Results 61 to 70 of about 37,023 (241)

Hypothesis: is yeast a clock model to study the onset of humans aging phenotypes? [PDF]

open access: yes, 2012
In this paper we report the growth and aging of yeast colonies derived from single cells isolated by micromanipulation and seeded one by one on separated plates to avoid growth interference by surrounding colonies.
Falcone, Claudio   +3 more
core   +3 more sources

Safety and efficacy of vismodegib in patients aged ≥65 years with advanced basal cell carcinoma. [PDF]

open access: yes, 2016
Because many patients with unresectable basal cell carcinoma (BCC) are aged ≥65 years, this study explores the efficacy and safety of vismodegib in these patients with locally advanced (la) or metastatic (m) basal cell carcinoma (BCC) in the ERIVANCE BCC
Arron, Sarah   +8 more
core   +2 more sources

Approach to Nail Pitting in Pediatric and Adolescent Patients: A Dermatology Perspective

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT This narrative review aims to discuss the etiologies of nail pitting in pediatric and adolescent patients, while providing a framework for further evaluation of possible underlying systemic conditions and their clinical findings from a dermatologic standpoint.
Elizabeth Botto   +3 more
wiley   +1 more source

Immunotherapy‐Related Cutaneous Toxicities in Melanoma: A Dermoscopic Perspective

open access: yesJEADV Clinical Practice, EarlyView.
Dermoscopy serves as a valuable tool in the everyday dermatological and oncological practice for melanoma patients, allowing for the prompt identification of immune‐related cutaneous toxicities and guiding clinicians toward appropriate therapeutic decisions.
Grażyna Kamińska‐Winciorek   +3 more
wiley   +1 more source

Overexpression of p63 Protein in Patients with Seborrheic Keratosis in the Setting of Carbohydrate Metabolism Disorders

open access: yesКубанский научный медицинский вестник, 2019
Aim. The paper studies p63 expression in patients with seborrheic keratosis in the presence or absence of carbohydrate metabolism disorders.Materials and methods. The study involved 130 patients with seborrheic keratosis.
A. К. Alexandrova, V. A. Smolyannikova
doaj   +1 more source

The molecular genetic analysis of the expanding pachyonychia congenita case collection [PDF]

open access: yes, 2014
BACKGROUND: Pachyonychia congenita (PC) is a rare autosomal dominant keratinizing disorder characterized by severe, painful, palmoplantar keratoderma and nail dystrophy, often accompanied by oral leucokeratosis, cysts and follicular keratosis.
Al-Asadi, E.   +9 more
core   +3 more sources

Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research

open access: yesMass Spectrometry Reviews, EarlyView.
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik   +3 more
wiley   +1 more source

Canal Cholesteatoma Presentation and Management: A Systematic Review and Meta‐Analysis

open access: yesOtolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To evaluate current understanding of external auditory canal cholesteatoma (EACC), its symptomatic burden, clinical features, diagnostic approach, and management strategies to reduce delays in diagnosis. Data Sources PubMed, CINAHL, COCHRANE Library, and SCOPUS.
Angelica M. Walker   +6 more
wiley   +1 more source

Application of dermoscopy in diagnosis of seborrheic keratosis, actinic keratosis and basal cell carcinoma

open access: yesPifu-xingbing zhenliaoxue zazhi, 2019
Objective: To explore the value of dermoscopy in the diagnosis of seborrheic keratosis, actinic keratosis and basal cell carcinoma. Methods: Patients which clinically diagnosed as seborrheic keratosis (108 cases), actinic keratosis (46 cases) and basal ...
Hao-bo JIANG   +5 more
doaj   +1 more source

BRAF inhibitor and hairy cell leukemia-related transient acantholytic dermatosis [PDF]

open access: yes, 2020
Grover disease (GD) is an acquired, nonfamilial, nonimmune mediated, transient or persistent acantholytic dermatosis. Herein, we present a 72-year-old man who had clinical and histopathologic findings of GD following two weeks of treatment with ...
Durkin, John R   +3 more
core  

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