Results 111 to 120 of about 50,745 (326)

Improving imiquimod use in cervical high‐grade squamous intraepithelial lesions: A qualitative study

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
Adequate patient counselling on imiquimod treatment, including the possible application methods and potential side effects, along with optimal guidance during treatment, contributes to a better patient experience and reduces the likelihood of early discontinuation of treatment.
Caroline L. P. Muntinga, Helena C. J. Schellekens, Charlotte G. J. Penders, Hélène van Meir, Gatske M. Nieuwenhuyzen‐De Boer, Anna J. M. van de Sande, Heleen J. van Beekhuizen, Peggy J. de Vos Van Steenwijk, Ruud L. M. Bekkers, Edith M. G. van Esch   +9 more
wiley   +1 more source

Predicting keratinocyte carcinoma in patients with actinic keratosis: development and internal validation of a multivariable risk‐prediction model†

British Journal of Dermatology, 2019
Patients with actinic keratosis (AK) are at increased risk for developing keratinocyte carcinoma (KC) but predictive factors and their risk rates are unknown.
S. Tokez, M. Alblas, Tamar Nijsten, L. Pardo, M. Wakkee   +4 more
semanticscholar   +1 more source

Insights into the clinical, platelet and genetic landscape of inherited thrombocytopenia with malignancy risk

British Journal of Haematology, EarlyView.
Inherited thrombocytopenia (IT) caused by germline variants in RUNX1, ETV6 or ANKRD26 carries a high risk of developing haematological malignancy. This study examined the clinical, platelet and molecular characteristics of 66 patients with these conditions, who carried 24 distinct genetic variants in the corresponding genes.
Ana Marín‐Quílez, Ana Sánchez‐Fuentes, Ana Zamora‐Cánovas, Pedro Luis Gómez‐González, Lorena Diaz‐Ajenjo, Rocío Benito, Agustín Rodríguez‐Alén, Teresa Sevivas, Thais Murciano, Laura Murillo, Nora V. Butta, Nuria Revilla, Rosa Campos, Paola Escribano, Jordi Esteve, Nuria Fernández‐Mosteirin, Francisca Ferrer‐Marín, Laura Hernández, Jorge Huerta‐Aragonés, Antonio León, Mónica López‐Duarte, Eugenia López, Mónica Martín‐Salces, Meritxell Nomdedeu, Raquel Oña, Irene Peláez‐Pleguezuelos, Fernando Ramos, Elena Sebastián, Claudia Serrano, Cristina Sierra‐Aisa, Rosa Vidal‐Laso, José Ramón González‐Porras, María Luisa Lozano, José María Bastida, José Rivera   +34 more
wiley   +1 more source

Expanding the Interface: Overlooked Dermatologic Disorders With Ocular Involvement

JEADV Clinical Practice, EarlyView.
A George
wiley   +1 more source

Deep Phenotyping of Pathology‐Confirmed Benign Lesions in PTEN Hamartoma Tumor Syndrome Patients

Clinical Genetics, EarlyView.
Gastrointestinal, skin, thyroid, and vascular lesions are frequently present in PTEN Hamartoma Tumor Syndrome patients with little to no difference between sexes or by index status. Early‐onset lipomas (< 20 years) may be useful for early recognition of patients, and uterine polyps should be considered for inclusion as a PHTS‐related lesion.
Ane J. Schei‐Andersen, Janneke H. M. Schuurs‐Hoeijmakers, Rachel van der Post, Arjen R. Mensenkamp, Jolanda Schieving, PTEN Study Group, Muriel A. Adank, Mirjam de Jong, Marjolijn C.J. Jongemans, Liselotte P. van Hest, Yvette van Ierland, Edward M. Leter, Maartje Nielsen, Janet R. Vos, Nicoline Hoogerbrugge   +14 more
wiley   +1 more source

Actinic Keratosis and Cutaneous Squamous Cell Carcinoma.

Deutsches Ärzteblatt International, 2019
BACKGROUND Cutaneous squamous cell carcinoma (cSCC) and its precursors, actinic keratoses (AK), are common. Physicians of multiple specialties are confronted with their treatment.
R. Gutzmer, S. Wiegand, O. Kölbl, K. Wermker, M. Heppt, C. Berking   +5 more
semanticscholar   +1 more source

Arrhythmogenic Cardiomyopathy: Towards Genotype Based Diagnoses and Management

Journal of Cardiovascular Electrophysiology, EarlyView.
To improve arrhythmogenic cardiomyopathy (ACM) patient care four pillars of ACM research are necessary. The first pillar to improve ACM is cohort studies in which the genotype‐specific natural history of disease is described, and subsequently genotype‐specific risk calculators can be developed, such as the DSP and PLN risk calculators.
Steven A. Muller, Giorgia Bertoli, Jianan Wang, Alessio Gasperetti, Moniek G. P. J. Cox, Hugh Calkins, Anneline S. J. M. te Riele, Daniel P. Judge, Mario Delmar, Richard N. W. Hauer, Gerard J. J. Boink, Marina Cerrone, J. Peter van Tintelen, Cynthia A. James   +13 more
wiley   +1 more source

The Genomic Landscape of Actinic Keratosis

Journal of Investigative Dermatology, 2021
J. Thomson, Findlay Bewicke-Copley, C. Anene, A. Gulati, A. Nagano, K. Purdie, G. Inman, C. Proby, I. Leigh, C. Harwood, Jun Wang   +10 more
semanticscholar   +1 more source

The integration of dermatology experts into primary care to assess and treat patients with skin lesions is cost‐effective: A quasi‐experimental study

Journal of the European Academy of Dermatology and Venereology, EarlyView.
The integration of dermatologist into primary care settings is cost‐effective and streamlines the management of patients with skin conditions. The cost for each additional pre‐malignancy or malignancy treated is €853 lower, and for any additional skin finding treated, €381 lower than that of the standard care pathway. Abstract Background The management
Maria Lovén, Laura Huilaja, Markus Paananen, Paulus Torkki   +3 more
wiley   +1 more source

Multi‐task AI models in dermatology: Overcoming critical clinical translation challenges for enhanced skin lesion diagnosis

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Our All‐In‐One framework for skin lesion diagnosis—Hierarchical‐Out of Distribution—Clinical Triage (HOT) model provides three outputs—(1) Hierarchical classification; (2) An Out‐of‐Distribution (OOD) alert; and (3) A clinical triage recommendation for the input clinical image of lesion.
Deval Mehta, Clare Primiero, Brigid Betz‐Stablein, Toan D. Nguyen, Yaniv Gal, Adrian Bowling, Martin Haskett, Maithili Sashindranath, Paul Bonnington, Victoria Mar, H. Peter Soyer, Zongyuan Ge   +11 more
wiley   +1 more source