Results 61 to 70 of about 16,398 (212)

Genomic instability in human actinic keratosis and squamous cell carcinoma [PDF]

, 2011
OBJECTIVE: To compare the repetitive DNA patterns of human actinic keratoses and squamous cell carcinomas to determine the genetic alterations that are associated with malignant transformation. INTRODUCTION: Cancer cells are prone to genomic instability,
CABRAL, Luciana Sanches, FESTA NETO, Cyro, RUIZ, Itamar R. G., SANCHES JR, José A.   +3 more
core   +4 more sources

Non‐Invasive Scalp Tape‐Strip RNA Sequencing Captures Disease Activity and Treatment‐Response Signatures in Alopecia Areata

Allergy, EarlyView.
Non‐invasive scalp tape‐strip RNA sequencing captures core immune and follicular molecular signatures in alopecia areata. Tape‐strip transcriptomic profiles reflect disease severity and treatment response to baricitinib, with concordance to scalp biopsy‐derived signatures.
Carmen Mochón‐Jiménez, Jesús Gay‐Mimbrera, Viviana Dávila‐Flores, Helen He, Jerry Zhou, Irene Rivera‐Ruiz, Pedro J. Gómez‐Arias, Juan de Luque‐Fernández, Benjamin Ungar, Emma Guttman‐Yassky, Juan Ruano   +10 more
wiley   +1 more source

Actinic keratosis – diagnostic and therapeutic recommendations of the Polish Dermatological Society

Przegląd Dermatologiczny
Actinic keratosis is a common skin condition that has the potential to develop into malignant neoplastic lesions. Factors that are known to increase the likelihood of developing actinic keratosis include older age, male gender, UV exposure, and ...
Adam Reich, Aleksandra Lesiak, Joanna Narbutt, Agnieszka Owczarczyk-Saczonek, Maciej Pastuszczak, Michał Sobjanek, Jacek Szepietowski, Irena Walecka, Witold Owczarek   +8 more
doaj   +1 more source

Systemic toxicity to betamethasone ointment

Clinical Case Reports, 2020
Topically applied betamethasone for actinic keratosis may trigger systemic side effects. Systemic side effects of topical betamethasone may completely resolve after discontinuation of the causative agent.
Rahim Aliyev, Josef Finsterer
doaj   +1 more source

Skin Cancers in Australian Liver Transplant Recipients: Risk Factors and Histology

ANZ Journal of Surgery, EarlyView.
ABSTRACT Background Skin cancer is one of the most common comorbidities for liver transplant recipients (LTRs). Carcinogenesis is a multifaceted process: immunosuppression and personal risk factors such as smoking status, UV exposure, past history of skin cancer and family history of skin cancer can all play a significant role in determining the extent
Rohan Rajaram, Gehan Premaratne, Charlotte Tiplady, Evania Lok, Angela Li, Avik Majumdar, Robert Jones, Sally Kiu‐Huen Ng   +7 more
wiley   +1 more source

Clinical Risk Factors for Cutaneous Squamous Cell Carcinoma in Patients with Actinic Keratosis or Cutaneous Squamous Cell Carcinoma in Situ: A Retrospective Double-cohort Study

Acta Dermato-Venereologica
Actinic keratosis and cutaneous squamous cell carcinoma in situ are precancerous forms of cutaneous squamous cell carcinoma. In this single-centre retrospective study, patients with histopathologically confirmed actinic keratosis (n = 121) or cutaneous ...
Jaakko S. Knuutila, Olli Kaijala, Salla Lehto, Tero Vahlberg, Liisa Nissinen, Veli-Matti Kähäri, Pilvi Riihilä   +6 more
doaj   +1 more source

Whole-exome sequencing validates a preclinical mouse model for the prevention and treatment of cutaneous squamous cell carcinoma [PDF]

, 2017
Cutaneous squamous cell carcinomas (cSCC) are among the most common and highly mutated human malignancies. Solar UV radiation is the major factor in the etiology of cSCC. Wholeexome sequencing of 18 microdissected tumor samples (cases) derived from SKH-1
Aikseng Ooi, Alan Evans, Albena T. Dinkova-Kostova, Brandon Praslicka, Catherine A. Harwood, Charlotte M. Proby, Elena V. Knatko, Harwood, Jennings, Karin J. Purdie, Kim, Knatko, Leiter, Levine, Maureen Higgins, Sutherland, Varghese   +16 more
core   +2 more sources

Benign Keratoses With Inverted Follicular Keratosis‐Like Features in a Patient Receiving Ripretinib: A Case Report

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Inverted follicular keratosis (IFK) is a rare benign neoplasm of the follicular infundibulum and typically presents as a solitary, nonpigmented verrucous papule on the head and neck of older males and can mimic viral warts, basal cell carcinoma (BCC), or squamous cell carcinoma (SCC). We report a case of multiple benign keratoses with IFK‐like
Elsayed Ibrahim, Saira George, Peter N. Kundert, Benjamin H. Perkins, Jonathan L. Curry, Phyu P. Aung   +5 more
wiley   +1 more source

Photodynamic therapy of the surface form of basalioma and actinic keratosis with the topical administration of methyl aminolevulinate

Vestnik Dermatologii i Venerologii, 2017
Goal. To assess the efficacy of the photodynamic therapy with the external use of methyl aminolevulinate as a photosensitizer with further irradiation with visible red light with the wavelength of 630 nm in the treatment of patients suffering from a ...
A. A. Kubanova, A. A. Kubanov, I. N. Kondrakhina, N. V. Gribanov   +3 more
doaj   +1 more source

The Adverse Effects of Topical Photodynamic Therapy:a consensus review and approach to management [PDF]

, 2019
Background: Topical photodynamic therapy (PDT) is widely used to treat superficial nonmelanoma skin cancer and dysplasia, and is generally well tolerated.
Babilas P, Basset‐Seguin N, Gracia Cazaña T, Halldin CB, Ibbotson S, Kasche A, Kuijpers DI, López V, Maydan E, Miguélez A, Monfrecola G, Morton CA, Paci K, Pastor‐Nieto MA, Wiegell SR, Wolfe CM, Wolfe CM, Zheng W   +17 more
core   +2 more sources