Results 41 to 50 of about 21,195 (193)

Costello Syndrome and Ophthalmologic Issues: Unveiling the Unseen

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Costello syndrome (CS) is an ultra‐rare condition belonging to the RASopathies, a group of disorders characterized by aberrant RAS/MAPK pathway signaling, which is involved in ocular development and in some eye pathologies. However, only a few studies assessing the ophthalmic features of individuals with CS are available.
Sofia Peschiaroli, Germana Viscogliosi, Annabella Salerni, Emanuele Crincoli, Roberta Mattei, Tommaso Verdolotti, Serafina Antonella Loprete, Valentina Trevisan, Giovanni Antonio Marrocco, Alessia Cherubino, Lucrezia Perri, Roberta Onesimo, Giuseppe Zampino, Chiara Leoni   +13 more
wiley   +1 more source

Clinical and social portrait of patients with Keratoconus, living in the southern regions of Russia

Офтальмохирургия, 2019
For the southern regions of Russia, the problem of Keratoconus is of particular importance due to the high incidence of the disease.Purpose. To examine the clinical and social characteristics of patients with Keratoconus and get a portrait of the disease.
E. V. Podtynnyh, S. B. Izmailova, E. N. Komarovskikh   +2 more
doaj   +1 more source

A new Method for the in vivo identification of material properties of the human eye. Feasibility analysis based on synthetic data [PDF]

arXiv, 2021
This paper proposes a new method for in vivo and almost real-time identification of biomechanical properties of the human cornea based on non-contact tonometer data. Further goal is to demonstrate the method's functionality based on synthetic data serving as reference.
arxiv  

Distribution of pediatric keratoconus by different age and gender groups

Frontiers in Pediatrics, 2022
PurposeTo evaluate the distribution of pediatric keratoconus patients and the disease severity based on different age and gender groups in China.Materials and methodsA total of 446 keratoconus eyes in 266 pediatric patients from January 2019 to January ...
Kaili Yang, Yuwei Gu, Liyan Xu, Qi Fan, Meng Zhu, Qing Wang, Shanshan Yin, Bo Zhang, Chenjiu Pang, Shengwei Ren   +9 more
doaj   +1 more source

Deep Learning Based Unsupervised and Semi-supervised Classification for Keratoconus [PDF]

arXiv, 2020
The transparent cornea is the window of the eye, facilitating the entry of light rays and controlling focusing the movement of the light within the eye. The cornea is critical, contributing to 75% of the refractive power of the eye. Keratoconus is a progressive and multifactorial corneal degenerative disease affecting 1 in 2000 individuals worldwide ...
arxiv  

Compact orthogonal view OCT: clinical exploration of human trabecular meshwork and cornea at cell resolution [PDF]

arXiv, 2022
Glaucoma remains among the leading causes of blindness despite many treatment options available today. Effective treatment requires early diagnosis, which is difficult to achieve with existing imaging technologies that detect the already inflicted irreversible posterior eye damage.
arxiv  

Shear Wave Optical Coherence Elastography and Structural Analysis of the Postnatal Mouse Cornea through Development

Journal of Biophotonics, EarlyView.
This paper investigates the geometrical and biomechanical properties of neonatal eyes at the early stages of development. We found that the corneal thickness is uncoupled from elastic wave speed and that the content and organization of the cornea primarily influence its mechanical properties.
Andrew L. Lopez III, Mohammad Dehshiri, Alexander W. Schill, Salavat Aglyamov, Kirill Larin   +4 more
wiley   +1 more source

Association of single nucleotide variants in the COL5A1 gene and adjacent intergenic space with keratoconus in a cohort of patients from Russia

Офтальмохирургия, 2020
Purpose. To assess an association of markers near the COL5A1 gene and in its intron with keratoconus. To study the relationship between the presence of marker alleles and the level of expression of the COL5A1 gene in the cornea of patients with ...
L. O. Skorodumova, A. V. Belodedova, E. S. Zakharova, Е. I. Sharova, M. M. Bikbov, E. L. Usubov, O. P. Antonova, B. E. Malyugin   +7 more
doaj   +1 more source

Assessing UVA and Laser‐Induced Crosslinking via Brillouin Microscopy

Journal of Biophotonics, EarlyView.
UVA crosslinking is the primary treatment to combat keratoconus. Nevertheless, unwanted side effects and limitations due to nonselective irradiation lead to the investigation of alternative irradiation treatments. This study shows similar changes in the Brillouin frequency shift of corneas crosslinked with UVA irradiation and a NIR femtosecond laser ...
Christian A. Iriarte‐Valdez, Johannes Wenzel, Emilie Baron, Alexandra Y. Claus, Stefan Kalies, Karsten Sperlich, Oliver Stachs, Maria Leilani Torres‐Mapa, Alexander Heisterkamp   +8 more
wiley   +1 more source

Hypothyroidism is Not Associated with Keratoconus Disease: Analysis of 626 Subjects

Journal of Ophthalmology, 2019
Purpose. To analyze the association between hypothyroidism and keratoconus, we examined blood thyroid hormone levels and corneal tomographic parameters in healthy subjects and patients with keratoconus. Methods.
Zsuzsa Flaskó, Elena Zemova, Timo Eppig, László Módis, Achim Langenbucher, Stefan Wagenpfeil, Berthold Seitz, Nóra Szentmáry   +7 more
doaj   +1 more source