chameen Samarawickrama, John Males, Richard K. Lee, Peter Beckingsale, Kathryn P. Burdon, Vishal Jhanji, Pravin V. Krishna, Colin Chan, Abi Tenen, Athena Roufas, Tess Huynh, Rasik B Vajpayee, Aanchal Gupta, Mario Laelio Alves Silva, Mehran Zarei, S. Senthil Kumaran, Guofu Huang, Berthold Seitz, Shengwei Ren, Charles N. J. McGhee, N H Barker, Yves Kerdraon, Sundaram Natarajan, Wafaa Meteoukki, Andrea Y. Ang, Mark Daniell, Paul Mitchell   +36 more
openaire   +4 more sources