Safety and efficacy of vismodegib in patients aged ≥65 years with advanced basal cell carcinoma. [PDF]
Because many patients with unresectable basal cell carcinoma (BCC) are aged ≥65 years, this study explores the efficacy and safety of vismodegib in these patients with locally advanced (la) or metastatic (m) basal cell carcinoma (BCC) in the ERIVANCE BCC
Arron, Sarah+8 more
core +2 more sources
Generalized keratosis pilaris induced by testosterone injections in patient with CHARGE syndrome
Keratosis pilaris (KP) is a common disorder of follicular keratinization characterized by keratotic follicular papules with varying degrees of perifollicular erythema.
Fares A. Alkhayal+4 more
doaj +1 more source
On Interpretability of Deep Learning based Skin Lesion Classifiers using Concept Activation Vectors
Deep learning based medical image classifiers have shown remarkable prowess in various application areas like ophthalmology, dermatology, pathology, and radiology.
Ahmed, Sheraz+5 more
core +1 more source
ROCK2/rasHa cooperation induce malignant conversion via p53 loss, elevated NF-κβ and tenascin C-associated rigidity but p21 inhibits ROCK2/NF-κβ-mediated progression [PDF]
To study ROCK2 activation in carcinogenesis, mice expressing 4-hydroxytamoxifen (4HT)- activated ROCK2 [K14.ROCKer] were crossed to mice expressing epidermal activated ras Ha [HK1.ras1205].
Greenhalgh, D.A.+3 more
core +1 more source
British Association of Dermatologists’ guidelines for the care of patients with actinic keratosis 2017 D. de Berker, J.M. McGregor, M.F. Mohd Mustapa, L.S. Exton and B.R. Hughes Bristol Dermatology Centre, University Hospitals Bristol, Bristol BS2 8HW, U.
D. Deberker+4 more
semanticscholar +1 more source
Confluent and reticulated papillomatosis of Gougerot - Carteuad: case report
Introduction: Confluent and reticulated papillomatosis is a rare dermatological disorder of the epidermis, with a benign course and uncertain etiopathogenesis, characterized by the slow and progressive appearance of brownish or pink papules with a ...
Bruno Porto Soares+4 more
doaj +1 more source
Contribution to characterization of skin field cancerization activity: morphometric, chromatin texture, proliferation, and apoptosis aspects, [PDF]
Background: A skin field cancerization is a cutaneous area with subclinical changes resultant from chronic sun exposure, with a higher predisposition to development of pre-neoplastic and neoplastic lesions.
Anna Carolina Miola+4 more
doaj +1 more source
Evaluation of Ingenol mebutate efficacy for the treatment of actinic keratosis with Antera 3D camera [PDF]
OBJECTIVE: Cumulative exposure of the skin to ultraviolet radiation promotes mutation in keratinocytes and their abnormal growth led to the formation of scaly lesions, called actinic keratoses (AKs).
Bottoni, U+5 more
core
Euphorbia-derived natural products with potential for use in health maintenance [PDF]
Euphorbia genus (Euphorbiaceae family), which is the third largest genus of angiosperm plants comprising ca. 2000 recognized species, is used all over the world in traditional medicine, especially in the traditional Chinese medicine. Members of this taxa
Adedoyin+34 more
core +4 more sources
Topical photodynamic therapy (PDT) using methyl aminolaevulinate is a noninvasive treatment option suitable to treat clinical and subclinical actinic keratosis (AK) over a large area (field cancerization).
Serge Mordon+12 more
semanticscholar +1 more source