Results 221 to 230 of about 60,638 (316)

Lactate orchestrates metabolic hemodynamic adaptations through a unique combination of venocontraction, artery relaxation, and positive inotropy

Acta Physiologica, Volume 241, Issue 5, May 2025.
Abstract Aim H+ facilitates metabolic blood flow regulation while negatively impacting cardiac contractility. Cardiovascular consequences of conjugate bases accumulating alongside H+ remain unclear. Here, we evaluate the cardiovascular effects of nine prominent carboxylates—particularly lactate, 3‐hydroxybutyrate, and butyrate—linked to metabolic and ...
Casper Homilius, Jacob M. Seefeldt, Jakob Hansen, Roni Nielsen, Frank V. de Paoli, Ebbe Boedtkjer   +5 more
wiley   +1 more source

Protocol for a feasibility and acceptability study for UK general population paediatric type 1 diabetes screening—the EarLy Surveillance for Autoimmune diabetes (ELSA) study

Diabetic Medicine, Volume 42, Issue 5, May 2025.
Abstract Aim The EarLy Surveillance for Autoimmune (ELSA) study aims to explore the feasibility and acceptability of UK paediatric general population screening for type 1 diabetes. Methods We aim to screen 20,000 children aged 3–13 years for islet‐specific autoantibodies through dried blood spot sample collection at home, hospital or community settings.
Lauren M. Quinn, Renuka P. Dias, Sheila M. Greenfield, Alex G. Richter, Joanna Garstang, David Shukla, Animesh Acharjee, Georgios Gkoutos, Richard Oram, Sian Faustini, Olga Boiko, Ian Litchfield, Felicity Boardman, Fatima Zakia, Christine Burt, Clair Connop, Amanda Lepley, Christine Gardner, Colin Dayan, Tim Barrett, Parth Narendran   +20 more
wiley   +1 more source

Variability in HbA1c and the risk of major clinical outcomes in type 2 diabetes with chronic kidney disease: Post hoc analysis from the CREDENCE trial

Diabetes, Obesity and Metabolism, Volume 27, Issue 6, Page 3531-3535, June 2025.
Ying Zhu, Min Jun, Robert A. Fletcher, Clare Arnott, Brendon L. Neuen, Sradha S. Kotwal   +5 more
wiley   +1 more source

A trauma‐informed approach to type 1 diabetes mellitus in adults

Diabetic Medicine, Volume 42, Issue 5, May 2025.
Suggested mechanisms for an association between early life adversity and worse glycaemic control.
Hadassah Buechner, Shreena Unadkat, Joanne Skeldon, Gregory C. Jones   +3 more
wiley   +1 more source

Tislelizumab-induced type 1 diabetic ketoacidosis in a patient with small cell lung cancer: a case report. [PDF]

Front Oncol
Zhu J, Wang WJ.
europepmc   +1 more source

Extended use of real‐time continuous glucose monitoring in adults with insulin‐requiring type 2 diabetes: Results from the first 26 weeks of the 2GO‐CGM trial

Diabetic Medicine, Volume 42, Issue 5, May 2025.
Abstract Aims The first 26 weeks of the 2GO‐CGM trial assessed the efficacy and safety of real‐time continuous glucose monitoring (rtCGM) use within a supported specialist model of care in a cohort of community‐based adults with insulin‐requiring type 2 diabetes in New Zealand.
Claire S. Lever, Jonathan A. Williman, Alisa Boucsein, Antony Watson, Rachael S. Sampson, Oscar T. Sergel‐Stringer, Celeste Keesing, Benjamin J. Wheeler, Martin I. de Bock, Ryan G. Paul   +9 more
wiley   +1 more source

Hospital management of diabetic ketoacidosis in the U.K. [PDF]

, 2000
Laura S. Buchanan, Ken Paterson
openalex   +1 more source

Real‐world experiences of adult individuals or caregivers of children who received teplizumab treatment in stage 2 type 1 diabetes

Diabetes, Obesity and Metabolism, Volume 27, Issue 5, Page 2495-2506, May 2025.
Abstract Aims This study surveyed individuals and caregivers of children who received teplizumab at stage 2 type 1 diabetes (T1D) to garner real‐world experiences and their health outlook for the future following treatment with the first approved disease‐modifying immune therapy for delaying the onset of Stage 3 T1D.
Holly K. O'Donnell, Kimber M. Simmons, Stephen E. Gitelman, Terry Dex, Robert Hill, Mattias Wieloch, Julia Zaccai, Jennifer D'Souza, France Ginchereau Sowell, James Turnbull, Korey K. Hood   +10 more
wiley   +1 more source

SGLT-2 inhibitor induced Euglycemic diabetes ketoacidosis in post laparoscopic distal pancreatectomy: A case report. [PDF]

Int J Surg Case Rep
Chen CC, Feng TY, Wang SC, Chen TH, Chou SJ, Jan HC.   +5 more
europepmc   +1 more source

Capivasertib-Induced Diabetic Ketoacidosis in a Non-diabetic Patient With Metastatic Prostate Cancer With Bone Involvement: A Case Report of a Rare but Serious Metabolic Complication. [PDF]

Cureus
Habeb B, Valdes O, Khair S, Sidhu G, Fowler M.   +4 more
europepmc   +1 more source