Results 181 to 190 of about 42,303 (288)

Aminoacyl‐tRNA Synthetases: Variant Classification, Functional Assays, and Emerging Therapeutic Strategies

open access: yesJournal of Inherited Metabolic Disease, Volume 49, Issue 3, May 2026.
ABSTRACT Aminoacyl‐tRNA synthetases (aaRS) are essential enzymes that charge tRNAs with their corresponding amino acids, playing a critical role in protein synthesis. All 37 nuclear‐encoded ARS genes, comprising both cytosolic (ARS1) and mitochondrial (ARS2) isoforms, have now been linked to human disease.
M. I. Mendes   +17 more
wiley   +1 more source

Liver Stiffness Characterization of OGTLKO Mouse Model of Progressive Liver Fibrosis

open access: yesJournal of Ultrasound in Medicine, Volume 45, Issue 5, Page 1069-1082, May 2026.
Objectives O‐GlcNAcylation plays a key regulatory role in hepatic physiology, and its disruption leads to fibrosis in liver‐specific OGT knockout mice (OGTLKO), making this model valuable for studying advanced metabolic dysfunction‐associated steatohepatitis (MASH).
Gilles Renault   +9 more
wiley   +1 more source

Improvement in patient-reported sleep in type 2 diabetes and prediabetes participants receiving a continuous care intervention with nutritional ketosis [PDF]

open access: yes, 2019
Athinarayanan, Shaminie   +9 more
core   +1 more source

Intratumoral Microorganisms in Tumors: Current Understanding and Emerging Therapeutic Strategies

open access: yesMedComm, Volume 7, Issue 5, May 2026.
Tumors are no longer viewed as sterile but dynamic ecosystems harboring low‐biomass intratumoral microbiota. These microbes, derived from gut, oral cavity, or circulation, shape tumorigenesis and therapy response via core mechanisms: immunomodulation (regulating T cells, macrophages), metabolic reprogramming (SCFAs, indoles, bile acids), chronic ...
Haoling Zhang   +8 more
wiley   +1 more source

Correction: Ketogenic diet improves disease activity and cardiovascular risk in psoriatic arthritis: A proof of concept study. [PDF]

open access: yesPLoS One
Ramonda R   +11 more
europepmc   +1 more source

Chronic Pain: Epidemiology, Pathophysiology, and Clinical Management

open access: yesMedComm, Volume 7, Issue 5, May 2026.
The multidimensional nature of chronic pain is illustrated through four interconnected domains. (Left) Epidemiology and Global Burden: Chronic pain affects approximately one in five individuals globally, contributing to a rising trend in disability‐adjusted life years (YLDs) and a significant socioeconomic impact.
Zhihao Shang   +12 more
wiley   +1 more source

Home - About - Disclaimer - Privacy