Results 71 to 80 of about 22,612 (263)

Ketogenic diet in civilization diseases

open access: yesJournal of Education, Health and Sport, 2018
The low-carbohydrate ketogenic diet (LCKD) is a high fat and low carbohydrate and low protein diet. It was found to be promising in controlling diabetes mellitus. (DM)., epilepsy, obesity, cardiovascular diseases.
Monika Kusz   +4 more
doaj  

Functional/dissociative seizures as a manifestation of forced normalization in eyelid myoclonia with absence epilepsy

open access: yes
Epileptic Disorders, EarlyView.
Fernando Vasquez‐Lopez   +16 more
wiley   +1 more source

New onset refractory status epilepticus (NORSE) versus refractory status epilepticus not meeting NORSE criteria: A comparative clinical and electroencephalography‐based study

open access: yesEpilepsia, EarlyView.
Abstract Objective New onset refractory status epilepticus (NORSE) is a rare, severe presentation of refractory status epilepticus (RSE), with approximately half of cases cryptogenic NORSE (c‐NORSE). We compared electroencephalographic (EEG) findings alongside clinical features between NORSE and RSE not meeting NORSE criteria to better understand ...
Seren Hawksworth   +6 more
wiley   +1 more source

Epilepsy‐associated SCN2A‐L1342P mutation drives network hyperexcitability and widespread transcriptomic changes in human cortical organoids

open access: yesEpilepsia, EarlyView.
Abstract Objective SCN2A pathogenic mutations, such as the recurrent heterozygous Nav1.2‐L1342P, are monogenic causes of epilepsy. In this human‐induced pluripotent stem cell–derived model system, we aim to investigate the molecular and cellular mechanisms underlying SCN2A‐L1342P‐associated pathology. Methods Using a human male induced pluripotent stem
Maria I. Olivero‐Acosta   +26 more
wiley   +1 more source

Therapeutic ketogenic diet as treatment for anorexia nervosa

open access: yesFrontiers in Nutrition
Anorexia nervosa (AN) is a severe psychiatric disorder. However, we lack neurobiological models and interventions to explain and treat the core characteristics of food restriction, feeling fat, and body size overestimation.
Guido K. W. Frank, Barbara Scolnick
doaj   +1 more source

Inherited metabolic epilepsies–established diseases, new approaches

open access: yesEpilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

D,L‐3‐hydroxybutyrate in the treatment of glucose transporter 1 deficiency syndrome (Glut1DS)

open access: yesJIMD Reports
Background Deficiency of the Glut1 transporter due to mono‐allelic variants in SLC2A1 causes hypoglycorrhachia, resulting in a neurological spectrum from neonatal epilepsy to adult‐onset paroxysmal movement disorders (PMD).
Aya Amer   +7 more
doaj   +1 more source

TOWARD, a metabolic health intervention, demonstrates robust 1-year weight loss and cost-savings through deprescription

open access: yesFrontiers in Nutrition
BackgroundCost, scalability, and durability represent major challenges to the implementation of intensive lifestyle treatments for obesity and diabetes.
Laura Buchanan   +8 more
doaj   +1 more source

Intestinal microbiome alterations in pediatric epilepsy: Implications for seizures and therapeutic approaches

open access: yesEpilepsia Open, EarlyView.
Abstract The intestinal microbiome plays a pivotal role in maintaining host health through its involvement in gastrointestinal, immune, and central nervous system (CNS) functions. Recent evidence underscores the bidirectional communication between the microbiota, the gut, and the brain and the impact of this axis on neurological diseases, including ...
Teresa Ravizza   +4 more
wiley   +1 more source

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