Results 71 to 80 of about 219,641 (298)
FDA‐approved anti‐inflammatory drug Auranofin inhibits SARS‐CoV‐2 replication by inhibiting viral Main protease activity and Spike processing required for viral entry. It shows strong synergy with nucleoside analogue Remdesivir, due to non‐overlapping mechanisms.
Oyahida Khatun +13 more
wiley +1 more source
Anesthesia of the grey duiker (Sylvicapra grimmia) using a combination of ketamine and xylazine, with reversal by atipamezole [PDF]
Twenty grey duiker (Sylvicapra grimmia) were blow-darted with a combination of ketamine and xylazine, resulting in a level of sedation adequate for capture and minor procedures in 13 of them (mean dosages: ketamine, 13.4 mg/kg; xylazine, 16.8 mg/kg ...
Wilson, K. +3 more
core
Intravitreal AAV2‐mediated AKAP1 restoration enhances mitochondrial fusion and biogenesis, improves bioenergetic capacity, and preserves mitochondrial integrity in glaucomatous RGCs. AKAP1 stabilizes presynaptic structure, maintaining synaptic protein expression, and limiting complement‐associated neuroinflammation.
Tonking Bastola +10 more
wiley +1 more source
Reversible anesthesia of the blue duiker (Cephalophus monticola) with Medetomidine and Ketamine [PDF]
Ten blue duiker (Cephalophus monticola) were blowdarted with a combination of ketamine and medetomidine, resulting in a level of sedation adequate for minor procedures in eight of the duikers (mean dosages: ketamine 2.2 mg/kg and medetomidine 190 µg/kg).
Wilson, K. +3 more
core
Natural Pharmaco‐remedial impacts of Allium sativum on Systemic health. ABSTRACT Arising from the emergence of diverse difficult‐to‐treat health cases, alterative‐therapeutic strategies have become a potential way forward for management/control. In traditional Chinese medicine (TCM), various plant materials have been sourced as alterative‐therapeutic ...
Patience O. Adomi +3 more
wiley +1 more source
Interleukin‐18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis
Interleukin‐18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis. Abstract Background and Aims Nucleotide‐binding oligomerization domain‐like receptor‐family pyrin domain‐containing 3 (NLRP3) inflammasome activation has been shown to result in liver fibrosis.
Jana Knorr +19 more
wiley +1 more source
Effect of Ketamine on Social Avoidance in Socially Defeated Male and Female Syrian Hamsters
Social stress can cause or exacerbate neuropsychiatric illnesses such as depression. Unfortunately, currently available treatments for these disorders are slow to take effect and are often ineffective.
Guzman Bambaren, Alejandro D
core +1 more source
ABSTRACT ADNP‐related Helsmoortel–Van der Aa syndrome (ADNP‐related HVDAS) is a single gene form of autism spectrum disorder (ASD) caused by pathogenic sequence variants in the activity‐dependent neuroprotective protein (ADNP) gene. In addition to ASD, ADNP‐related HVDAS is associated with a wide range of cognitive, behavioral, and physical health ...
Jarrett Fastman +11 more
wiley +1 more source
The effects of adding ketamine to morphine in patient-controlled intravenous analgesia after orthopedic surgeries [PDF]
Aim and Background: A routine method to control post-operative pain is patient-controlled intravenous analgesia (PCIA) using opioids. Regarding complications of opioids, it seems necessary to reduce their dosage and to improve the quality of analgesia ...
ایمانی, فرناد +2 more
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