Results 121 to 130 of about 114,264 (263)

Midazolam–ketamine versus dexmedetomidine–ketamine combinations for anesthesia of pediatric patients undergoing cardiac catheterization

Ain Shams Journal of Anesthesiology, 2019
Background The aim of the current study was to compare the effects of midazolam–ketamine versus dexmedetomidine–ketamine combinations on hemodynamics, sedation level, and recovery period in pediatric patients undergoing cardiac catheterization for ...
Mohammed Abdelsalam Menshawi, Hany Magdy Fahim   +1 more
doaj   +1 more source

Ketamine-Induced Apoptosis in Normal Human Urothelial Cells [PDF]

, 2016
Recreational abuse of ketamine has been associated with the emergence of a new bladder pain syndrome, ketamine‐induced cystitis, characterised by chronic inflammation and urothelial ulceration.
Anis, Baker, Braun, Burnstock, Byth, Chinopoulos, Chopra, Chu, Cross, de la Fuente, Dranka, Gonzalez-Cadavid, Jennifer Southgate, Juhaszova, Machado-Vieira, Nakanishi, Nikolaos T. Georgopoulos, Parkin, Rasola, Saqib Shabir, Shabir, Shahani, Shen, Simon C. Baker, Takadera, Tissot, Vanoevelen, Wang, Winstock, Wong, Wood   +30 more
core   +1 more source

S‐ketamine Alleviates Neuroinflammation and Attenuates Lipopolysaccharide‐Induced Depression Via Targeting SIRT2

Advanced Science, EarlyView.
S‐ketamine binds directly to SIRT2, facilitating its interaction with NF‐κB p65. This interaction reduces the acetylation of NF‐κB p65 and inhibits its activation, thereby exerting anti‐inflammatory and antidepressant effects. Created by BioRender.
Cong Lin, Xiaoxuan Zhou, Mingqi Li, Cong Zhang, Haojiang Zhai, Haohong Li, Hongshuang Wang, Xiaohui Wang   +7 more
wiley   +1 more source

Regulation of PVT‐CeA Circuit in Deoxynivalenol‐Induced Anorexia and Aversive‐Like Emotions

Advanced Science, EarlyView.
The study investigates Deoxynivalenol (DON) effects on feeding and emotions, focusing on the central amygdala (CeA). Acute DON exposure reduces food intake and alters behavior, linked to CeAGABA neuron activity and PVT‐CeA connectivity. Manipulating CeAGABA neurons and using SCN10A antagonist A‐803467 alleviate DON's effects, offering potential ...
Liu‐Nan Yang, Mingmeng Tang, Andreas K. Nüssler, Liegang Liu, Wei Yang   +4 more
wiley   +1 more source

Beneficial effects of arthrocen on neuroinflammation and behavior like depression in stroke in a murine model

Food Science &Nutrition, Volume 11, Issue 1, Page 527-534, January 2023., 2023
Following oral administration of arthrocen supplement in post‐stroke depression model, the study recommended a novel protective effect by arthrocen on neuroinflammation due to stroke. It may play an antidepressant role through anti‐inflammatory as well as improved activity and mobility in mice‐induced stroke.
Ramin Goudarzi, Golnaz Zamanian, Zahra Seyyedian, Partow Mirzaee Saffari, Ahmad Reza Dehpour, Alireza Partoazar   +5 more
wiley   +1 more source

Stereoselective pharmacokinetics of ketamine and norketamine after racemic ketamine or S-ketamine administration during isoflurane anaesthesia in Shetland ponies [PDF]

, 2017
Background The arterial pharmacokinetics of ketamine and norketamine enantiomers after racemic ketamine or S-ketamine i.v. administration were evaluated in seven gelding ponies in a crossover study (2-month interval). Methods Anaesthesia was induced with
Knobloch, M., Kronen, P. W., Landoni, M. F., Larenza, M. P., Levionnois, O. L., Schatzmann, U., Theurillat, R., Thormann, W.   +7 more
core  

OcuPair, a Novel Photo‐crosslinkable PAMAM Dendrimer‐Hyaluronic Acid Hydrogel Bandage/Bioadhesive for Corneal Injuries and Temporary Corneal Repair

Advanced Science, EarlyView.
A schematic diagram showing the OcuPair adhesive hydrogel formulation loaded into the final delivery device and applied over the full‐thickness corneal wound in an in vivo rabbit model of corneal injury followed by in situ crosslinking to form a transparent hydrogel bandage sealing the wound.
Siva P. Kambhampati, Rishi Sharma, Hui Lin, Santiago Appiani, Jeffrey L. Cleland, Samuel C. Yiu, Rangaramanujam M. Kannan   +6 more
wiley   +1 more source

Reactive microglia are the major source of tumor necrosis factor alpha and contribute to astrocyte dysfunction and acute seizures in experimental temporal lobe epilepsy

Glia, Volume 71, Issue 2, Page 168-186, February 2023., 2023
Main Points Microglia become rapidly reactive in temporal lobe epilepsy (TLE). Microglia are major producers of TNFα during status epilepticus, which impairs astrocyte coupling and promotes gliosis. Depletion of microglia attenuates acute seizure activity in TLE.
Lukas Henning, Henrike Antony, Annika Breuer, Julia Müller, Gerald Seifert, Etienne Audinat, Parmveer Singh, Frederic Brosseron, Michael T. Heneka, Christian Steinhäuser, Peter Bedner   +10 more
wiley   +1 more source

The Cognitive Effects of Sub-Anesthetic Ketamine and Lidocaine in individuals with a diagnosis of Chronic Pain [PDF]

, 2020
Background and Aim: Since ketamine was first trialed as an anti-depressant in 2000, it has been growing in popularity due to its fast-onset anti-depressant effects.
Halls, Georgia
core  

A Pilot Study of Ketamine versus Midazolam/Fentanyl Sedation in Children Undergoing GI Endoscopy [PDF]

, 2011
Background. Ketamine sedation has been found superior by physician report to traditional sedation regimens for pediatric endoscopy. Goal. To objectively compare sedation with ketamine versus midazolam/fentanyl for children undergoing gastrointestinal ...
Fox, Victor L., Fredette, Meghan E., Lightdale, Jenifer R., Mahoney, Lisa B., Mitchell, Paul D., Scharff, Lisa, Zgleszewski, Steven E.   +6 more
core   +3 more sources