Results 71 to 80 of about 219,641 (298)

An Oral Antiviral Combination Against Severe COVID‐19 Enabled by the Synergistic Mechanisms of Action of Auranofin and Remdesivir

open access: yesAdvanced Science, EarlyView.
FDA‐approved anti‐inflammatory drug Auranofin inhibits SARS‐CoV‐2 replication by inhibiting viral Main protease activity and Spike processing required for viral entry. It shows strong synergy with nucleoside analogue Remdesivir, due to non‐overlapping mechanisms.
Oyahida Khatun   +13 more
wiley   +1 more source

Anesthesia of the grey duiker (Sylvicapra grimmia) using a combination of ketamine and xylazine, with reversal by atipamezole [PDF]

open access: yes, 1996
Twenty grey duiker (Sylvicapra grimmia) were blow-darted with a combination of ketamine and xylazine, resulting in a level of sedation adequate for capture and minor procedures in 13 of them (mean dosages: ketamine, 13.4 mg/kg; xylazine, 16.8 mg/kg ...
Wilson, K.   +3 more
core  

AKAP1 Protects Retinal Ganglion Cells and Preserves Vision by Improving Mitochondrial and Synaptic Health in Glaucomatous Neurodegeneration

open access: yesAdvanced Science, EarlyView.
Intravitreal AAV2‐mediated AKAP1 restoration enhances mitochondrial fusion and biogenesis, improves bioenergetic capacity, and preserves mitochondrial integrity in glaucomatous RGCs. AKAP1 stabilizes presynaptic structure, maintaining synaptic protein expression, and limiting complement‐associated neuroinflammation.
Tonking Bastola   +10 more
wiley   +1 more source

Reversible anesthesia of the blue duiker (Cephalophus monticola) with Medetomidine and Ketamine [PDF]

open access: yes, 1995
Ten blue duiker (Cephalophus monticola) were blowdarted with a combination of ketamine and medetomidine, resulting in a level of sedation adequate for minor procedures in eight of the duikers (mean dosages: ketamine 2.2 mg/kg and medetomidine 190 µg/kg).
Wilson, K.   +3 more
core  

Allium sativum, a Natural and Pharmaco‐Remedial Panacea for Entero‐Gastritis, Antibiocidal/Dysbiogenesis, and Systemic Health Relevance

open access: yesAgriFood: Journal of Agricultural Products for Food, EarlyView.
Natural Pharmaco‐remedial impacts of Allium sativum on Systemic health. ABSTRACT Arising from the emergence of diverse difficult‐to‐treat health cases, alterative‐therapeutic strategies have become a potential way forward for management/control. In traditional Chinese medicine (TCM), various plant materials have been sourced as alterative‐therapeutic ...
Patience O. Adomi   +3 more
wiley   +1 more source

Interleukin‐18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis

open access: yesHepatology, EarlyView., 2022
Interleukin‐18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis. Abstract Background and Aims Nucleotide‐binding oligomerization domain‐like receptor‐family pyrin domain‐containing 3 (NLRP3) inflammasome activation has been shown to result in liver fibrosis.
Jana Knorr   +19 more
wiley   +1 more source

Ketamine* [PDF]

open access: yesJournal of Pain and Symptom Management, 2011
Rachel, Quibell   +4 more
openaire   +2 more sources

Effect of Ketamine on Social Avoidance in Socially Defeated Male and Female Syrian Hamsters

open access: yes, 2016
Social stress can cause or exacerbate neuropsychiatric illnesses such as depression. Unfortunately, currently available treatments for these disorders are slow to take effect and are often ineffective.
Guzman Bambaren, Alejandro D
core   +1 more source

ADNP‐Related Helsmoortel–Van der Aa Syndrome: A Review of the Literature and Clinical Recommendations for Assessment and Monitoring

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT ADNP‐related Helsmoortel–Van der Aa syndrome (ADNP‐related HVDAS) is a single gene form of autism spectrum disorder (ASD) caused by pathogenic sequence variants in the activity‐dependent neuroprotective protein (ADNP) gene. In addition to ASD, ADNP‐related HVDAS is associated with a wide range of cognitive, behavioral, and physical health ...
Jarrett Fastman   +11 more
wiley   +1 more source

The effects of adding ketamine to morphine in patient-controlled intravenous analgesia after orthopedic surgeries [PDF]

open access: yes
Aim and Background: A routine method to control post-operative pain is patient-controlled intravenous analgesia (PCIA) using opioids. Regarding complications of opioids, it seems necessary to reduce their dosage and to improve the quality of analgesia ...
ایمانی, فرناد   +2 more
core  

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