Results 51 to 60 of about 8,061 (176)

Incidence of cutaneous lupus erythematosus and systemic progression: A Nationwide study in Korea

Journal of the European Academy of Dermatology and Venereology, EarlyView.
This nationwide study reports a cutaneous lupus erythematosus (CLE) incidence of 3.98/100,000 person‐years. CLE was associated with an increased risk of actinic keratosis and skin cancer. Progression to SLE clustered within 5 years after CLE diagnosis, with a 5‐year cumulative incidence of 11.4%, supporting a risk‐stratified follow‐up approach during ...
Seon Young Song, Jiyeong Kim, Yu‐Mi Kim, Joo Yeon Ko   +3 more
wiley   +1 more source

Multidisciplinary Delphi Consensus Between Primary Care and Dermatology on Updated Management of Actinic Keratosis in Spain

Actas Dermo-Sifiliográficas
Actinic keratosis is a skin disease with the potential to progress to cutaneous squamous cell carcinoma, making its treatment essential. However, the last update of the Spanish adaptation of the European clinical guidelines dates back to 2014.
L. Ferrándiz, J.A. Heras-Hitos, P. Casas Rodríguez, A. Valcarce-Leonisio, O. San Martín, R. Ruiz-Villaverde   +5 more
doaj   +1 more source

Simulated daylight versus conventional PDT for mild to moderate actinic keratoses: A randomized controlled trial

Journal of the European Academy of Dermatology and Venereology, EarlyView.
This single‐centre, randomized controlled trial showed that simulated daylight photodynamic therapy (SDL‐PDT, n = 785 lesions) was less effective than conventional photodynamic therapy (C‐PDT, n = 673 lesions) in treating mild to moderate actinic keratoses with 1‐year clearance rates of 71.0% for SDL‐PDT versus 85.3% for C‐PDT (p < 0.001). However, SDL‐
Alexandra Sjöholm, Eva Backman, Maja Modin, Julia Fougelberg, Magdalena Claeson, John Paoli   +5 more
wiley   +1 more source

Cardiovascular Drug Use and Risk of Actinic Keratosis: A Case-Control Study

Dermatology and Therapy, 2020
Introduction Actinic keratosis (AK) is a precancerous skin lesion. Currently, many experts treat actinic keratosis as squamous cell carcinoma in situ. It is well established that exposure of the skin to ultraviolet radiation is a major risk factor for ...
Olga Warszawik-Hendzel, Małgorzata Olszewska, Adriana Rakowska, Mariusz Sikora, Piotr Hendzel, Lidia Rudnicka   +5 more
doaj   +1 more source

Prospective subtyping of head and neck basal cell carcinoma by dermoscopy and handheld RCM

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Handheld reflectance confocal microscopy, alone or with dermoscopy, increases specificity, maintains high sensitivity and improves diagnostic confidence for head and neck basal cell carcinoma. It may offer a non‐invasive alternative to confirmatory biopsies when planning micrographically controlled surgery in clinically high‐risk cases.
Yannick S. Elshot, Wouter Ouwerkerk, Biljana Zupan‐Kajcovski, Mijke Bol, Erienne M. V. de Cuba, Lies H. Jaspars, Giulia Briatico, Giuseppe Argenziano, Nicole A. Kukutsch, Salvador Gonzalez, Manu Jain, Marianne B. Crijns, Alfons J. M. Balm, W. Martin C. Klop, Marcel W. Bekkenk, Menno A. de Rie   +15 more
wiley   +1 more source

Immune-mediated changes in actinic keratosis following topical treatment with imiquimod 5% cream

Journal of Translational Medicine, 2007
Background The objective of this study was to identify the molecular processes responsible for the anti-lesional activity of imiquimod in subjects with actinic keratosis using global gene expression profiling.
Raghavan Shalini, Jin Jizhong, Bulbulian Barbara J, Miller Richard L, Anders Makala, Storey Leslie, Torres Abel, Lee James, Slade Herbert B, Birmachu Woubalem   +9 more
doaj   +1 more source

An Unusual Case of Perineural Infiltration and Orbital Invasion of Squamous Cell Carcinoma Associated with Actinic Keratosis

Case Reports in Ophthalmological Medicine, 2020
Actinic keratosis is considered a precancerous lesion, constituting a precursor to squamous cell carcinoma (SCC) formation. Perineural invasion has been observed in patients with cutaneous carcinoma due to local subcutaneous tissue destruction and ...
Edgard Farah, Marie Callet, Augustin Leclerc, Tryfon Rotsos, Chrysanthos Symeonidis, Pierre-Vincent Jacomet, Olivier Galatoire   +6 more
doaj   +1 more source

A Retrospective Analysis of the Diagnostic Accuracy in Diagnosing OPMD and Benign Oral Lesions

Oral Diseases, EarlyView.
ABSTRACT Objective The clinical suspicion of a neoplastic lesion necessitates prompt diagnostic assessment through oral biopsy. However, the failure to accurately recognize an oral potentially malignant disorder (OPMD) or the misdiagnosis of a benign lesion can lead to diagnostic delays with significant impact on the patient's health.
Griselda Pedroso Acosta, Lucio Torelli, Theodora Magdalena Bogdan Preda, Roberto Di Lenarda, Matteo Biasotto, Katia Rupel, Giulia Ottaviani   +6 more
wiley   +1 more source

Zebrafish as a practical and convenient model for the study of photodynamic and photothermal therapy of solid tumors: A scoping review

Photochemistry and Photobiology, EarlyView.
Zebrafish provide a high‐throughput, optically transparent platform for cancer and drug screening. Their ~80% genetic homology, xenograft compatibility, and transgenic strains enable targeted photosensitizer screening, real‐time ROS and tumor imaging, and mechanistic assays, while fish embryo acute toxicity (FET) and in vitro tests streamline toxicity ...
Ethan Wilson, Alexander Fiorentino, Brian W. Booth, Valery Bliznyuk, Diana Ivankovic, Luigi Boccuto   +5 more
wiley   +1 more source

Explainable Deep Learning for Imaging‐Based Skin Lesion Diagnosis: A Systematic Literature Review

Concurrency and Computation: Practice and Experience, Volume 38, Issue 16, August 2026.
ABSTRACT In the latest years, the use of Deep Learning (DL) in imaging‐based skin lesion diagnosis has become increasingly prevalent. The deep models have revolutionized the computer‐aided diagnosis systems in terms of performance. However, DL models are often criticized as black boxes due to their complex and opaque internal design of numerous ...
Rym Dakhli, Walid Barhoumi
wiley   +1 more source